Fixing device for mouse caudal intravenous injection

Abstract

The invention discloses a fixing device for mouse caudal intravenous injection. The fixing device comprises two baffle assemblies arranged symmetrically, a rotatable base plate, a fixing clamp and a rotatable base plate driving shaft. The two baffle assemblies are arranged on the rotatable base plate, each baffle assembly comprises a side wall plate, a rear side baffle, a head fixing plate and a tail fixing plate, one end of each rear side baffle is fixedly connected with one side wall plate, the other end of the rear side baffle is fixedly connected with one tail fixing plate, and a neck positioning groove is formed in each head fixing plate. The neck positioning grooves in the head fixing plates in the two the baffle assemblies are matched to clamp the neck of a mouse and limit the head of the mouse, the tail fixing plates in the two baffle assemblies are matched to limit the tail of the mouse, and a channel for the tail of the mouse to penetrate through is formed in the lower portion of each tail fixing plate. The fixing clamp comprises a fixing clamp baffle, a mouse tail clamp and a fixing clamp clamping groove, and the fixing clamp clamping groove is respectively connected with the rear side baffles in the two baffle assemblies in an inserted mode. The fixing device for mouse caudal intravenous injection is convenient to operate and used for mouse caudal intravenous injection in batch, and can improve efficiency.

Description

technical field [0001] The invention relates to a test animal fixation device, in particular to a mouse tail vein injection fixation device and a fixation device capable of fixing mice in batches for tail vein injection. Background technique [0002] Tail vein injection of mice is a commonly used injection method in pharmacology, toxicology, and drug efficacy tests, and it is also one of the necessary skills in medical research. However, because mice are active by nature and their tail veins are relatively thin, it is necessary to use a fixation device to fix the mice. [0003] The current mouse immobilization device mainly has the following problems: [0004] 1. Fixing by inserting the baffle, the operation is difficult and time-consuming. [0005] 2. The push baffle is adopted, although the inconvenience in the insertion process is eliminated, but the mouse will curl up into a ball during the push baffle, and if it rolls, it will cause the tail to be pulled, which brings...

AI Technical Summary

Problems solved by technology

[0004] 1. It is difficult to operate and takes a long time to fix by inserting the baffle

[0005] 2. Using the push baffle, although the inconvenience during the insertion process is eliminated, the mouse will curl up into a ball during the process of pushing the baffle, and if it rolls, it will cause the tail to be pulled, which brings inconvenience to the operation

[0006] 3. The suction cup is fixed on the fixed plate through threads to ensure the firmness of the fixing device, but the suction function will completely disappear when the suction cup hardens over time, the thread is easy to wear, and the operation is complicated and time-consuming

[0007] 4. A single mouse is used for fixation, and a large number of mice cannot be fixed at one time.

Since most experiments require 8-10 mice per group, the process of repeated fixation-injection-removal of fixation device-refixation takes a lot of time

[0008] 5. Due to the small size of the mouse, the fixer is small, and it is not possible for multiple people to cooperate in the fixation and experiment, which is not conducive to a clear division of labor

[0009] 6. Hard plastic materials or steel mesh are often used, which will increase the stress of the mice when fixing the mice and affect the experimental results.

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