A three-dimensional biological structure printing device and method

A technology of three-dimensional biological and printing devices, which is applied in the fields of biomedical engineering and tissue engineering, and can solve problems such as failure to achieve expected results

Active Publication Date: 2015-08-26
ZHEJIANG UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Researchers have proposed many solutions to solve the shortage of donor organs, but none of them have achieved the expected results. Until the 1980s, scientists first proposed tissue engineering technology. Its essence is to combine living cells with the matrix in a certain way. Combining materials or scaffolds to create new tissues, tissue engineering and regenerative medicine are expected to completely solve the problem of donor organ shortage, repair or replace damaged organs

Method used

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  • A three-dimensional biological structure printing device and method
  • A three-dimensional biological structure printing device and method
  • A three-dimensional biological structure printing device and method

Examples

Experimental program
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Embodiment Construction

[0046] Such as figure 1 , figure 2 , image 3 , Figure 4 As shown, a three-dimensional biological structure printing device includes: an execution unit for printing and generating a three-dimensional biological structure, a control unit for controlling the printing operation of the execution unit, and a detection unit.

[0047] Among them, the execution unit includes a nozzle 18 that sprays bio-ink, a working panel 22 that supports the three-dimensional biological structure, a liquid supply system connected to the nozzle 18, and three-dimensional adjustments to the position of the nozzle or the working panel to meet the three-dimensional biological structure printing requirements. mechanism.

[0048] The nozzle 18 can be a piezoelectric nozzle, and the driver can squeeze the nozzle to realize the ejection of bio-ink. Generally, the driver can choose an existing structure, which will not be described in detail here. The nozzle 18 is fixed on the nozzle fixture 14, and th...

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Abstract

The invention discloses a printing device for a three-dimensional biological structure. The printing device comprises an execution unit with a liquid supply system, and a control unit, wherein the liquid supply system comprises an air compressor, an air capacitor communicated with an air outlet of the air compressor, and a liquid storage tank; a liquid outlet of the liquid storage tank is communicated with a liquid inlet of a spray head; a liquid inlet of the liquid storage tank is communicated with an air outlet of the air capacitor; a pressure reducing valve is arranged on a pipeline between the liquid storage tank and the air capacitor; the opening degree of the pressure reducing valve can be adjusted, and thus liquid drops at a spray nozzle of the spray head are enabled to not drop off; the height of the liquid storage tank can be adjusted, and thus the lowest end of a liquid level at the spray nozzle of the spray head is leveled with the spray nozzle of the spray head. The printing device disclosed by the invention can be widely applied to forming of biological scaffolds with various shapes, can be used for printing vascular structures and has the advantages of high printing precision, simpleness in operation, low cost and the like. Due to the adoption of the design of a replaceable clamp, a replaceable working face and a replaceable Z-shaped mounting plate, the printing device can be used for printing biological structures with different sizes and different tissue materials.

Description

technical field [0001] The invention relates to the technical fields of biomedical engineering and tissue engineering, in particular to a three-dimensional biological structure printing device and method. Background technique [0002] With the development of society, various traffic accidents, natural disasters caused damage to human organs or congenital organ damage caused many people's lives to be threatened. The traditional repair method is autologous tissue transplantation. Although this method can obtain satisfactory effect, but it sacrifices their own healthy tissues, so many people are waiting in line for donor organs in hospitals, but due to the extremely limited source of donor organs, the number of people who need organs far exceeds the number of donor organs, and many patients have not yet waited for donor organs. Body organs are already dead. [0003] Therefore, the extreme shortage of donor organs for organ transplantation has become a major problem faced by me...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61F2/02A61F2/06A61F2/07
Inventor 傅建中邵惠锋贺永高庆
Owner ZHEJIANG UNIV
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