Method and device for classifying white blood cells

A leukocyte classification and leukocyte technology, which is applied in the field of leukocyte classification methods and devices, and can solve problems such as inability to classify leukocytes

Active Publication Date: 2014-04-23
AVE SCI & TECH CO LTD
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Problems solved by technology

[0005] In view of this, in order to solve the problem that the existing white blood cell classification method cannot accurately classify white blood cells, the technical solution is as follows:

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  • Method and device for classifying white blood cells
  • Method and device for classifying white blood cells
  • Method and device for classifying white blood cells

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Embodiment Construction

[0043] The following will clearly and completely describe the technical solutions in the embodiments of the present invention with reference to the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only some, not all, embodiments of the present invention. Based on the embodiments of the present invention, all other embodiments obtained by persons of ordinary skill in the art without making creative efforts belong to the protection scope of the present invention.

[0044] see figure 1 , an embodiment of the present invention provides a leukocyte classification method, comprising:

[0045] Step 110: Stain the leukocytes in the blood sample to obtain a blood sample containing the stained leukocytes.

[0046] Step 120: Collect images of the leukocyte blood sample to obtain an image of the leukocyte blood sample.

[0047] Step 130: Segment various types of cells in the white blood cell blood sample image, and extract cell ...

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Abstract

The invention provides a method and a device for classifying white blood cells. The method comprises the following steps: dyeing the white blood cells in a blood sample to obtain a blood sample containing the dyed white blood cells; performing image acquisition on the white blood cell blood sample to obtain a white blood cell blood sample image; segmenting various cells of the white blood cell blood sample image, and respectively extracting cell morphology characteristic parameters of various cells; performing re-segmentation on various segmented cells to obtain a cell nucleus image and a cytoplasm and particle image; extracting color characteristic parameters of the cell nucleus image; extracting particle distribution characteristic parameters and color characteristic parameters of the cytoplasm and particle image; performing normalization on extracted characteristics; sending the normalized characteristics into a neural network classifier, identifying five types of cells in the white blood cells, and respectively working out the number of the five types of cells and the percentage of total white blood cell count. According to the method and the device for classifying the white blood cells provided by the invention, the white blood cells can be accurately classified.

Description

technical field [0001] The present invention relates to the field of cell classification, and more specifically relates to a white blood cell classification method and device. Background technique [0002] White blood cell differential is a medical test that counts white blood cells differently during blood microscopy. White blood cells in the blood include neutrophils, eosinophils, basophils, lymphocytes, and monocytes. In addition, myeloblasts are the progenitor cells or immature cells of granulocyte development, which will appear in the blood of certain patients, such as in the blood of leukemia patients. Myeloblasts are not classified as conventionally classified cells, and their components are basophilic It turns blue when dyed. The above-mentioned types of cells each have their own physiological functions, and leukocyte classification is an important indicator in environmental medicine research. [0003] The current white blood cell classification method is usually ...

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G06K9/00G06K9/34G06K9/46G01N15/00
Inventor 丁建文
Owner AVE SCI & TECH CO LTD
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