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A method for increasing the content of isofeskolin in Coleus sage

A technology of isophoreskolin and medicinal materials, which is applied in the field of promoting the synthesis and accumulation of isophoreskolin, can solve the problem of low content of active ingredient isophoreskolin, and achieve simple and easy implementation, no impact on the environment, and equipment simple effect

Active Publication Date: 2018-10-12
湖北福人药业股份有限公司
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  • Summary
  • Abstract
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  • Claims
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AI Technical Summary

Problems solved by technology

Compared with the wild medicinal materials in Yunnan, the medicinal materials planted in Tongcheng County have no significant difference in pharmacognosy, chemical composition and pharmacology, but the content of the active ingredient isophoreskolin is relatively low

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0014] Bring the freshly excavated Coleus spp. plants in the base back to the treatment workshop, and rinse the surface of the medicinal materials with sediment and other foreign objects with clean water. It was placed in ultraviolet A for irradiation, the irradiation intensity was 40W, the irradiation time was 12h, the temperature during the irradiation was 25°C, and the relative humidity was 90%. After irradiation, isorskolin was analyzed by high performance liquid chromatography (HPLC). The results showed that the content of isforskolin in the roots and rhizomes of Coleus serrata increased by 33.7% to 94.4% after irradiation.

Embodiment 2

[0016] The experiment was carried out in the same way as in Example 1, except that the ultraviolet B was irradiated, the irradiation intensity was 160W, the irradiation time was 12h, the temperature during the irradiation was 24°C, and the relative humidity was 90%. After testing, the content of isorskolin in the roots and rhizomes of Coleus serrata increased by 20%.

Embodiment 3

[0018] The apparatus and irradiation method of ultraviolet irradiation are as follows: Fix the ultraviolet lamp tube capable of emitting ultraviolet A or B on the iron or wooden bracket, place it about 80cm above the medicinal material, turn on the power supply, and turn on the ultraviolet lamp.

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Abstract

The invention relates to a method for increasing the content of isoforskolin in the coleus medicine, in particular to a method for promoting isoforskolin to be synthesized and accumulated by inducing the coleus medicine by utilizing ultraviolet light.

Description

technical field [0001] The invention relates to a method for increasing the content of isforskolin in Coleus serrata medicinal materials, in particular to a method for promoting the synthesis and accumulation of isforskolin by using ultraviolet rays to induce Coleus serrata medicinal materials. Background technique [0002] Coleus forskohlii (Wild.) Briq is derived from the Lamiaceae plant Coleus forskohlii (Wild.) Briq, which is produced in India, Nepal and other countries and my country's Yunnan Huize, Dongchuan and other places. Local folk are used to treat cough, palpitation, dizziness and other symptoms, with remarkable curative effect, known as "magic medicine". Modern pharmacological studies have shown that Coleus coleus extracts have obvious effects on bronchial asthma, congestive heart failure, and various tumors. Hubei Furen Pharmaceutical Co., Ltd. has developed the new traditional Chinese medicine "Coleus Capsule" with Coleus as the main raw material, which has ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/53
Inventor 余坤刘焱文叶晓川吴宇星李捷邹鹏程黄婕
Owner 湖北福人药业股份有限公司
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