A kind of pharmaceutical composition for treating myocardial ischemia and its preparation method and application

A technology of myocardial ischemia and composition, which is applied in the field of medicine, can solve the problems of inconvenient use for patients, poor quality controllability, and backward dosage forms, and achieve the effects of no toxic side effects, simplified prescriptions, and remarkable effects

A technology of myocardial ischemia and composition, which is applied in the field of medicine, can solve the problems of inconvenient use for patients, poor quality controllability, and backward dosage forms, and achieve the effects of no toxic side effects, simplified prescriptions, and remarkable effects

CN103800482BInactive Publication Date: 2015-08-12李兵晖
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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0015] Prescription: Dangshen 30g, Wang Buliuxing 15g, Panax notoginseng 35g

[0016] Peach kernel 15g Evening primrose 20g Divine Comedy 15g

[0017] Preparation method: Weigh the six traditional Chinese medicines of Codonopsis pilosula, Wang Buliuxing, Panax notoginseng, peach kernel, evening primrose, and divine comedy according to the above formula ratio, add 8 times the amount of water to it, decoct three times, 1.5 hours each time, combine Decoction, filter, concentrate the filtrate into a clear paste (80°C) with a relative density of 1.05-1.15, add ethanol until the alcohol content is 60% (v / v), stir, let stand for 12 hours, filter, and decompress the filtrate Recovery of ethanol, too.

Embodiment 2

[0019] Recipe: Dangshen 50g, Wang Buliuxing 20g, Panax notoginseng 20g

[0020] Peach kernel 30g, evening primrose 30g, divine comedy 5g.

[0021] Preparation method: Weigh the six traditional Chinese medicines of Codonopsis pilosula, Wang Buliuxing, Panax notoginseng, peach kernel, evening primrose, and Shenqu according to the above formula ratio, add 15 times the amount of water to it, decoct three times, 2.5 hours each time, combine Decoction, filter, concentrate the filtrate into a clear paste (80°C) with a relative density of 1.05-1.15, add ethanol until the alcohol content is 80% (v / v), stir, let stand for 24 hours, filter, and depressurize the filtrate Recovery of ethanol, too.

Embodiment 3

[0023] Recipe: Dangshen 40, Wangbuliuxing 20, Sanqi 25

[0024] Peach Kernel 20 Evening Primrose 25 Divine Comedy 10.

[0025] Preparation method: Weigh the six traditional Chinese medicines of Codonopsis pilosula, Wang Buliuxing, Panax notoginseng, peach kernel, evening primrose, and divine comedy according to the above-mentioned composition ratio, add 12 times the amount of water to it, decoct three times, 2 hours each time, combine Decoction, filter, concentrate the filtrate into a clear paste (80°C) with a relative density of 1.05-1.15, add ethanol until the alcohol content is 70% (v / v), stir, let stand for 18 hours, filter, and decompress the filtrate Recovery of ethanol, too.

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Abstract

The invention belongs to the field of medicines, specifically relates to a pharmaceutical composition for treating myocardial ischemia, and particularly relates to a traditional Chinese medicine composition for treating the myocardial ischemia and a preparation method of the traditional Chinese medicine composition. The pharmaceutical composition is prepared from the following traditional Chinese medicine materials in parts by weight: 30-50 parts of codonopsis pilosula, 10-30 parts of vaccaria segetalis, 20-35 pars of panax pseudoginseng, 15-30 parts of semen persicae, 15-35 parts of oenothera biennis and 5-15 parts of medicated leaven. The pharmaceutical composition has simple components, is safe, effective and simple in preparation process, does not have toxic or side effects, is high in patient compliance, and has good development and application prospects.

Description

Technical field [0001] The invention is a pharmaceutical field, which involves a pharmaceutical composition and preparation methods and applications that treat myocardial ischemia. Background technique [0002] With the aging of the social population and the changes in human diet structure, the incidence of cardiovascular disease has a significant increase in the world, which seriously threatens human health.Among them, ischemic heart disease is one of the most common and most harmful cardiovascular diseases in the clinic. The clinical manifestations are mainly myocardial ischemic symptoms such as angina pectoris and myocardial infarction.With the development of modern medicine, myocardial ischemia has developed rapidly in prevention, diagnosis, and treatment. However, due to its many complications and complicated mechanisms, and the limitations of the treatment of drugsEssenceDrugs such as nitrate, calcium channel blockers, β receptor blockers have significant effects on the tre...

Claims

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Application Information

Patent Timeline
12 Aug 2015
Publication
CN103800482B
IPC
A61K36/736; A61K9/16; A61K9/20; A61K9/48; A61K9/14; A61P9/10
Inventors
李兵晖; 马学玉