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Medicinal cake and moxa cone for treating hyperlipemia, and moxibustion method through medicinal cake

A technology for hyperlipidemia and drug separation cake, which is applied in the directions of pharmaceutical formulation, drug delivery, drug combination, etc., can solve the problem that the length or height of moxa sticks and moxa cones are not unified, there is no authoritative reference basis, and it is not conducive to drug separation. The development of cake moxibustion and other problems can improve people's health and quality of life, promote the intervention of endothelial cell inflammatory response, and delay the formation of atherosclerosis.

Inactive Publication Date: 2013-07-03
HUNAN UNIV OF CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

(3) The operation of moxibustion cannot be unified, such as the application of moxibustion, the time limit of each treatment, the length of the course of treatment, etc.
In addition, the length or height of moxa sticks and moxa sticks are not uniform
(4) There is no authoritative reference basis for the selection of acupoints, and it is not conducive to the further development of herbal cake-partitioned moxibustion

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0016] Methods: 75 New Zealand big-eared white rabbits were fed with high-fat diet and immune injury method to establish rabbit AS model. Then they were randomly divided into 5 groups, 15 rats in each group, namely: blank group (blank control group); model group (AS model group); direct moxibustion group (AS model + moxa cone direct moxibustion); herbal cake-partitioned moxibustion group (AS model group). model + herbal cake-partitioned moxibustion); Western medicine group (AS model + atorvastatin). Enzyme method was used to measure the changes of TC and TG contents after intervention; colorimetric method was used to measure the changes of LDL and HDL contents after intervention; electrophoresis method was used to measure the changes of Apo-A and Apo-B contents after intervention. Results: Herbal cake-partitioned moxibustion, direct moxibustion and western medicine could all reduce the contents of TC and LDL in rabbit AS serum (P<0.01 or P<0.05), and reduce the contents of TG ...

Embodiment 2

[0018] Methods: Rabbit AS model was established by feeding with high-fat diet and immune injury. Seventy-five New Zealand big-eared white rabbits were randomly divided into 5 groups, 15 in each group, namely the blank group (blank control group), the model group (AS model group), the direct moxibustion group (AS model + direct moxibustion with moxa cone), and Herbal cake moxibustion group (AS model + herbal cake-partitioned moxibustion), western medicine group (AS model + atorvastatin). Detection of rabbit aortic endothelial cells after 16 weeks of treatment Express. Results: model group aortic endothelial cells The protein expression of the group was significantly lower than that of the blank group, western medicine group and herbal cake-partitioned moxibustion group, and there was statistical significance (P The average gray value decreased (P0.05). Conclusion: Herbal cake-partitioned moxibustion can activate aortic endothelial cells in AS rabbits The expression of th...

Embodiment 3

[0020] Method: Combining self-prepared cakes and moxa stick moxibustion, moxibustion was applied to Juque, Tianshu, Fenglong, Xinshu, Ganshu, Pishu and other acupoints to treat 41 patients with hyperlipidemia, and 36 patients were treated with Hawthorn orally. The Jingjiangzhi Tablets group was the control. Results: Herbal cake-partitioned moxibustion could make serum TCH (4.920±2.106), TG (2.308±2.270), LDL-C (2.199±1.733), and plasma TXB2 (88.82±46.50), 6-k-PGF1α (520.05±287.65 ) decreased significantly (P<0.05~0.01), and HDL-C (2.373±1.524) tended to increase. Conclusion: Herbal cake-partitioned moxibustion can regulate lipid metabolism in the body, and has a certain effect on the prevention and treatment of hyperlipidemia, atherosclerosis and the cardiovascular and cerebrovascular diseases caused by it.

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Abstract

The invention discloses a medicinal cake for treating hyperlipemia, and a moxibustion method through the medicinal cake. The medicinal cake can significantly lower lipid, treat and protect the injured vascular endothelial cells (intervention to inflammation), promote the outflow of macrophage cholesterol and interfere endothelial inflammation through activating expression of peroxisome proliferator activated receptors in atherosclerotic aortic endothelial cells and smooth muscle cells, so as to delay the formation of atherosclerosis. Therefore, the moxibustion method through the medicinal cake provides important reference to clinical rational use of acupuncture to treat the disease, also improves the clinical efficacy of acupuncture, gives full play to the role and benefits of acupuncture, enables more people to interfere and prevent generation and development of the disease through acupuncture treatment to improve people's health and quality of life, protect human health as an important requirement, and has an important application prospect and scientific value.

Description

technical field [0001] The invention belongs to the technical field of acupuncture and moxibustion of traditional Chinese medicine, and in particular relates to a moxibustion method for hyperlipemia with medicine cake, moxa cone and medicine cake. Background technique [0002] Herbal cake-partitioned moxibustion, as a method of acupuncture and moxibustion, has been favored by many medical practitioners and researchers since ancient times. Its clinical efficacy is undeniable, but there are still the following problems that need to be standardized and optimized. (1) There is no authoritative reference for drug compatibility and drug composition. Most researchers organize prescriptions by themselves, and the randomness is too large, which will not be conducive to deeper exploration. (2) The production of medicines or medicine cakes cannot be unified, such as thickness, diameter, and weight are different, but they are collectively referred to as "one strong", so they should be ...

Claims

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Application Information

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IPC IPC(8): A61K36/9066A61K36/282A61K9/00A61P3/06A61H39/06
Inventor 常小荣严洁刘密李铁浪岳增辉郁保生张国山杨舟石佳谢辉
Owner HUNAN UNIV OF CHINESE MEDICINE
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