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Application of ampelopsin in preparation of vascular endothelial cell protection health food or drugs

A technology of snake grapevine and health food, which is applied in the field of snake grapevine in health food and pharmaceuticals, and can solve the problems that there is no snake grapevine

Inactive Publication Date: 2013-08-21
任启生 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But so far, there is no report on the application of staphylophyll in the preparation of health food and medicine for protecting vascular endothelial cells

Method used

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  • Application of ampelopsin in preparation of vascular endothelial cell protection health food or drugs
  • Application of ampelopsin in preparation of vascular endothelial cell protection health food or drugs
  • Application of ampelopsin in preparation of vascular endothelial cell protection health food or drugs

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] The snake grapes were taken, and conventional extraction methods were used to extract and purify the snake grapes, and then pack them into powder injection ampoules or injections of 0.4g / bottle.

Embodiment 2

[0025] Get vine tea and extract the staphylophyllin extract conventionally, without purification, after content determination, get 340g staphylophyllin extract, add 30g vitamin E, 30g vitamin C, add auxiliary material according to the conventional method, granulate, mix, Sieve, add glidant magnesium sulfate, talcum powder, process into tablet according to tablet routine production process, make staphylophyll tablet, each tablet contains staphylocoxine 200mg.

Embodiment 3

[0027] Take 10kg of sucrose grapes, extract twice by conventional ethanol extraction method, combine the ethanol extracts and concentrate to a clear paste with a relative density of 1.35-1.38, add an appropriate amount of sucrose powder, mix well, and make granules.

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PUM

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Abstract

The present invention discloses an application of ampelopsin in preparation of vascular endothelial cell protection health food or drugs, wherein purified ampelopsin or an unpurified ampelopsin-containing extract can be adopted to prepare a pharmaceutically acceptable oral formulation, a pharmaceutically acceptable injection formulation or a pharmaceutically acceptable external application formulation, and the ampelopsin provides a vascular endothelial cell protection function through lipid peroxidation reduction, oxidative damage resistance and other effects so as to prevent and treat cardiovascular and cerebrovascular diseases caused by vascular endothelial cell damage, wherein the diseases comprise atherosclerosis, high blood pressure, heart and cerebral thrombosis, and the like.

Description

[0001] Research areas: [0002] The present invention relates to the application of staphyloin in the fields of health food and pharmacy, in particular to the application of staphylocin in the preparation of health food and medicine for protecting vascular endothelial cells. Background technique: [0003] Vascular endothelial cells (VEC) are a single layer of flat cells lining the inner surface of the cardiovascular vessel. Vascular endothelial cells not only have the functions of selective permeability, anti-thrombosis, regulation of vascular tension, promotion of capillary formation and production of blood cell adhesion factors, but also the source and target organ of various vasoactive substances, cytokines and growth factors. [0004] The injury of vascular endothelial cells is closely related to various cardiovascular diseases (such as atherosclerosis, hypertension, thrombosis, etc.). Taking thrombus as an example, endothelial cells have an antithrombotic effect under p...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/352A61P7/02A61P9/10A61P9/12A23L1/30
Inventor 任启生宋新荣
Owner 任启生
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