Strong-stability film-forming nipple protecting liquid for cows and preparation process thereof

A technology with strong stability and high preparation technology, which is applied in the fields of emulsion transportation, active ingredients of artificially synthesized polymer materials, diseases, etc., and can solve problems such as slow film formation speed and unstable film formation effect of povidone-iodine solution

Inactive Publication Date: 2013-03-13
HENAN KANGXING PHARMA
View PDF2 Cites 15 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

2. Solve the problems of instability and poor film-forming effect of povidone-iod

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Example Embodiment

Implementation case 1

The specific embodiment of the present invention for preparing 1000mL milk cow stable and film-forming povidone-iodine protective emulsion, the weight ratio is as follows:

Sodium lauryl sulfate 50g

Povidone iodine 50g

Dimethyl sulfoxide 20g

Potassium iodate 20g

Glycerin 20g

Sodium lauryl sulfate 60g

Phosphate buffer 80g

Purified water 700g

The specific preparation process is as follows:

(1) Melt povidone iodine and an appropriate amount of purified water completely, add sodium lauryl sulfate, stir evenly, and filter to obtain solution A;

(2) Mix the polyvinyl alcohol with an appropriate amount of purified water, fully stir to make it fully swell into a transparent liquid, and filter to obtain the B solution;

(3) Prepare phosphate buffer solution and adjust its pH value to 5-6 to obtain C solution;

(4) Prepare potassium iodate solution, add potassium iodate solution to the mixture of appropriate amount of glycerin and dimeth...

Example Embodiment

Implementation case 2

The specific embodiment of the present invention for preparing 1000mL milk cow stable and film-forming povidone-iodine protective emulsion, the weight ratio is as follows:

Povidone iodine 100g

Povidone iodine 100g

Potassium iodate 25g

Glycerin 40g

Glycerin 40g

Sodium lauryl sulfate 50g

Phosphate buffer 100g

Purified water 545g

The specific preparation process is as follows:

(1) Melt povidone iodine and an appropriate amount of purified water completely, add sodium lauryl sulfate, stir evenly, and filter to obtain solution A;

(2) Mix the polyvinyl alcohol with an appropriate amount of purified water, fully stir to make it fully swell into a transparent liquid, and filter to obtain the B solution;

(3) Prepare phosphate buffer solution and adjust its pH value to 5-6 to obtain C solution;

(4) Prepare potassium iodate solution, add potassium iodate solution to the mixture of appropriate amount of glycerin and dimethyl sulfox...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The invention belongs to the technical field of drug preparation and in particular relates to strong-stability film-forming nipple protecting liquid for cows and a preparation process thereof. The liquid is characterized by comprising the following components by weight percent: 1-10% of povidone-iodine, 1-15% of film-forming agent, 0.5-5% of stabilizing agent, 0.1-4% of protective agent, 1-5% of antifreezing agent, 5-10% of surfactant, 5-20% of phosphate buffer and purified water. The preparation process comprises raw material treating, mixing, activating, filtering, PH value regulating, volume metering, subpackaging and sealing. After the cows are milked and before the nipple catheter is not closed, pathogenic bacteria intrude into the nipples very easily; therefore the film-forming nipple protecting liquid should be used instantly after milking the cows to quickly form a layer of film on the nipples to isolate the outside pathogenic microorganisms, thus reducing the incidence rate of mastitis, simultaneously protecting the nipples from frostbites and suncrack and ensuring stability of the povidone-iodine solution.

Description

technical field [0001] The invention belongs to the field of medicine preparation, in particular to a highly stable film-forming protective emulsion for dairy cows and a preparation process thereof. Background technique The treatment of cow mastitis is more and more difficult to cure, and people pay more and more attention to the prevention of mastitis. Add some effective traditional Chinese medicine preparations for prevention during the feeding process of dairy cows. Recently, people have begun to disinfect the teats of dairy cows to prevent mastitis, and teat dipping liquid products have also begun to appear. Povidone-iodine film-forming nipple dips have appeared on the market. Povidone-iodine is recognized as a new type of high-efficiency, broad-spectrum, less irritating, non-toxic and side effects, no residue, and no drug resistance fungicide. It has a strong killing effect on Staphylococcus aureus, Pseudomonas aeruginosa, hepatitis B virus, HIV, Trichomonas vagina...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
IPC IPC(8): A61K9/107A61K31/79A61P31/04A61P15/14
Inventor 常丽君张国祖李晓翠夏换王巧红
Owner HENAN KANGXING PHARMA
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap