Traditional Chinese medicine composition

A technology of composition and natural medicine, which is applied in the direction of drug combination, antineoplastic drugs, pharmaceutical formulations, etc., to achieve obvious synergistic effects, increased inhibitory effects, and good synergistic effects

CN103223084AInactive Publication Date: 2013-07-31张宗升
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Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
Publication Date
2013-07-31
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention relates to a natural pharmaceutical composition, preparation method thereof and the usage in preparing an attenuated synergistic medicament in cancer chemotherapy, wherein the natural pharmaceutical composition consists of decoction condensed extract product of dried orange peel and yam, nobiletin, ethanol extract product of yam and yam polysaccharide in a proportion of (4-5):(2-8):(1-3):(5-9). The composition has good curative effect to cancer chemotherapy related diarrhoea and increases effect to cancer chemotherapy.
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Description

technical field

[0001] The present invention relates to a kind of natural medicine composition, more specifically relate to a kind of natural medicine composition that is made up of tangerine peel yam water decoction concentrated extract, nobietin, yam ethanol extract and yam polysaccharide, the preparation of this natural medicine composition The method and the use of the natural medicine composition in preparing medicines for reducing cancer chemotherapy-related diarrhea and synergizing cancer treatment. Background technique

[0002] Malignant tumor is one of the main diseases that endanger human survival and health at present. Its treatment methods include surgery, chemotherapy, radiotherapy, and traditional Chinese medicine treatment, and the effect of chemotherapy on tumors is particularly prominent. Chemotherapy drugs, whether used alone or in combination, can cause toxic and side effects such as diarrhea in patients. Diarrhea after tumor chemotherapy is also called ch...

Examples

Embodiment approach

[0034] The first step: preparation of various extracts

[0035] (1) Preparation of tangerine peel yam decoction concentrated extract

[0036] Take tangerine peel and yam according to the compatibility ratio of 1:1 or 1-4:1, soak in 10 times the amount of distilled water for 1 hour, heat and decoct on an electric stove with asbestos net for 1 hour, filter with silk cloth, save the filtrate, and add the dregs 6 times of distilled water, soaking, decocting, and filtering in the same way, mixing the two filtrates, heating and concentrating to a small volume, filtering with an ultrafiltration membrane, and drying under reduced pressure at 70°C for 36 hours in a vacuum drying oven to obtain a brown-yellow powder.

[0037] (2) Preparation of Nobiletin

[0038]Take the dried tangerine peel medicinal material, coarsely crush, sieve, reflux and extract 20 times the amount of petroleum ether for 5 times, 6 hours each time, combine the petroleum ether extract, recover the petroleum ether...