Fuyanjing oral preparation and preparation method thereof

An oral preparation, Fuyanjing technology, applied in the field of pharmaceutical preparations, can solve the problems of poor long-term stability and disintegration, poor moisture resistance and instability of the original capsule, and achieves improved disintegration and dissolution, reduced Potential safety hazards and improved efficacy

Active Publication Date: 2013-06-26
杨文龙
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0022] Some active ingredients in this product are unstable under wet conditions, and the original capsule has poor moisture resistance. After changing to tablet coating, the long-term stability and disintegration of the preparation will become poor, and the stability of the preparation needs to be improved

Method used

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  • Fuyanjing oral preparation and preparation method thereof
  • Fuyanjing oral preparation and preparation method thereof
  • Fuyanjing oral preparation and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0038] [Prescription] Angelica 250g, Caulis Spatholobus 375g, Bitter Scrophulariae 250g, Didancao 375g

[0039] 菥蓂375g Finger peach 500g Hengjing mat 375g Double-faced needle 375g

[0040] Persimmon leaves 375g

[0041] [Preparation method] The nine medicinal materials in the prescription are decocted twice with water, the first time is 3 hours, the second time is 2 hours, the decoction is combined, filtered, and the filtrate is concentrated into a thick paste (relative density 1.28, temperature 90°C), mixed Uniformly, dry, pulverize, press into 1000 pieces, coat, pack, and get ready.

Embodiment 2

[0043] [Prescription] Angelica 250g, Caulis Spatholobus 375g, Bitter Scrophulariae 250g, Didancao 375g

[0044] 菥蓂375g Five-finger peach 500g Horizontal sutra mat 375g Two-faced needle 375g

[0045] Persimmon leaves 375g

[0046] [Preparation method] In the prescription, 125g of bitter scrophulariaceae is crushed into fine powder, and the remaining bitter scrophulariaceae and other eight-flavored medicinal materials such as angelica are decocted twice, the first time is 3 hours, the second time is 2 hours, and the decoction is combined. Filtrate, concentrate the filtrate into a thick paste (relative density 1.28, temperature 90°C), add bitter scrophulariae fine powder, mix well, dry, crush, press into 1000 pieces, coat, pack, and obtain.

Embodiment 3

[0048] [Prescription] Angelica 250g, Caulis Spatholobus 375g, Bitter Scrophulariae 250g, Didancao 375g

[0049] 菥蓂375g Five-finger peach 500g Horizontal sutra mat 375g Two-faced needle 375g

[0050] Persimmon leaves 375g

[0051] [Preparation method] The nine medicinal materials in the prescription are decocted twice with water, the first time is 3 hours, the second time is 2 hours, the decoction is combined, filtered, and the filtrate is concentrated into a thick paste (relative density 1.28, temperature 90°C), mixed homogeneously, add 5 g of polyethylene glycol 4000 dissolved in 500 ml of 95% ethanol, mix uniformly in equal increments, dry, granulate, press into 1000 tablets, coat, pack, and obtain final product.

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Abstract

The invention provides a fuyanjing oral preparation and a preparation method thereof. Chinese angelica, caulis spatholobi, picria fel-terrae, elephantopus scaber, thlaspi arvense, radix fici simplicissimae, membranaceous beautyleaf root, shinyleaf pricklyash root and persimmon leaves are taken as raw materials, the autologous characteristic of a Chinese herbal compound prescription is utilized, and component dissolution is realized by compatibility of poly vinyl alcohol 4000, so that the fuyanjing oral preparation is prepared, disintegration and dissolution are avoided, potential safety hazards are reduced, and pharmaceutical effect is improved.

Description

technical field [0001] The invention relates to an oral preparation of Fuyanjing and a preparation method thereof, belonging to the field of pharmaceutical preparations. Background technique [0002] Fuyanjing Tablets is based on a dosage form of Fuyanjing Capsules in the 2000 edition of the Chinese Pharmacopoeia. It has the functions of clearing away heat and dampness, regulating menstruation and stopping leukorrhea, and is used for irregular menstruation and dysmenorrhea caused by damp accumulation and heat knot; adnexitis, pelvic inflammatory disease, endometritis. The preparation process of this product is basically the same as that of capsules, and the active ingredients are retained during the preparation process. On the basis of the quality standards of the original capsules, the determination of the content of lianthin chloride in liangmianzhen is added, which improves the quality standard level and achieves safety, Effective, controllable and stable. [0003] (1) ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/808A61K47/32A61K47/34A61K47/36A61K47/38A61P15/00
Inventor 杨文龙
Owner 杨文龙
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