Botanical mice composite sterilant preparation method

A sterile agent, rodent technology, applied in the fields of botanical equipment and methods, plant growth regulators, animal repellents, etc., can solve problems such as unsatisfactory, and achieve good results

Pending Publication Date: 2017-05-17
INNER MONGOLIA AGRICULTURAL UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

In China, tripterygium wilfordii, gossypol, rue, camellia saponin, castor oil, trichosanthin, colchicine, castor oil, curcumol, neem...

Method used

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  • Botanical mice composite sterilant preparation method
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  • Botanical mice composite sterilant preparation method

Examples

Experimental program
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Effect test

application ， example 1

[0039] Practical application, example 1, the effect of shikonin on the reproduction of mice

[0040] In order to clarify the anti-fertility effect of the plant extract shikonin, Kunming mice were used as the experimental objects, firstly divided into 4 groups, 15 pairs in each group, of which 1 group was the control group, and the remaining 3 groups were treated with 5mg / kg and 20mg / kg respectively. and 50mg / kg concentration of shikonin for intragastric administration. Dissect and measure 3 organ coefficients including female uterus, male seminal vesicles and testis and 4 indicators of sperm density. Secondly, one ideal concentration of shikonin was selected for breeding experiments, and the newly selected mice were divided into 4 groups, 15 pairs in each group, 1 group for the control group, and 3 different treatments for the remaining 3 groups, male treatment group and female treatment group And the male and female treatment group, the treatment group was given the breeding...

application ， example 2

[0059] Practical application, example 2, the influence of sterile agent of the present invention on the reproduction of meridian gerbils

[0060] Meriones meridianus were divided into 3 groups, including control group, female treatment group and male treatment group, and the effect of sterility agent was studied experimentally. The results showed that during the first breeding of Meridian gerbils in the annual breeding period, the average litter size of the male treatment group was significantly reduced (F=12.76, P<0.01), which was 1.42±0.12, and the anti-fertility rate reached 42.86%. , the average litter size of the female treatment group and the male treatment group were significantly reduced (F=11.71, P<0.01), respectively 1.42±0.13 and 0.14±0.04, and the anti-fertility rates reached 57.14% and 85.78% respectively; 2-3 times, 0-2 times in the two treatment groups, both were significantly lower than the control group (F=11.87, P<0.01); the reproductive start period of the t...

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Abstract

The invention discloses a preparation method of a botanical mice composite sterilant Nongda-1, which belongs to the technical field of medicine compound. By researching reasonable ratio and synergism of the medicinal materials, the medicines prepared by the pharmaceutical composition of the invention have good effect for controlling mice fertility, alkannin extracted from roots of Macrotomia euchroma is combined with quinsetrol, an unique technology is employed, so that the botanical mice composite sterilant can be prepared, and the botanical mice composite sterilant has good effect for controlling mice fertility.

Description

technical field [0001] The invention relates to a rodent sterility agent and a preparation method thereof, in particular to a preparation method of a rodent sterility agent Nongda-1, which belongs to the technical field of pharmaceutical compound. Background technique [0002] Sterility control is one of the emerging new technologies for controlling pests in the world. Its principle is to control the population of rodents by reducing the reproduction of rodents. Through the model, it is found that in a population of 10,000 rodents, if 70% of the individuals are killed for 3 consecutive generations, the population can still return to the original level after 26 generations; but if 70% of the individuals are killed for 3 consecutive generations After 19 generations, the population can become extinct. Therefore, the use of sterility control is more effective than traditional rodent control. Sterility control also has the characteristics of safe operation and less pollution to...

Claims

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Application Information

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IPC IPC(8): A01N45/00A01N35/06A01P23/00
CPCA01N45/00A01N25/004A01N35/06A01N2300/00
Inventor 付和平包达尔罕满都呼袁帅杨素文武晓东
Owner INNER MONGOLIA AGRICULTURAL UNIVERSITY
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