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Anthelmintic and preparation method thereof

A drug and product technology, applied in the field of pet medicine, can solve the problem of low gastrointestinal absorption rate, achieve high anthelmintic activity, and strong effect of killing insect eggs

Inactive Publication Date: 2014-07-23
SHENZHEN REDRAY BIOTECHNOLOGY CORP LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] For pet anthelmintic drugs, simple fenbendazole and benzoxazole imitate anthelmintic drugs have a broad anthelmintic spectrum but a low gastrointestinal absorption rate. In most clinical cases, praziquantel’s main role is to repel tapeworms. But generally it needs to be taken on an empty stomach

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] The total amount of raw material is 100 g. Among them, fenbendazole 83.3g, praziquantel 16.7g.

[0026] Preparation Process:

[0027] (1) Fenbendazole and praziquantel are weighed according to the formula ratio and put into the extraction tank;

[0028] (2) Weigh 800 g of water whose weight is 8 times the sum of all components in step (1) and add it to the extraction tank, and continue to boil for 2 hours;

[0029] (3) the product obtained in step (2) is filtered out of the filtrate from the extraction tank, and the filtrate is for subsequent use;

[0030] (4) Weigh 600 g of water whose weight is 6 times the sum of all components in step (1) and add it to the extraction tank of step (3), and continue to boil for 1.3 hours;

[0031] (5) The product obtained in step (4) is filtered out of the filtrate from the extraction tank, and the filtrate is mixed with the filtrate obtained in step (3), left to stand for 2 hours, and the upper clear liquid is obtained for subseque...

Embodiment 2

[0038] The total amount of raw material is 100 g. Among them, fenbendazole 87.2g, praziquantel 12.8g.

[0039] The preparation process is the same as in Example 1.

Embodiment 3

[0041] The total amount of raw material is 100 g. Among them, fenbendazole 84.2g, praziquantel 15.8g.

[0042] The preparation process is the same as in Example 1.

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PUM

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Abstract

The invention discloses an anthelmintic for pets and a preparation method thereof. The anthelmintic disclosed by the invention is prepared from the following components: 83.3-87.2% of fenbendazole and 12.8-16.7% of praziquantel. The invention further provides the preparation method of the anthelmintic. The components are matched according to a specific proportion; the fenbendazole is wide in anthelmintic spectrum; the praziquantel has low toxicity to dogs, cats and the like; conversion products of the fenbendazole and the praziquantel can effectively interfere transportation of glucose by polypides in dogs and cats; the fenbendazole and the praziquantel are matched according to a specific proportion, so that the anthelmintic can take effect rapidly and is unnecessary to take on an empty stomach; in addition, the polypide-repelling degree is relatively thorough.

Description

technical field [0001] The invention relates to the field of medicine for pets, in particular to an anthelmintic medicine. Background technique [0002] For pet anthelmintic drugs, simple fenbendazole and benzoxazole imitate anthelmintic drugs have a broad anthelmintic spectrum but low gastrointestinal absorption rate. In most clinical cases, the main function of praziquantel is to repel tapeworms. But generally it needs to be taken on an empty stomach. Contents of the invention [0003] The object of the present invention is to provide an anthelmintic medicine for expelling various worms in pets, which has a wide repelling spectrum, complete effect of repelling insects and does not need to be taken on an empty stomach. [0004] According to one aspect of the present invention, a kind of deworming medicine is provided, configured according to the following mass percentage: [0005] Fenbendazole 83.3-87.2%; [0006] Praziquantel 12.8 ~ 16.7%. [0007] Preferably, in som...

Claims

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Application Information

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IPC IPC(8): A61K31/4985A61K9/20A61P33/10A61K31/4184
Inventor 王军军包金旺
Owner SHENZHEN REDRAY BIOTECHNOLOGY CORP LTD
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