77 results about "Povidone-Iodine Solution" patented technology

The invention discloses a povidone-iodine disinfectant and a preparation method thereof. The povidone-iodine disinfectant comprises povidone-iodine (PVP-I), potassium iodate and potassium iodide. Critic acid and sodium hydroxide are used for adjusting the pH of a solution. The povidone-iodine solution contains potassium iodate and potassium iodide, and under an acid environment, a reaction of IO3<->+5I<->+H<+>=3I2+3H2O exists in the solution. Effective iodine concentration in the solution is increased, active iodine is promoted to be released slowly, and disinfecting time of the povidone-iodine disinfectant is prolonged.

The invention discloses an individual labeling method for selective breeding of tilapia. Firstly, an appropriate plastic pin, a tagging gun, a closed loop plastic tag and so on, are selected; secondly, Tricaine methane sulphonate with a concentration of 0.33g / L is used to anesthetize the tilapia; and then a fish body is labeled. The tilapia is kept a posture of swimming during the labeling and faces toward the left side; an insertion point is positioned at the front end on the back of the fish body; the closed loop plastic tag is sleeved on a gun needle; the plastic pin directly passes through the fish body to fix a label, and the length of the plastic pin exposed outside the fish body is between 2 and 4cm; and finally the labeled tilapia is placed into a 10 percent povidone iodine solution for soaking disinfection. The method has the advantages of simple operation, low cost, and high automation, has less damage degree to the fish body, ensures that the retention rate of the label is more than 90 percent and the effective recognition rate is more than 90 percent, can not affect the normal activity of the tilapia, and can meet the need of large-scale labeling of selective breeding of the tilapia.

The invention belongs to the technical field of medicine preparation, and particularly relates to a 5% povidone-iodine solution for dairy cattle with strong stability and a preparation process thereof. The 5% povidone-iodine solution for dairy cattle with strong stability is characterized by comprising the components by weight percentage as follows: 5% of povidone-iodine, 1-5% of cosolvent, 1-5% of stabilizer, 1-10% of protective agent, 1-5% of antifreezing agent, 5-10% of surfactant, 5-20% of phosphate buffer and purified water. The preparation process comprises the steps of: processing materials; mixing; activating; filtering; adjusting pH values; setting volume; packaging; and sealing. The 5% povidone-iodine solution for dairy cattle with strong stability is used before or after milking the cattle to prevent mastitis of the dairy cattle. Meanwhile, nipples are prevented from being frozen and cracked, and the stability of the povidone-iodine solution at high and low temperatures is guaranteed.

The invention discloses a fry culture cultivating method for schizothorax prenanti. After a fish pond is disinfected, fish fry disinfected with a povidone-iodine solution are put in the pond, micro-flow water is adopted for cultivation, cooked egg yolk is thrown and fed to the fry for several days, plankton bait is thrown and fed to the fry after 5-7 days, cut water earthworms and broken juvenile schizothorax prenanti materials are thrown and fed to the fry after 20 days, and juvenile schizothorax prenanti feed is thrown and fed to the fry till the fry reach the specification of larva fish. The schizothorax prenanti fish fry cultivated through the method are low in cost, high in survival rate and quick in growth, the cooked egg yolk, the rotifer and cladocera plankton bait, and the water earthworms and the juvenile schizothorax prenanti feed are thrown and fed to the fry in a staged mode, and therefore the high growth rate can be kept at each stage.

The invention discloses a formula and a preparation process of povidone iodine gel for veterinary use, and particularly relates to povidone iodine gel for veterinary use and a preparation process. The prescription of the medicament consists of povidone iodine, a moisturizing lubricant, a gel matrix, a stabilizer, buffer solution and sterilized water. According to the preparation process, the PH value and the proportion are adjusted to process the povidone iodine gel. The povidone iodine in the gel has the advantages of high bactericidal power, wide antibacterial spectrum, small stimulus, no allergenicity, low toxicity, no drug resistance, no influence on quality of lactation milk, no milk withdrawal period and insensitivity of a sow to the smell of the gel; after the povidone iodine is prepared into the gel, effective iodine of the povidone iodine is more stable to fulfill the aims of slow release and high efficiency; the moisturizing lubricant is added into the gel, so that the povidone iodine is close to the wall of uterus in the uterus and is easier to absorb; and through the stabilizer and the buffer solution in the gel, the effective iodine is stable, and the influence of external environment is avoided.

The invention discloses a disinfecting and antibacterial washing powder comprising the components of, by weight, 10-20% of sodium dodecyl sulfate, 1-5% of fatty alcohol polyoxyethylene ether, 10-20% of sodium tripolyphosphate, 20-40% of sodium sulphate, 1-5% of sodium metasilicate, 0.1-2% of acetylsalicylic acid, 0.5-2% of salicylic acid, 0.5-2% of a povidone iodine solution, 0.5-2% of glycerol, and 0.1-0.5% of a brightening agent. The washing powder provided by the invention has the advantages of reasonable formula and good decontamination effect. The salicylic acid and povidone iodine solution are used in combination, such that good disinfecting and bacterium-regeneration-inhibiting effects are provided, and cross-infection is prevented when clothes are washed together. The washing powder is suitable to be used in public places.

The invention discloses a povidone iodine, which comprises the following components: 10.0%-50.0% of polyvinylpyrrolidone k30, 2.34%-11.44% of iodine, 1.17-5.72% of potassium iodide, 5.0-45.0% of a solvent n-propanol, 0.01%-10.0% of a stability auxiliary agent and the balance of water. The invention also discloses a preparation method of povidone iodine. The preparation method of povidone iodine provided by the invention employs a solution method for complex of polyvinylpyrrolidone, iodine and additives under certain conditions, so as to prepare a povidone iodine solution; povidone iodine obtained by complexation of povidone and iodine has good stability, meets the requirements of the medical disinfection industry on povidone iodine, and solves the problem of poor stability of povidone iodine. At the same time, povidone iodine prepared by water solution method is more convenient for usage.

Disclosed are compositions and methods comprising povidone-iodine and a cooling-effective amount of a chemical agent. The compositions are useful to relieve mild ocular irritation, enhance ocular comfort, and to provide a refreshing effect and improved sensation, when the povidone-iodine solution is applied to the eye.

The coupling agent for B-mode ultrasound diagnostic instrument consists of povidone-iodine 0.5-5 %, glycerin 1-7 %, sodium carboxy methyl cellulose 3-6 %, ethanol 10-15 % and pure water 67-85.5 %. During its preparation, povidone-iodine is first dissolved in water, sodium carboxyl methyl cellulose and ethanol are mixed homogeneously through stirring, the povidone-iodine solution is then mixed with mixed sodium carboxy methyl cellulose and ethanol solution through stirring, and the mixed solution is 80-120 mesh filtered to obtain the coupling agent. The coupling agent is used in supersonic test in hospital and can kill bacteria and virus and prevent crossed infection.

The invention relates to a povidone-iodine solution and a preparation method thereof. Each 100g of the povidone-iodine solution is mainly prepared from, by weight, 0.02-0.5g of potassium iodate, 0.1-3.5g of potassium iodide, 0.5-5g of PVP, 1-5g of polyethylene glycol, 2-10g of polyurethane, 0.1-5g of sodium alginate, 0.2-0.5g of organic acid, 0.5-3.5g of surfactant, 1-5g of plasticizer and the balance of water and pH regulator. The povidone-iodine solution is safe, reliable, high in stability and good in film forming effect, a film formed by the solution is not high in toughness and less proneto shedding, efficacy is lasting, antibacterial effect is ensured, a lot of labor and medication cost can be saved, and the solution is suitable for extensive dairy cow farms.

The invention relates to a compound polyninylpyrrolidone sterilizing agent and a preparation method thereof. The sterilizing agent comprises the following components (by wt%): 2.0-10.0% of povidone-iodine PVP-I, 0.05-0.5% of vitamin A, 0.5-1.0% of potassium iodate KIO3, 0.5-1.0% of potassium iodide KI, 0.2-2.0% of chelating agent, 1.0-10.0% of organic solvent, a proper amount of pH modifier, and the balance of water. The preparation method comprises the steps of a. dissolving the povidone-iodine PVP-I and potassium iodate KIO3 into a proper amount of purified water; b. adding the chelating agent and mixing uniformly; c. adding the potassium iodide KI and mixing uniformly; d. adding the vitamin A into the organic solvent and dissolving; e. adding a vitamin A solution d into a povidone-iodine solution c, and mixing uniformly; and f. adjusting the pH to be 7.0-8.0 with the pH modifier, so as to obtain the compound polyninylpyrrolidone sterilizing agent. The compound polyninylpyrrolidone sterilizing agent has stable property and strong sterilizing effect, and can promote wound healing.

The invention discloses a silkworm disinfectant. The silkworm disinfectant is obtained by mixing 30-60V% of a traditional Chinese medicinal sterilization solution, 1-8V% of a chlorine dioxide disinfectant, 1-5V% of a povidone iodine disinfectant and 5-15V% of nimbin missible oil, and the pH value of the silkworm disinfectant is 6.0-7.0; and the chlorine dioxide disinfectant is an activator activated chlorine dioxide solution with the effective content of 10.8-17.5mg / L, and the povidone iodine disinfectant is a povidone iodine solution with the effective iodine content of 2-4g / L. The traditional Chinese medicinal sterilization solution with sterilization and pest killing effects is adopted as a min agent and is compounded with the chlorine dioxide disinfectant, the povidone iodine disinfectant and nimbin missible oil, so the silkworm disinfectant has the advantages of wide sterilization spectrum, good sterilization effect, short period, no chemical residual, no pollution to environment, facilitation of control of pest diseases in the silkworm breeding period, and suitableness for disease control of other vegetables, fruits and crops.

The invention belongs to the technical field of drug preparation and in particular relates to strong-stability 10% povidone-iodine solution for cows and a preparation process thereof. The solution is characterized by comprising the following components by weight percent: 10% of povidone-iodine, 1-5% of stabilizing agent, 1-10% of protective agent, 1-5% of antifreezing agent, 5-10% of surfactant, 5-20% of phosphate buffer and purified water. The preparation process comprises raw material treating, mixing, activating, filtering, PH value regulating, volume metering, subpackaging and sealing. Used before or after milking the cows, the solution prevents mastitis of the cows, simultaneously protects the nipples from frostbites and suncrack and ensures the stability during high and low temperatures.

The invention relates to a sanitizer, in particular to a foam type external skin sanitizer and a preparation method thereof. The foam type external skin sanitizer comprises the following components in percentage by weight: 5.0 to 10.0 percent of povidone iodine, 1.0 to 2.0 percent of PVP, 0.05 to 0.08 percent of chlorhexidine acetate, 0.5 to 2.0 percent of benzyl alcohol and the balance of purified water. The preparation method for the sanitizer comprises the following steps of: properly swelling and dissolving the PVP and the povidone iodine by adding the purified water according to the content and components, dissolving the chlorhexidine acetate and the benzyl alcohol by using the purified water with the temperature of 50 DEG C in another container, and uniformly stirring; adding the solution of the PVP and the povidone iodine into the mixture of the chlorhexidine acetate and the benzyl alcohol, and uniformly stirring to obtain the sanitizer. The sanitizer can be applied to the sanitizing treatment of various wounds on the surfaces of human bodies.

The invention discloses a povidone-iodine solution with enhanced stability and a preparation method thereof. The povidone-iodine solution consists of povidone iodine, sodium dihydrogen phosphate, disodium hydrogen phosphate dodecahydrate, potassium iodate, lauryl sodium sulfate and purified water, and the concentrations of the raw materials are as follows: 5-20 g / L of povidone iodine, 1-10 g / L ofsodium dihydrogen phosphate, 0.5-2 g / L of disodium hydrogen phosphate dodecahydrate, 0.2-1.0 g / L of potassium iodate, and 1-10 g / L of lauryl sodium sulfate, and the pH of a sodium hydroxide solution is adjusted to 5.20-5.30. The sodium dihydrogen phosphate and the disodium hydrogen phosphate dodecahydrate are used as a pH value adjusting buffer pair, so that the acid-base balance of the solution can be maintained, and a buffer effect can be achieved. The potassium iodate and the lauryl sodium sulfate are used as pH stabilizers, the sodium hydroxide is used as a pH regulator, and the pH value of the povidone-iodine solution can be controlled within a specified range, so that the stability of the effective iodine content is ensured, and the bactericidal efficacy of the povidone-iodine solution is maintained.

The present invention discloses one kind of compound iodized chitosan filming agent for preventing and treating mammitis of cow and ewe and its preparation process, and aims at providing filming agent with reasonable recipe, easy preparation, low cost and high curative effect. The compound iodized chitosan filming agent has the components, including chitosan 1-5 wt%, dandelion 3-20 wt%, Viola yedoensis 1.5-10 wt%, forsythia 3-20 wt%, polvidone iodine 0.02-1 wt%, propylene glycol 0.5-4 wt%, Tween-20 0.1-4 wt%, glacial acetic acid 0.5-2 wt%, and water 50-90 wt%. Its preparation process includes the following steps: 1. dissolving chitosan in water, and adding glacial acetic acid, propylene glycol and Tween-20; 2. extracting volatile oil with the Chinese medicinal materials, decocting, filtering, etc to obtain Chinese medicine extractum; 3. dissolving polvidone iodine in water; and 4. adding the extractum, the polvidone iodine solution into the chitosan solution, and adding water.

The invention discloses a coregonus peled fry breeding method. The water source employs spring; the water temperature is 10 to 16 DEG C; the dissolved oxygen is over 7mg / L; the pH value is 6.5 to 7.5; and the water flow speed can be adjusted in a range from 0.4 to 1.5 m / s. An area occupied by a fry breeding pool is 20 to 23 m<2> and the water depth is 50 to 80 cm; and an area occupied by a plankton breeding pool is 155 to 165 m<2> and the water depth is 80 to 120 cm. The method comprises: the fry breeding pool and the plankton breeding pool are sterilized by potassium permanganate and then larval stage feed is cultivated in the plankton breeding pool; coregonus peled spray sterilized by a povidone-iodine solution is put into the fry breeding pool and breeding is carried out by slow flowing water; larval stage feed with the 20% of total weight is fed each day and feeding is carried out at least seven days; and then breeding is carried out continuously at a food conversion breeding state. With the method, the coregonus peled spray is bred; and the cost is low, the survival rate is high, and the growth speed is fast.

The invention discloses a deciquam and iodine compound disinfectant, which comprises the components by weight percent to prepare an intermediate product: 1.00-4.50 percent of iodine; 0.01-0.10 percent of potassium iodide, 30-50 percent of deciquam; 15-30 percent of surfactant; the balance of solubilizer; the intermediate product is obtained, and then water is added into the intermediate product for dilution so as to obtain the final product. The disinfectant has disinfection efficiency upon the bacteria, and the escherichia coli 8099 is taken as an example and the deciquam solution and the povidone iodine solution are taken as the comparison to conduct a sterilizing experiment to achieve the same disinfection efficiency (sterilizing rate is equal to or greater than 99.9 percent), the minimum concentration of deciquam and iodine of the invention is 25mg / L and 1,25mg / L respectively; the minimum concentration of deciquam in the deciquam solution is 63mg / L, and the minimum concentration of iodine in povidone iodine is 2.5mg / L, and the result indicates that the minimum sterilizing concentration of deciquam and iodine is remarkably reduced. The porcine parvovirus virus is taken as an example to indicate the disinfection efficiency upon the virus of the disinfectant, and the result indicates that the inactivation ratio of the disinfectant reaches over 99.9 percent, while the deciquam solution cannot kill the porcine parvovirus virus. The experiment indicates that iodine and deciquam of the compound disinfectant are subjected to complexing to form an entirety under the action of the surface active agent and the like, and the compound disinfectant has a strong synergistic effect.

The invention relates to an anti-leaking povidone iodine solution and a preparation method thereof. Each 1000g of anti-leaking povidone iodine solution is mainly prepared from the following raw materials in parts by weight: 0.3-5g of potassium iodate, 0.3-35g of potassium iodide, 10-25g of PVP (Polyvinyl Pyrrolidone), 2-10g of organic acid, 1-10g of surfactant, 0.5-10g of suspending agent, 18-30gof emollient and the balance of water and pH (Potential of Hydrogen) modifier, wherein the mass ratio of the PVP and the suspending agent is (3.5-5):1. The product has the advantages of good stability, less possibility of leaking, slow releasing, long-lasting pesticide effect, high antibacterial effect and skin protection, a great quantity of manpower and pharmacy cost can be saved, and the anti-leaking povidone iodine solution is suitable for extensive dairy farms.

The invention discloses a povidone iodine cotton swab cylinder based on liquid level detection. The povidone iodine cotton swab cylinder comprises a cylinder body and a cylinder cover connected to thecylinder body and also comprises a compressed air bag arranged in the cylinder body and used for storing a povidone iodine solution, a blocking piece, a liquid level detection meter, a controller, apower supply battery and a displayer, wherein the bottom of the compressed air bag is fixedly arranged at the bottom of the cylinder body, the surface of the compressed air bag is fixed to the bottomsurface of the blocking piece through a spring, a liquid outlet of the compressed air bag penetrates through the blocking piece and then extends out, the liquid level detection meter is fixedly arranged in the compressed air bag and used for detecting the liquid level of the povidone iodine solution in the compressed air bag to obtain a detection signal and is connected with the controller, the controller is connected with the power supply battery and the displayer, the controller is used for processing the detection signal to obtain a liquid level value and controlling the displayer to display the liquid level value. The povidone iodine cotton swab cylinder achieve automatic liquid supply and liquid level detection, achieves an efficient and quick cotton swab containing function and is simple in operation, small in size and convenient to operate.

The invention relates to a soft-shelled turtle growth promotion culture method, comprising the following steps: selecting a pond with area of 2 mu, water depth being 1 m, controlling water temperature of the pond to be 28 DEG C, controlling pH value to be 7.5, ensuring the pond to have relatively high lighting degree; using 10 days before putting soft-shelled turtles in the pond to disinfect the pond; soaking soft-shelled turtle fries in a povidone-iodine solution for 2-5 min; putting the soft-shelled turtle fries in the pond in average density of 15 in each square meter; preparing a fodder, measured according to parts of component by weight, including 50 parts of shrimp meat, 40 parts of peanut kernel cakes, 5 parts of yeast, 2 parts of seaweed meal, and 3 parts of decavitamin; feeding twice every day, feeding amount being 6% of total weight of fed soft-shelled turtles, disinfecting once every 20 days at ordinary times. Compared with the prior art, synergistic effect of microelement in the seaweed meal and the decavitamin is used, to supplement more protein, and improve meat quality and improve organ quality and organ immunity, prevent occurrence of diseases, improve growth speed of soft-shelled turtles, and reduce feeding cost.

The invention discloses an iodine antibacterial textile product. The iodine antibacterial textile product mainly comprises povidone iodine, polyamide fiber, an interface agent, an inner lubricating agent and an outer lubricating agent. The invention also discloses a processing technology and the application of the iodine antibacterial textile product. The processing technology and application comprise the following steps: (1) grinding polyamide fiber granules into powder and putting into a heating and stirring tank; (2) preparing a povidone iodine solution and pouring the prepared solution into the stirring tank; and adding adjuvants into the heating and stirring tank and stirring. According to the iodine antibacterial textile product as well as the processing technology and the application thereof, which are provided by the invention, the production of new antibacterial fiber can be completed well, the antibacterial fiber prepared by the existing metal silver and oxide thereof is replaced well, a human body is protected well while the antibacterial effect of the product is not reduced, the production and use costs of the product can be reduced well, and popularization and sale ofthe products are further promoted.

The invention discloses an in-situ preparation and application method for an povidone iodine-based antimicrobial micro-nano fiber dressing. The method comprises the steps that a high-molecular polymeris totally dissolved with absolute ethyl alcohol, and a high-molecular solution is prepared; an povidone iodine-based material is dissolved into the high-molecular solution and stirred until to be totally uniform, and a spinning precursor solution is obtained; the prepared spinning precursor solution is added into a syringe, the syringe is put into a portable electrostatic spinning device, the device is started, a spinning parameter is adjusted until fibers are uniformly sprayed out, the spacing distance between a sprayer mouth and a receiving wound is controlled, and then it can be achievedthat the antimicrobial nanometer fiber dressing can be prepared on the wound in situ. The preparation method can make the antimicrobial fiber film dressing perfectly fit the wound through the action of electrostatic force, and the nanometer fiber film is high in air permeability. Besides, povidone iodine is used as an antimicrobial component, the cost is low, the antimicrobial effect is good, andthe irritation of a common povidone iodine solution to the wound can be reduced. The in-situ preparation and application method is wide is application prospect.

The invention belongs to the technical field of disinfectants, and particularly relates to a povidone-iodine solution and a preparation method thereof. The povidone-iodine solution provided by the invention is prepared from povidone-iodine, monopotassium phosphate, dipotassium phosphate, potassium iodate, glycerinum, aloe zinc-polysaccharide and sodium citrate. The povidone-iodine solution prepared by the preparation method has the advantages of high stability, remarkable sterilizing effect and durable effect. Meanwhile, the povidone-iodine solution provided by the invention also has the effects of stopping bleeding, clearing free radicals in wounds and preventing wound pollution, and can effectively facilitate wound healing. When the povidone-iodine solution is applied to bathing of piglets, the disease infection prevention ability of piglets can be enhanced, and adverse reactions due to stress reaction can be improved, so that the health level of the piglets is raised. The povidone-iodine solution is an ideal disinfection liquid suitable for piglets.

The invention relates to a Chinese softshell turtle breeding method. The method comprises a parent breeding process. The parent breeding process comprises the following steps: before the parents are put into a breeding pond, adding quick lime into the breeding pond to carry out water pond cleaning, pumping the water in the breeding pond and sun drying the pond; refilling the pond with water, sterilizing the parents with povidone iodine solution and then putting the parents into the breeding pond; performing bait feeding and water quality control by stages, wherein the bait comprises a turtle feed, fresh fishes and / or shrimps and vegetable; the water quality control enables the transparency of water in the breeding pond to be 25-40 cm by water change operation. The method is more scientific and is easy to produce and operate, in general the parent breeding process greatly improves the egg yield of parents and the hatching rate of turtle eggs, and moreover the vitality and the survival rate of the hatched juvenile soft-shelled turtles are greatly improved.

The invention discloses a povidone-iodine pharmaceutical composition for treating skin and mucosa infection as well as a preparation method and application thereof. The pharmaceutical composition is prepared from a povidone-iodine solution and various vitamin zinc tablets, wherein the various vitamin zinc tablets contain zinc gluconate, thiamine hydrochloride (vitamin B1), riboflavin (vitamin B2),pyridoxine hydrochloride (vitamin B6), nicotinic acid and D-alpha-tocopheryl acid succinate. Preferably, the pharmaceutical composition further contains Dingpeng cream. According to the povidone-iodine pharmaceutical composition, the povidone-iodine solution and the various vitamin zinc tablets are combined to use, so that dual effects of prevention and treatment are realized; the povidone-iodinepharmaceutical composition is used for treating both cause and symptoms and accelerating wound healing and has a reliable curative effect. Meanwhile, by matching with the Dingpeng cream, the breedingof the oral pathogens is effectively inhibited, the oral environment is good and the wound is promoted to heal; the povidone-iodine pharmaceutical composition is used for effectively preventing oraldiseases from occurring. The invention provides an effective technical means for treating the skin and mucosa infection.

The invention provides a preparation method of a povidone-iodine solution and the povidone-iodine solution prepared by the method. According to the method provided by the invention, a stabilizing agent is added during the preparation reaction process, so that the stability of the prepared povidone-iodine solution can be effectively improved. Meanwhile, the method provided by the invention has the advantages that the process is simple; the control is easy; the large-scale equipment is not needed; the large-scale industrial production is easy; meanwhile, the povidone-iodine solution provided by the invention has the advantages of high effective iodine content in the solution, high stability and the like.

The invention relates to a povidone iodine solution and a preparation method thereof. 100 g of povidone iodine solution is mainly prepared from, by weight, 0.1-3 g of elementary substance iodine, 1-5g of PVP, 1-10 g of polyvinyl alcohol, 2-10 g of polyurethane, 0.1-5 g of sodium alginate, 0.2-5 g of organic acid, 5-35 g of surfactant, 1-3 g of plasticizer and the balance water and pH adjuster. The povidone iodine solution is safe, reliable, high in stability and good in film-forming effect, formed film is high in toughness and does not easily fall off, the drug efficacy is durable, the antibacterial effect is ensured, a lot of labor and drug application cost can also be saved at the same time, and the povidone iodine solution is suitable for large-scale dairy cattle breeding farms.

The invention belongs to the field of analytical chemistry, and relates to a method for determining the povidone content in a povidone iodine solution, particularly to an HPLC determination method for the povidone content in a povidone iodine aqueous solution. According to the HPLC determination method, a C18 chromatographic column is used, acetonitrile-water 5:95 is used as a mobile phase, and the povidone content in a povidone iodine aqueous solution is determined at a flow rate of 0.8 mL / min at an ultraviolet detection wave length of 205 nm through an ultraviolet detector. According to the present invention, the analysis determination results of the detected sample show that the HPLC determination method has advantages of convenience, rapidness, good accuracy and high sensitivity, is particularly suitable for the determination of the povidone content in the povidone iodine aqueous solution, and can improve the quality control and the medication safety of the povidone iodine liquid preparation.

The invention discloses a chitosan povidone-iodine solution and a manufacturing technologythereof. The raw material formula of the chitosan povidone-iodine solution comprises the following ingredients in percentage by weight: 0.2 to 1.3 percent of chitosan quaternary ammonium salt; 1 to 5 percent of vinylpynolidone; 0.1 to 0.9 percent of potassium iodide; 34 to 57.6 percent of 0.1M citric acid monohydrate solution; 36 to 61.2 percent of 0.2M anhydrous disodium hydrogen phosphate solution; the 0.1M citric acid monohydrate solution and the 0.2M anhydrous disodium hydrogen phosphate solution are both aqueous solutions prepared according to certain ratios. According to the chitosan povidone-iodine solution and the manufacturing technologythereof, the solution is simple in process, the product quality is excellent, no hazardous gas and liquid are discharged, and the product has the characteristics of being broad in spectrum, high in efficiency, long-acting, free of toxicity, stimulation and corrosiveness, and the like, and has good killing effects on bacteria, viruses and fungi.