Epoxidized styrene-isoprene-styrene block copolymer medical patch and preparation method thereof

A technology of epoxidizing styrene and styrene blocks, which is used in pharmaceutical formulations, medical preparations with non-active ingredients, and sheet transportation, etc., can solve the problems of easy occurrence of allergies, impact on sticking performance, poor adhesion ability, etc. , to avoid skin whitish allergy, improve the mixing amount of the drug, and enhance the adhesion performance.

Active Publication Date: 2017-04-05
浙江固特新材料科技股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] The SIS medical patch used in the past has the following disadvantages: poor adhesion, low polarity, poor air permeability, prone to allergies, and the production of sweat during use will also affect its posting performance

Method used

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  • Epoxidized styrene-isoprene-styrene block copolymer medical patch and preparation method thereof
  • Epoxidized styrene-isoprene-styrene block copolymer medical patch and preparation method thereof
  • Epoxidized styrene-isoprene-styrene block copolymer medical patch and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] Example 1: Preparation of epoxidized styrene-isoprene-styrene block copolymer medical patch

[0022] raw material:

[0023]

[0024]

[0025] (1) Preparation method:

[0026] Part of naphthenic soybean oil was firstly added to the reaction kettle, ESIS and SEPS were added according to weight ratio, then antioxidant was added, heated to 160°C, stirring was started, and nitrogen was introduced to replace the gas in the kettle.

[0027] After the ESIS is completely dissolved, add the rosin pentaerythritol resin in proportion, and then add the hydrogenated rosin resin with a constant temperature.

[0028] The kettle was subjected to vacuum treatment to keep it at -0.02mPa, stirred for about 20min to lower the temperature of the kettle, and the temperature was lowered to 120°C by cooling in the reactor before discharging.

[0029] (2) Product performance parameters:

[0030] Appearance: with light yellow transparent solid glue

[0031] Non-volatile matter: 100%

...

Embodiment 2

[0039] Example 2: Preparation of epoxidized styrene-isoprene-styrene block copolymer medical patch

[0040] raw material:

[0041]

[0042]

[0043] (4) Preparation method:

[0044] Part of naphthenic soybean oil was firstly added to the reaction kettle, ESIS and SEPS were added according to weight ratio, then antioxidant was added, heated to 160°C, stirring was started, and nitrogen was introduced to replace the gas in the kettle.

[0045] After the ESIS is completely dissolved, add the rosin pentaerythritol resin in proportion, and then add the hydrogenated rosin resin with a constant temperature.

[0046] The kettle was subjected to vacuum treatment to keep it at -0.05mPa, stirred for about 20 minutes to lower the temperature of the kettle, and the temperature was lowered to 120°C by using the inner cooling of the reactor to discharge the material.

[0047] (5) Product performance parameters:

[0048] Appearance: with light yellow transparent solid glue

[0049] N...

Embodiment 3

[0057] Example 3: Preparation of epoxidized styrene-isoprene-styrene block copolymer medical patch

[0058] raw material:

[0059]

[0060]

[0061] (7) Preparation method:

[0062] Part of naphthenic soybean oil was firstly added to the reaction kettle, ESIS and SEPS were added according to weight ratio, then antioxidant was added, heated to 160°C, stirring was started, and nitrogen was introduced to replace the gas in the kettle.

[0063] After the ESIS is completely dissolved, add the rosin pentaerythritol resin in proportion, and then add the hydrogenated rosin resin with a constant temperature.

[0064] The kettle was subjected to vacuum treatment to keep it at -0.03mPa, stirred for about 20 minutes to lower the temperature of the kettle, and the temperature was lowered to 120°C by cooling in the reactor before discharging.

[0065] (8) Product performance parameters:

[0066] Appearance: with light yellow transparent solid glue

[0067] Non-volatile matter: 100...

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Abstract

The invention discloses an epoxystyrene-isoprene-styrene segmented copolymer (SIS) medicine paster and a preparation method thereof, and aims to provide the epoxystyrene-isoprene-styrene segmented copolymer (SIS) medicine paster with good adhesion ability, good air permeability and high stability and the preparation method thereof; the epoxystyrene-isoprene-styrene segmented copolymer (SIS) medicine paster includes 20-35 parts of epoxystyrene-isoprene-styrene segmented copolymer (ESIS), 10-18 parts of hydrogenatedstyrene-isoprene-styrene segmented copolymer(SEPS), 15-25 parts of epoxy soybean oil, 8-15 parts of hydroxy terminated liquid polybutadiene, 15-25 parts of hydrogenated rosin resin, 10-20 parts of rosin pentaerythritol ester and 0.2 part of an antioxidant, and the epoxystyrene-isoprene-styrene segmented copolymer (SIS) medicine paster has the advantages of strong adhesion, good air permeability, good flexibility, more stable performance, and the like.

Description

technical field [0001] The invention relates to a medical patch and a preparation method thereof, in particular to an epoxidized styrene-isoprene-styrene block copolymer (SIS) medical patch and a preparation method thereof. Background technique [0002] The SIS medical patch used in the past has the following disadvantages: poor adhesion, low polarity, poor air permeability and easy to cause allergies, and the generation of sweat during use will also affect its sticking performance. SUMMARY OF THE INVENTION [0003] The object of the present invention is to provide a kind of epoxidized styrene-isoprene-styrene block copolymer medical patch with good adhesion ability, good air permeability and high stability in order to solve the deficiencies of the above-mentioned technologies and the same Preparation. [0004] In order to achieve the above purpose, an epoxidized styrene-isoprene-styrene block copolymer medical patch designed by the present invention comprises an epoxy st...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/70A61K47/32A61K47/08A61K47/14
Inventor 邵宝有陈慧李光鹏陈惠娟
Owner 浙江固特新材料科技股份有限公司
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