112 results about "Arnebia euchroma" patented technology

The invention relates to a method for producing alkannin by utilizing Arnebia euchroma(Royle)Johnst hairy root. The method includes selection and processing of Arnebia euchroma(Royle)Johnst explant, activation culture of agrobacterium rhizogene, infection of cotyledon explant and induction of hairy root, obtaining of sterile Arnebia euchroma(Royle)Johnst hairy root system and liquid culture of Arnebia euchroma(Royle)Johnst hairy root as well as alkannin production. The used hairy root has the characteristic of rapid and autonomous growth on culture medium without exogenous hormones, thus the method not only can overcome the defects that cell culture grows slowly and hormone is required to be additionally added to maintain the growth thereof when utilizing cell culture to produce alkannin, and the method has the advantages of stable alkannin throughput, simple operation in cultivation, lower cost and no restriction of climate and land natural conditions. Especially the invention provides a stable and continuable novel medicine source for producing alkannin by utilizing hairy root culture method and provides reliable source and material basis for alkannin mass production by applying bioreactor in the future.

The present invention belongs to the technical field of medicine, and relates to a high-speed countercurrent chromatography continuous circulation method for separating and preparing naphthoquinone compounds from Arnebia euchroma (Royle) Johnst. According to the method, the natural naphthoquinone compounds represented by a formula (I) are separated and prepared by using a high-speed countercurrent chromatography continuous circulation separation method, n-hexane, ethyl acetate, acetonitrile and water are used as a two-phase solvent system for high-speed countercurrent chromatography separation, an online storage technology and a circulation elution mode are combined, the fractions containing the target compound are subjected to continuous circulation elution, and the fractions are collected to obtain shikonin with a purity of more than 95%, propionylshikonin with a purity of more than 95%, deoxyshikonin with a purity of more than 95%, (beta,beta-dimethylacryl)shikonin with a purity of more than 95% and isovalerylshikonin with a purity of more than 95%. With the method of the present invention, the high purity naphthoquinone compounds can be obtained through the one separation purification, such that the method has advantages of simple operation, rapidness and high efficiency, and is suitable for the separation and preparation of naphthoquinone and a variety of natural compounds. The formula (I) is defined in the specification.

The invention discloses a method for separating naphthoquinone active ingredients from sinkiang arnebia root, which comprises the following steps of: A, baking dried stems of the sinkiang arnebia root, performing ultrasonic extraction by using ethanol, and performing ultrasound so as to obtain dry extract; B, extracting ethanol dry extract by using solvents such as petroleum ether and ethyl acetate to prepare extract obtained by using ether and ethyl acetate; C, ultrasonically dissolving the extract by using the ethyl acetate that has equal volume to that of the extract, evaporating to dryness until the smell of ethyl acetate does not exist, connecting serially connected columns onto a middle-low pressure preparation type chromatographic column; D, eluting the columns under a screen monitoring figure of the middle-low pressure preparation type chromatographic column by using the petroleum ether as an eluant,, and collecting flowing fractions so as to obtain compounds; E, changing two serially connected columns on a middle-low pressure preparation type chromatography into a C18 column, dissolving the compounds with methanol, and processing the dissolved compounds by using the C18 column so as to purify the compounds; and F, subjecting the compounds to an alkaline reaction to obtain a purple colour and subjecting the compounds to a leukomethylene colour test to obtain a positiveresult. The method is easy to operate and the operation is easy and simple. The middle-low pressure preparation chromatography is used in the method; the method is an optimum technology for separating anticancer active ingredients efficiently; furthermore, the content of the separated naphthoquinone active ingredients is greater than 95 %.

The invention relates to an identification technology of Arnebia Euchroma and Radix Lithospermi, and concretely relates to a method for accurately identifying medicinal materials and extracts (comprising Radix Arnrbiae-containing compound traditional Chinese medicines, and naphthoquinone component monomers) of Arnebia Euchroma and Radix Lithospermi by establishing LC-CD through utilizing the inverse relationship of canini enantiomers contained in Arnebia Euchroma and Radix Lithospermi respectively in the LC-CD. The medicinal materials and extracts (comprising Radix Arnrbiae-containing compound traditional Chinese medicines, and naphthoquinone component monomers) of Arnebia Euchroma and Radix Lithospermi can be accurately identified and distinguished through the method.

The invention relates to a skin topical composition with the efficacy of promoting wound healing and/or scar repair. The skin topical composition includes (A) concentrated birch sap, and (B) one or more of Sanguisorba root extract, Coptis root extract, Arnebia extract, allantoin, Salvia miltiorrhiza extract, astragalus extract, pearl powder and asiaticoside, wherein the concentrated birch sap hasa concentration multiple of about 1.2-6 times, preferably about 1.5-5 times, more preferably about 1.5-3 times.

The invention relates to fructus trichosanthis root tea capable of relieving chest stuffiness and reducing mass and a production method thereof. The fructus trichosanthis root tea capable of relieving chest stuffiness and reducing mass is prepared from fructus trichosanthis root, eagle wood, arnebia euchroma, Rhus chinensis, costus root, myrobalan fruit, cress, perilla fruit, mistletoe, piper longum and common bombax flower, which serve as raw materials. The production method mainly comprises the following steps: (1) getting the materials ready according to a formula, and cleaning; (2) baking and sterilizing; (3) selecting the baked raw materials according to the formula; (4) grinding the raw materials, mixing the raw materials and frying the raw materials in a mixed manner; (5) soaking the raw materials, decocting time after time, and extracting filtrates time after time; (6) mixing the filtrates, concentrating the filtrates, so as to obtain a concentrate, and drying the concentrate, so as to obtain mixed powder; (7) bagging and disinfecting, thereby preparing a finished product. The fructus trichosanthis root tea capable of relieving chest stuffiness and reducing mass, disclosed by the invention, has the effects of relieving chest stuffiness and reducing mass, invigorating Qi and soothing nerve as well as clearing heart-fire and easing mind in long-term use.

The invention discloses a handmade soap containing a natural herb-radix lithospermi and a preparation method of the handmade soap. The handmade soap is prepared from radix lithospermi soaking oil, coconut oil, palm kernel oil, canola oil, sweet almond oil, rice bran oil, grape seed oil, camellia oil, analytically-pure caustic soda and purified water according to a certain proportion. The handmade radix lithospermi soap is prepared at room temperature in the whole process, natural ingredients of the vegetable oil are preserved to the maximum limit, and glycerin generated in the saponification process is retained; no antibacterial agent or preservative is added in the handmade soap, and the handmade soap does not contain chemical pigment or artificial essence and is mild and non-irritating to the skin; the handmade soap can be used for cleansing the face and a body, can remove skin dirt deep, has the functions of diminishing inflammations, removing acnes, achieving calming and repairing the skin, can effectively solve the skin eczema problem and is a cleansing product which can be used for a long term and used for cleansing and caring the skin.

The invention discloses a medicinal preparation for treating chronic cervicitis. The medicinal preparation comprises the following raw medicinal materials: 20-30g of honeysuckle, 20-30g of salvia miltiorrhiza, 20-30g of arnebia euchroma, 15-25g of cistanche, 15-25g of scutellaria baicalensis, 15-25g of scutellaria baicalensis, 15-25g of radix polygonati officinalis, 10-20g of lycopodium clavatum, 10-20g of raw liquorice, 10-20g of dodder, 5-15g of dried tangerine peel, 5-15g of polygonum viviparum, 5-10g of oldenlandia diffusa, and 5-10g of Chinese yam. A preparation method of the medicinal preparation comprises the following steps: mixing the raw medicinal materials, decocting, and filtering to obtain filtrate; adding water into decoction dregs, decocting, and filtering to obtain filtrate; combining the two filtrates, conventionally concentrating in reduced pressure and drying to obtain fine powder; and preparing tablets or capsules. When the medicinal preparation is used in treatment, the medicinal preparation is taken orally twice a day, in the morning and evening, and about 5g each time. Years of clinical application proves that the total effective rate of the medicinal preparation is over 90 percent, the curative effect is good, and the medicinal preparation does not have toxic or side effect.

The invention discloses a preparation method of a botanical mice composite sterilant Nongda-1, which belongs to the technical field of medicine compound. By researching reasonable ratio and synergism of the medicinal materials, the medicines prepared by the pharmaceutical composition of the invention have good effect for controlling mice fertility, alkannin extracted from roots of Macrotomia euchroma is combined with quinsetrol, an unique technology is employed, so that the botanical mice composite sterilant can be prepared, and the botanical mice composite sterilant has good effect for controlling mice fertility.

The invention discloses a preservative-free natural plant hand sanitizer and a preparation method thereof. The preservative-free natural plant hand sanitizer is mainly prepared from the components: apoplar flower extractive, arnebia euchroma soak oil, tourmaline powder and plant amino acid, wherein preparation of the poplar flower extractive comprises the steps: poplar flowers are smashed and added with an ethanol aqueous solution according to the material to liquid weight ratio of 1:(5 to 20) to be evenly stirred, ultrasonic extraction is conducted for 1-3 h at the temperature of 80-100 DEGC, filtering and concentrating are conducted, 95% ethanol with the volume being 3-5 times that of the mixture is added, the mixture is placed into a refrigerator at 4 DEG C for 24-48 h, refrigerated centrifugation is conducted, and the poplar flower extractive is obtained. The preservative-free natural plant hand sanitizer achieves the purposes of sterilizing, bacterium inhibition and corrosion prevention through the natural plant poplar flower extractive, an arnebia euchroma extractive and the like, and does not contain chemical substance preservatives, the risks such as sensitization, internal secretion interfering and even carcinogenesis which are caused by the chemical preservatives are avoided, degradation is easy, no residue exists, and no harm is caused to body health and the waterenvironment; and the poplar flower extractive is used for preparing the hand sanitizer for the first time, waste utilization is achieved, and the economic benefits are effectively increased.

The invention discloses a scalding liquid, which comprises the following components in parts by weight: 10-18 parts of golden cypress, 10-18 parts of scutellaria baicalensis, 10-18 parts of rheum officinale, 3-8 parts of garden burnet, 3-7 parts of gallnut, 3-8 parts of polygonum cuspidatum, 3-6 parts of sophora flavescens, 3-8 parts of carbonized hair, 3-8 parts of arnebia euchroma and 4-8 parts of borneol, wherein every 100 g of the total weight of the medicines is added with 500 ml 95% ethanol. The preparation method of the scalding liquid is as follows: except for the carbonized hair and the borneol, the remainder medicines are cleaned and aired; every 100 g of the total weight of the medicines is added with 500 ml distilled water, and is dipped for one day; then 500 ml 95% ethanol is added; the borneol is not dissolved in water, can be directly added in ethanol for dissolving and dipping for 10 days, and is packaged in small bottles. The scalding liquid of the invention has the advantages of convenience in use, pain relief after use, no fester, short treatment time, no toxic or side effects, simple preparation technique, convenience in treatment and use and low cost.

The invention discloses application of radix arnebiae seu lithospermi naphthoquinone compounds to preparation of medicaments for treating Crohn's disease. The invention further discloses medical application of one or more radix arnebiae seu lithospermi extracts with a formula shown in the specification.

The invention relates to the technical field of plant extraction and in particular relates to radix lithospermi extract as well as a preparation method and application thereof. The preparation methodof the radix lithospermi extract, disclosed by the invention, comprises the following steps of step 1, crushing a radix lithospermi medicinal material to obtain radix lithospermi medicinal material powder; step 2: carrying out micro-jet extraction on the radix lithospermi medicinal material powder to obtain radix lithospermi extract, wherein a solvent in the micro-jet extraction is matrix oil forcosmetics and/or edible oil. In the preparation method, a non-organic solvent matrix oil for the cosmetics and/or the edible oil are/is used, so that residues of an organic solvent in the radix lithospermi extract are avoided and the utilization safety of the radix lithospermi extract is ensured. Furthermore, the radix lithospermi extract prepared by the preparation method is oil-soluble radix lithospermi extract; the preparation method has the advantages that the extraction rate of p-hydroxylnaphthoquinone total pigments is high, the damage to effective components of radix lithospermi is lessand the effect of the radix lithospermi is easy to express sufficiently; meanwhile, the original color and luster of the radix lithospermi are also protected.

The invention provides a hydroquinone compound which has anti-HCV (Hepatitis C Virus) activity, a benzo-geijerene framework and the selection index of 6.32 and can be used as a lead compound for treating HCV. The hydroquinone compound is extracted and separated from stem barks of Arnebiaeuchroma; and the hydroquinone compound has the advantages of simple and easiness of extraction and separation methods, low cost, high efficiency and yield and good extract quality. A molecular formula of the hydroquinone compound with the anti-HCV activity is C16H18O3, and a chemical structure is shown as a specification.

The invention discloses an external medicinal liquid for treating scald, which is prepared from the following components by weight: 8-12g of peach tree skin, 8-12g of phellodendron, 8-12g of coptis root, 8-12g of radix arnebiae seu lithospermi, 8-12g of garden burnet root, 8-12g of willow skin, 8-12g of glossy privet leaf, 4-6g of pseudo-ginseng, 4-6g of cottonrose hibiscus flower, 4-6g of lumbricus, 4-6g of amur grape root and 950-1050g of white wine. The external medicinal liquid has the functions of removing heat to cool blood, invigorating the circulation of blood and removing stagnation, diminishing inflammation and relieving pain, and stopping bleeding and promoting tissue regeneration. A patient suffering from scald can be cured completely without scars.

The invention discloses an infant soothing cream and a preparation method thereof. The infant soothing cream is prepared from the following components in percentage by mass: 10-30% of a thickening stabilizer, 0.06%-0.55% of a skin conditioning agent; 0.1%-2% of an anti-allergy agent; 0.1%-2% of an antioxidant; the balance of an emollient; wherein the emollient is prepared from camellia seed oil, radix arnebiae seu lithospermi oil, olive fruit oil and peppermint oil. The preparation method of the infant soothing cream is simple, and the infant soothing cream is prepared by heating and uniformlymixing the components in batches and then cooling and freezing the mixture. The infant soothing cream disclosed by the invention has various effects of resisting inflammation, repairing, relieving itching, calming and the like, is safe and non-irritant, and can effectively prevent and treat skin problems such as eczema, saliva eruption, red envelope biting by mosquitoes, bruising and the like ofinfants.

The invention discloses acne removal cold process soap and a preparation method thereof. The acne removal cold process soap is prepared proportionally from camellia oil and extracted Arnebia euchroma oil, camellia oil, semen armeniacse dalce oil, grape seed oil, rice bran oil, coconut oil, sodium hydroxide, purified water, Ruyijinhuang powder, traditional Chinese medicine extract and plant essential oil. According to the formula disclosed by the invention, the effective components such as Ruyijinhuang powder, Arnebia euchromaand traditional Chinese medicine extract have good functions of sterilizing and diminishing inflammation, activating blood and resolving stasis and repairing pimple skin; and the prepared cold process soap realizes the effects of controlling oil and removing acne while cleaning the skin, and avoids the feeling of dryness and irritation.

The present invention discloses a healthy bread preservative. The preservative is prepared from the following raw materials in parts by weight: 62-64 parts of artocarpus champeden, 53-55 parts of solanum mammosum, 46-48 parts of southeast Asia red bananas, 42-44 parts of bergamots, 2-4 parts of trehalose, 1.4-1.6 parts of arnebia euchroma polysaccharides, 0.4-0.6 part of lecithin, and 0.2-0.3 part of indigo naturalis. The provided healthy bread preservative is completely extracted from the pure natural plants with antibacterial effects, has sweet and sour tastes, is free of peculiar tastes, and does not affect the sweet and fragrant tastes of the bread. The whole process is free of any toxic chemical reagents, safe and healthy, and does not use a high temperature. The preservative is simple in preparation, high in efficiency, and wide in range of sources, and saves costs by 13%. The arnebia euchroma polysaccharides are subjected to a pure natural extraction, and safe and healthy, and the extraction rate is increased by 9.6%, and the cost is saved. A nutritional agent is added, plant extractants are complemented with each other, and nutrition and bactericidal functions are significantly improved.

The invention discloses a medicine for treating infantile balanitis and a preparation method of the medicine. The medicine is mainly prepared from salvia prionitis, fructus kochiae, arnebia euchroma, herba schizonepetae, garlic, agrimonia pilosa ledeb, purslane, spina gleditsiae, sophora flavescens, achyranthes bidentata and other medicines in a certain weight ratio. The medicine has the functions of clearing heat and removing toxicity, dissipating blood stasis and reducing edema, drawing out poison and clearing pus, is quick in response and good in curative effect when used for treating infantile balanitis, and does not have toxic or side effect.

The invention discloses a shikonin-containing band-aid and a preparing method thereof. The band-aid is composed of plain-cloth adhesive tape, a water absorption pad and release paper. The water absorption pad is evenly coated with a shikonin mixture, and the shikonin mixture is specially prepared in the mode that shikonin purified and separated from arnebia euchroma is embedded with gamma-cyclodextrin. The band-aid prepared with the method has the functions of a common band-aid, and also has the specific pharmacologic effect of the shikonin, and the effects of resisting bacteria, diminishing inflammation, stopping pains, promoting wound healing, reducing scar forming and the like are enhanced; the preparing method is easy to operate, free of human-body irritation and human-body obvious toxicity and capable of being widely applied to small wound treatment.

The invention belongs to the technical field of medicines and in particular relates to a Tibetan medicine for diabetes as well as a preparation method and application of the Tibetan medicine. The Tibetan medicine for diabetes disclosed by the invention comprises the following Tibetan medicines in parts by weight: 3.0-5.0 parts of rhizoma curcumae longae, 3.0-5.0 parts of turnip, 1.0-2.0 parts of radix onosmatis, 0.3-0.7 part of rhizoma acori graminei, 0.8-1.6 parts of phyllanthus emblica, 0.10-0.30 part of safflower and 0.6-1.0 part of dry honey paste. The Tibetan medicine for diabetes disclosed by the invention is capable of lowering fasting blood-glucose and postprandial blood sugar of patients and enhancing the human ability of regulating the blood sugar, can avoid reoccurrence of the diabetes after drug withdrawal, and has ideal long-term follow-up results.

The invention relates to an anti-inflammatory tincture and a preparing method thereof and belongs to the technical field of Chinese medicine. The anti-inflammatory tincture comprises the following ingredients in a part by weight: 22-26 parts of rhizoma paridis, 32-34 parts of rhubarb, 4-5 parts of safflower, 7-10 parts of radix angelicae dahuricae, 15-18 parts of giant knotweed rhizome, 7-9 parts of arnebia euchroma, 7-9 parts of radix aconiti agrestis, 11-14 parts of psammosilene tunicoides, 2-3 parts of semen strychni, 16-18 parts of arisaema aridum, 16-18 parts of radix sophorae flavescentis, 15-18 parts of salvia miltiorrhiza and 4-7 parts of short-pedicel aconite root. The preparing method of the anti-inflammatory tincture is simple. The prepared anti-inflammatory tincture has great effects of clearing internal heat, dispelling humidity, purging pathogenic fire, relieving toxins, promoting blood circulation, dissolving stasis, reducing swellings, alleviating pain, relieving inflammations and discharging pus.