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Cough medicine and preparation method thereof

The technology of antitussive medicine and Pinellia fragrans is applied in the field of antitussive medicine composition and preparation thereof, which can solve the problems of delayed recovery of patients, dry mouth and constipation of patients, etc., and achieve the effects of improvement of physical signs and remarkable effect.

Active Publication Date: 2014-02-26
CHONGQING HOLLEY PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In this way, while treating cough, it will also cause the patient to suffer from symptoms such as dry mouth and constipation, which will delay the recovery of the patient and even cause other febrile diseases.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0036] Put 3.6kg perilla leaves, 2.1kg Fangfeng, 5.4kg Houttuynia cordata, 3.6kg forsythia, and 1.8kg bitter almonds into the volatile oil extractor to extract the volatile oil contained therein; Ephedra, 5.0kg Scutellaria baicalensis, 2.9kg Platycodon grandiflorum, 2.5kg Pinellia chinensis, 2.1kg aster, 1.1kg poppy shell, 1.8kg licorice mixed with 60% ethanol aqueous solution for 2 reflux extractions, the amount of each ethanol aqueous solution It is 175kg, and the extraction time is 2 hours each time; the extracted solution is left to stand for 48 hours, and the supernatant is concentrated under reduced pressure to obtain an extract, which is prepared as a product.

Embodiment 2

[0038] Put 1.5kg perilla leaves, 1.1kg Fangfeng, 2.2kg Houttuynia cordata, 2.4kg forsythia, 1.5kg bitter almonds into the volatile oil extractor and use steam to extract the volatile oil contained therein; Ephedra, 2.0kg Scutellaria baicalensis, 1.3kg Platycodon grandiflorum, 0.9kg Pinellia chinensis, 1.1kg aster, 0.7kg poppy shell, 1.1kg licorice mixed with 70% ethanol aqueous solution for 3 times of reflux extraction, each time the amount of ethanol aqueous solution It is 118.4kg, and the extraction time is 3 hours each time; the extracted solution is allowed to stand for 72 hours, and the supernatant is concentrated under reduced pressure to obtain an extract, which is prepared as a product.

Embodiment 3

[0040] Put 1.2kg perilla leaves, 1.2kg Fangfeng, 2.0kg Houttuynia cordata, 2.0kg forsythia, 1.2kg bitter almonds into the volatile oil extractor and use water vapor to extract the volatile oil contained in it; Ephedra, 2.0kg Scutellaria baicalensis, 1.2kg platycodon, 0.8kg Pinellia chinensis, 0.8kg aster, 0.8kg poppy shell, and 1.2kg licorice are mixed with 90% ethanol aqueous solution for 4 times of reflux extraction, each time the amount of ethanol aqueous solution It is 156.1kg, and the extraction time is 2 hours each time; the extracted solution is left to stand for 72 hours, and the supernatant is concentrated under reduced pressure to obtain an extract, which is prepared as a product.

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PUM

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Abstract

The invention relates to a cough medicinal composition and a preparation method thereof, and aims to provide a cough medicine which can be used for treating exterior cold and interior heat type cough and has a good treatment effect and a preparation method thereof. The cough medicine comprises scutellaria baicalensis, 10-15 parts by weight of fructus forsythiae, herba houttuyniae, processed pinellia tuber, aster, pericarpium papaveris, ephedra, semen armeniacae amarum, liquorice, platycodon grandiflorum, perilla leaf and divaricate saposhnikovia root. The preparation method comprises the following steps: putting the weighed perilla leaf, the divaricate saposhnikovia root, the herba houttuyniae, the fructus forsythiae and the apricot kernel in a volatile oil extractor to extract volatile oil; mixing the remained decoction dreg, the scutellaria baicalensis, platycodon grandiflorum, processed pinellia tuber, aster, pericarpium papaveris and liquorice, and performing reflux extraction on the mixture by using an organic solvent; standing the extracted solution, concentrating the supernate into an extract, and preparing the product. The cough medicine is remarkable in total curative effect in treating exterior cold and interior heat type cough, traditional Chinese medicinal curative effect and effects of relieving cough and reducing sputum to relieve asthma, and can be used for remarkably improving abnormal hemogram, chest radiograph and sign of patients on acute bronchitis and the acute attack of chronic bronchitis.

Description

technical field [0001] The invention relates to an antitussive composition and a preparation method thereof. Background technique [0002] In traditional Chinese medicine, cough is a symptom of vocalization and phlegm caused by exogenous pathogenic factors and internal injuries of internal organs affecting the lungs. Cough means there is sound without phlegm, and the lung qi is damaged but not clear; cough is silent but with phlegm, and phlegm is caused by dampness of the spleen. Cough is said to have phlegm and sound, which is caused by injury to the lungs and dampness of the spleen, and coughing is also called coughing. That is to say, the cough is caused by exogenous evils invading the lungs or internal injuries to the viscera or involving the lungs. [0003] The diseases that cause cough can also be divided into yin and yang, that is, cold and heat. For example, when treating a cough caused by wind and cold, cold and warm should be removed, while for a cough caused by ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8888A61P11/14A61P11/00
Inventor 刘永源罗晓江欧阳敏杨再辉黄元军刘晓东
Owner CHONGQING HOLLEY PHARMA
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