A drug for interventional treatment of uterine fibroids

A technology of uterine fibroids and drugs, which is applied in the field of drugs for interventional treatment of uterine fibroids, can solve problems such as skin pain, burning and acupuncture-like sensations, and achieve easy-to-accept, trauma-avoiding, and quick-acting effects

Active Publication Date: 2015-11-25
AFFILIATED HOSPITAL OF NANTONG UNIV
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Ultrasound-guided high-intensity focused ultrasound treatment of uterine fibroids can inactivate tumors, but patients have skin pain, burning and acupuncture-like sensations, backache and other adverse reactions and complications of varying degrees after surgery

Method used

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Embodiment Construction

[0024] Lauromacrogol belongs to polyoxyethylene lauryl ether compounds and is an internationally recognized sclerotherapy drug. It has long been used in the treatment of varicose veins of lower extremities and esophageal varicose veins in the world. After lauromacrogol is injected into the tumor, it can damage the vascular endothelium, promote thrombus formation, block blood vessels, and block the source of blood supply; especially after injection under the tumor capsule, a layer of dense fibrous tissue is gradually formed in the subcapsule, Cause vascular damage and permanent occlusion. Eventually, the tumor shrinks and gradually disappears. At present, there is no report in the world that intratumoral injection of lauromacrogol under ultrasound guidance in the treatment of uterine fibroids. At present, our hospital has been carried out as a routine project in clinical practice. Intratumoral injection of lauromacrogol under ultrasound guidance in the treatment of 580 cases of...

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Abstract

The invention provides a medicine for interventional treatment of uterine myoma. The medicine belongs to a polyoxyethylene lauryl alcohol ether compound, called lauromacrogol for short; after lauromacrogol is injected under the envelope of an uterine myoma body, a layer of fibre textures is formed in the lower layer of the envelope; blood vessels are injured and permanently occluded by the fibre textures, so that the uterine myoma body is reduced and gradually disappears; uterine myoma is subjected to interventional treatment by utilizing the medicine, so that the functions of an uterus can be intactly retained; in addition, fertilization is not influenced; operative wound and a series of post-operative complications are avoided; the effect of the medicine disclosed by the invention is comparable with operation in the aspect of symptom improvement; by means of interventional treatment of uterine myoma by utilizing the medicine, the medicine disclosed by the invention is small in wound, rapid in recovery, free from being in hospital and easy for patients to accept; compared with the traditional operative treatment, interventional treatment of uterine myoma by utilizing the medicine is simple and convenient; furthermore, blood transfusion is generally unnecessary; the medicine disclosed by the invention has the advantages of being minimally invasive, repeatable, accurate for locating, high in curative effect, rapid in effect, few in complications and the like and brings a good development prospect for clinical treatment of uterine myoma.

Description

technical field [0001] The invention relates to the innovative field of lauromacrogol application, in particular to a drug for interventional treatment of uterine fibroids. Background technique [0002] Uterine fibroids are the most common benign tumors in female reproductive organs. The incidence rate accounts for about 20%-25% of women of childbearing age. The traditional treatment method is surgical resection, which especially makes nulliparous patients lose their fertility. Psychological permanent damage. In recent years, there are mainly two types of minimally invasive treatment of uterine fibroids, ie, vascular and non-vascular interventional therapy. [0003] Vascular access interventional therapy adopts uterine artery catheterization and embolization. Although it can block the blood supply of fibroids and achieve the purpose of shrinking fibroids, the technique is complicated, and the operation must be carried out under X-ray monitoring and radiation. People over 45...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/77A61P35/00
Inventor 谢阳桂
Owner AFFILIATED HOSPITAL OF NANTONG UNIV
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