External Chinese medicinal preparation for treating diabetic foot ulcer, preparation method and application thereof

A technology of diabetic foot ulcers and traditional Chinese medicine preparations, which is applied in the field of drugs for the treatment of diabetes, can solve the problems of long-term efficacy to be observed, no strict clinical research evidence for the effect of integrated traditional Chinese and Western medicine, and high mortality, so as to promote tissue repair and wound healing The effect of healing, enhancing the two-way transport function, and regulating the human nervous system

Inactive Publication Date: 2017-04-05
THE FIRST AFFILIATED HOSPITAL OF THIRD MILITARY MEDICAL UNIVERSITY OF PLA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] (4) Surgical operations and interventional therapy: Arterial stents, balloon dilatation, arterial plaque ablation, arterial plaque atherectomy, artificial vascular bypass, etc. require sophisticated and expensive equipment, heavy trauma, high risk, high cost, and many complications , high mortality, poor patient compliance
[0007] (5) Stem cell therapy: The required equipment is sophisticated and expensive, and due to ethical restrictions, most hospitals cannot carry out it, and the long-term efficacy remains to be seen
However, the evidence-based evidence for the efficacy of these therapies is insufficient and has not been recognized by the international and domestic Western medical circles
The reasons are as follows: (1) The quality of clinical research on the treatment of diabetic foot ulcers with traditional Chinese medicine is not high, and the repeatability of its curative effect is poor, so the credibility has been questioned; In one aspect, the advantages compared with Western medicine are not clear; (3) There is no strict clinical research evidence for the effect of integrated Chinese and Western medicine
[0015] Although the existing traditional Chinese medicines for external application on diabetic feet have a certain curative effect, they are slow in onset, long in duration of treatment, and poor in safety and curative effect.

Method used

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Examples

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Effect test

preparation example Construction

[0037] The preparation method of the external Chinese medicine preparation for the treatment of diabetic foot ulcer of the present embodiment comprises the following steps:

[0038] Add astragalus, scorpion, red peony, Chuanxiong, raw puhuang, Phellodendron, Coptidis, rhubarb, angelica, madder, salvia, Anemarrhena, and borneol in sesame oil according to the set weight, then decoct until slightly bitter, and then Add absolute oil, white vinegar and beeswax and stir until melted and dissolved, then cool, and finally add finely ground gypsum, stir evenly, and cool to form a paste.

[0039] In this embodiment, astragalus, scorpion, red peony root, chuanxiong, raw puhuang, cortex cortex, rhubarb rhubarb, rhubarb, angelica, madder, salvia miltiorrhiza, Anemarrhena anemarrhena, and borneol are added to the sesame oil and soaked for 3-8 days according to the set weight portion.

[0040] In the present embodiment, soak in sesame oil for 6 days.

[0041] In this example, the applicatio...

Embodiment 1

[0044] The external Chinese medicine preparation for the treatment of diabetic foot ulcer of the present embodiment, the raw material of Chinese medicine preparation comprises the following components by weight: 12 parts of Radix Astragali, 4 parts of Scorpion, 4 parts of Radix Paeoniae Rubra, 6 parts of Rhizoma Chuanxiong, 6 parts of Raw Puhuang, Phellodendron Phellodendri 6 parts, 6 parts of coptis, 3 parts of rhubarb, 4 parts of angelica, 4 parts of madder, 6 parts of salvia miltiorrhiza, 31 parts of gypsum, 6 parts of anemarrhena, and 0.6 part of borneol.

[0045] Add astragalus, scorpion, red peony root, Chuanxiong, raw puhuang, Phellodendron cortex, Coptis rhizome, rhubarb, angelica, madder, salvia miltiorrhiza, Anemarrhena anemarrhena, and borneol in sesame oil for 6 days, then decoct until slightly bitter, then add the absolute oil and Stir the white vinegar and beeswax until they melt and dissolve, then cool, then add finely ground gypsum, stir evenly, and cool to form...

Embodiment 2

[0047] The external Chinese medicine preparation for the treatment of diabetic foot ulcer in this embodiment, the raw materials of the Chinese medicine preparation include the following components by weight: 6 parts of Astragalus, 1 part of Scorpion, 1 part of Radix Paeoniae Rubra, 3 parts of Rhizoma Chuanxiong, 3 parts of Raw Puhuang, Phellodendron Phellodendri 3 parts, 3 parts of coptis, 1 part of rhubarb, 1 part of angelica, 1 part of madder, 3 parts of salvia miltiorrhiza, 25 parts of gypsum, 3 parts of anemarrhena, 0.1 part of borneol.

[0048] Add astragalus, scorpion, red peony root, Chuanxiong, raw puhuang, cortex cortex, coptis, rhubarb, angelica, madder, salvia miltiorrhiza, Anemarrhena anemarrhena, and borneol into sesame oil, soak for 3 days, decoct until slightly bitter, then add absolute oil and Stir the white vinegar and beeswax until they melt and dissolve, then cool, then add finely ground gypsum, stir evenly, and cool to form a paste.

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PUM

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Abstract

A traditional Chinese medicine preparation for external use and for treating diabetic foot ulcer, and a preparing method thereof are disclosed. The traditional Chinese medicine preparation comprises following raw materials by weight: radix astragali, scorpion, red paeony root, ligusticum wallichii, crude pollen typhae, amoorcorn tree bark, Chinese goldthread, rheum officinale, Chinese angelica, madder, red sage root, gypsum, rhizoma anemarrhenae and borneol. Effective constituents of the components are synergistic, and play roles of promoting blood circulation to remove blood stasis, diminishing swelling, promote tissue regeneration, clearing heat and toxicity and discharging pus, thus resolving stagnation, dredging collaterals, allowing normal circulation of qi and blood in acra, making muscle nutrition sufficient, eliminating sore, gaining flesh, and effectively curing foot ulcer caused by diabetes.

Description

technical field [0001] The invention relates to a medicine for treating diabetes, in particular to an external Chinese medicinal preparation for treating diabetic foot ulcer, a preparation method and application thereof. Background technique [0002] Diabetic foot is a common complication of diabetes, which seriously affects the labor ability and quality of life of patients. Diabetic foot ulcer is the main clinical manifestation of diabetic foot, and its amputation rate is 15-20 times that of non-diabetic patients. Studies have shown that the amputation-related all-cause mortality of diabetic patients is more than 5 times higher than that of non-diabetic patients. There are about 92 million diabetic patients in my country, and the incidence of diabetic foot is about 0.9%-14.5%. Diabetic foot has brought a heavy burden to social medical resources. In Western countries, the cost of diabetic foot ulcers is $16,000-27,000 per patient, and the medical cost of amputation is as h...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/8964A61K9/06A61P17/02A61P3/10A61K33/06A61K35/646A61K31/045
Inventor 陈兵李树法张玲周海舟陈军
Owner THE FIRST AFFILIATED HOSPITAL OF THIRD MILITARY MEDICAL UNIVERSITY OF PLA
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