24 results about "GYNECOLOGIC DISORDERS" patented technology

The utility model provides a pair of full-hemp surface layer menstrual period trousers, which comprises a full-hemp surface layer menstrual period trousers body which is in the shape of underpants formed by cutting and compounding non-woven fabrics and rubber bands. The full-China-hemp surface layer menstrual period pants body sequentially comprises a surface layer, a flow guide layer, an absorber, an anti-leakage bottom film and an elastic surrounding body from the skin contact surface to the bottom, and the surface layer is made of full-China-hemp non-woven fabric. The surface layer is the non-woven fabric made of all China-hemp fibers, the China-hemp fibers belong to natural plant fibers and can destroy the thallus structure of bacteria and prevent anaerobic bacteria from surviving, the China-hemp fibers have moisture absorption and quick drying functions, a dry environment is not beneficial to bacterial reproduction, menstrual blood is quickly pulled to the bottom through the multi-layer tiled structure in the absorber, and therefore the menstrual blood can be quickly absorbed. The China hemp fibers can effectively inhibit bacterium breeding and prevent bacteria from breeding upwards, skin or gynecological diseases caused by contact with skin are avoided, and the use requirement of women for menstrual period trousers is met.

This invention discloses a porous carbon-based dual-drug-loaded nanomaterial for sustained release. The material uses a thermosensitive polymer as a matrix and cellulose nanocrystals modified with cationic surfactants as a reinforcing phase, loading both hydrophilic and hydrophobic drugs. This material can be used to prepare therapeutic drugs for gynecological diseases and infertility, as well as drug delivery devices. Furthermore, this invention provides a uterine scaffold prepared using this material, which can be fabricated using 3D printing technology. Utilizing the PNIPAm hydrogel network and its temperature-responsive properties, hydrophilic drugs can be loaded at low temperatures. The high mechanical strength of CNC machining allows for the loading of hydrophobic drugs while improving the mechanical properties of the hydrogel matrix, thus solving the problems of easy detachment and bleeding in existing technologies.

The invention belongs to the technical field of antibacterial products, and particularly relates to a female private part antibacterial composition. Through the synergistic effect of the white willow bark extract, the melaleuca alternifolia leaf oil, the sandalwood essential oil and the cedar wood oil, the prepared antibacterial composition has an excellent antibacterial effect, is mild and non-irritant, and can solve the problems that an existing female private part antibacterial agent is limited in antibacterial effect, and the antibacterial effect is poor; and gynecological diseases can be aggravated after long-term use. Wherein the white willow bark extract is prepared through enzymolysis of a compound enzyme composed of cellulase, feruloyl esterase and alkaline protease, the enzymolysis efficiency can be improved, and then the release rate of active ingredients in white willow bark is increased. The preparation method of the antibacterial composition is simple and convenient in operation process and suitable for industrial production. The antibacterial composition is applied to preparation of female private part care products and has good application value.

The invention relates to the technical field of modernization of traditional Chinese medicines, in particular to a nano-vesicle, a preparation method and application of the nano-vesicle in preparation of an endometrial injury repairing medicine. The preparation method comprises the following steps: taking a periplaneta americana ethanol extracting solution, and adding a buffer solution to prepare diluted homogenate; performing differential centrifugal treatment on the homogenate; filtering the supernatant obtained by the differential centrifugation treatment, and then centrifuging for 60-120 minutes by 100000g of the supernatant to obtain a precipitate; and re-suspending the precipitate to obtain the periplaneta americana ethanol extract source nano-vesicles. The periplaneta americana ethanol extract is used as a starting material to enrich the nano-vesicles for the first time, the combined process of differential centrifugation, membrane filtration and ultracentrifugation is adopted, the obtained nano-vesicles can be applied to the field of endometrial injury repair, especially treatment of gynecological diseases such as intrauterine adhesion and infertility with thin intima, and the blank in the technical field is filled.

The application discloses a cassia twig composition and a preparation method and application thereof in preparing medicines for treating gynecological diseases, and relates to the technical field of medicines.The preparation method comprises the following steps: (1) after mixing cassia twig and licorice, alcohol ultrasonic treatment is conducted to obtain alcohol extraction liquid and dregs; (2) after mixing the dregs, white peony root, Chinese date and fresh ginger, water extraction is conducted to obtain water extraction liquid; (3) the alcohol extraction liquid is concentrated and treated by macroporous resin to obtain eluent; and (4) the eluent and the water extraction liquid are combined, concentrated and dried to obtain the cassia twig composition.The macroporous resin treatment is as follows: the volume of the sample liquid is 5BV-10BV, the sample liquid is loaded at a flow rate of 2BV / h-8BV / h, 3BV-7BV of 70%-80% ethanol is used for elution at a flow rate of 1BV / h-5BV / h.The prepared cassia twig composition can better treat cold coagulation and blood stasis dysmenorrhea, and more choices are provided for the treatment of primary dysmenorrhea and other gynecological diseases.

The invention discloses temperature-sensitive hydroxybutyl polyvinyl alcohol, sustained-release hydrogel and a preparation method and application thereof, and belongs to the field of pharmaceutical preparations. Temperature-sensitive hydroxybutyl polyvinyl alcohol is synthesized by grafting modified polyvinyl alcohol in an alkaline aqueous solution through epoxybutane, no organic solvent is used in the preparation process, and the preparation method is simple, economical and convenient. When the grafting substitution degree of the hydroxybutyl polyvinyl alcohol is 20%-60%, the hydroxybutyl polyvinyl alcohol is dissolved in deionized water or normal saline at a low temperature, progesterone microcrystals are added and uniformly stirred to obtain a drug-loaded gel precursor dispersion liquid, gel transformation is performed in a use environment at a gel transformation temperature or above, and the progesterone vaginal sustained-release hydrogel is formed. The gel is soluble in water at a low temperature, has good fluidity, can be conveniently filled into tissues, and forms gel at a body temperature, and has good tissue mucosa retention. As a progesterone vaginal sustained-release carrier material, the hydrogel disclosed by the invention is expected to be applied to development of products for preventing or treating gynecological diseases or assisting fertility.

The invention discloses a Chinese eaglewood traditional Chinese medicine composition for treating male prostatic diseases and gynecological diseases through eating and roasting and a preparation method. The traditional Chinese medicine composition is characterized by being prepared from the following raw materials in parts by weight: 10-30 parts of agilawood, 10-25 parts of angelica sinensis, 8-20 parts of ligusticum wallichii, 15-30 parts of radix paeoniae alba, 20-40 parts of prepared rehmannia root, 15-35 parts of astragalus membranaceus, 10-30 parts of codonopsis pilosula, 10-25 parts of rhizoma atractylodis macrocephalae, 10-25 parts of poria cocos, 5-15 parts of liquorice, 10-25 parts of herba epimedii, 10-25 parts of morinda officinalis, 10-25 parts of cistanche, 10-30 parts of leonurus and 8-20 parts of rhizoma cyperi. The preparation method comprises the following steps: raw material pretreatment, crushing, mixing, strip making, drying, and roasting and eating dual-purpose treatment. Through a unique formula and a preparation technology, the traditional Chinese medicine composition has the characteristics of eating and roasting, effectively treats male prostatic diseases and gynecological diseases, and overcomes the defects of the existing treatment means at the same time.

This invention relates to a pharmaceutical composition for treating gynecological diseases, its preparation method, and its application, belonging to the field of gynecological disease treatment technology. The pharmaceutical composition comprises the following raw materials: *Sedum aizoon*, *Trichosanthes kirilowii* seeds, and *Xanthoceras sorbifolium* leaves; the weight ratio of *Sedum aizoon*, *Trichosanthes kirilowii* seeds, and *Xanthoceras sorbifolium* leaves is (10-20):(6-9):(3-7). This invention mainly utilizes a suitable ratio of *Sedum aizoon*, *Trichosanthes kirilowii* seeds, and *Xanthoceras sorbifolium* leaves for synergistic effect, significantly improving the therapeutic efficacy of the pharmaceutical composition for gynecological diseases such as polycystic ovary syndrome, providing a new approach for treating gynecological diseases, and has broad clinical application prospects.

The invention relates to the field of traditional Chinese medicine formulas, in particular to a formula for treating gynecological diseases and a preparation method thereof. The invention discloses a formula for treating gynecological diseases and a preparation method thereof. The traditional Chinese medicine composition is prepared by mixing the following raw materials in parts by weight: 58-89 parts of radix et rhizoma rhododendri chinensis, 36-59 parts of ox tail knot, 22-46 parts of sclerotium rolfsii, 24-35 parts of cooked rice, 43-55 parts of pig hands, 32-40 parts of pig feet, 28-40 parts of pigtails, 30-47 parts of glutinous rice sweet wine, 25-30 parts of motherwort, 45-72 parts of herba tarragon, 14-35 parts of radix sophorae flavescentis slices, 4-20 parts of edible oil, 1-10 parts of edible salt and 3-15 parts of native eggs. The traditional Chinese medicine has the beneficial effects of effectively treating inflammation in gynecological diseases, promoting blood circulation to remove blood stasis, and treating traumatic injuries by oral administration.

To provide a prophylactic and / or therapeutic agent for iron-deficiency anemia in a hypermenorrhea patient and / or a patient suffering from a hypermenorrhea-associated gynecologic disease.SOLUTION: According to the present invention, a prophylactic and / or therapeutic agent for iron-deficiency anemia in a hypermenorrhea patient and / or a patient suffering from a hypermenorrhea-associated gynecologic disease can be provided, which contains ferric citrate as an active ingredient.SELECTED DRAWING: None

The artificial insemination transplantation tool comprises a propelling assembly and a protection assembly which are arranged on a pipetting cylinder, the propelling assembly comprises a liquid storage bottle arranged at one end of the pipetting cylinder, the front end of the liquid storage bottle is embedded into the pipetting cylinder, an infusion hose is arranged in the pipetting cylinder, and a piston baffle is arranged at the end, close to the liquid storage bottle, of the infusion hose; the piston baffle and the pipetting cylinder form a first closed cavity; the protection assembly comprises a second closed cavity formed in the end of the pipetting barrel, the second closed cavity is communicated with the first closed cavity through a ventilation pipe, the peripheral side face of the end of the pipetting barrel is sleeved with an elastic air bag, the circumferential inner side of the elastic air bag is provided with a plurality of one-way air valves, and the end of the pipetting barrel is hinged to a connecting part arc-shaped cover plate. The infusion hose is protected through the arc-shaped cover plate, the infusion hose is effectively prevented from touching the inner wall of the genital tract, the prevention effect of gynecological diseases is improved, the infusion hose is arranged in the pipetting cylinder, the infusion hose can enter the cervix uteri more easily, and the artificial insemination success rate is effectively increased.

1. The name of the design product: vaginal dilator. 2. The use of the design product: for gynecological examination when the vagina is dilated. 3. The design points of the design product: in shape. 4. The picture or photo that best shows the design points: perspective view.

1. The name of this design product: Gynecological medication dispenser. 2. Purpose of this design product: used for applying medicine for gynecological diseases. 3. The key point of the design of this product lies in its shape. 4. The picture or photo that best illustrates the design points: Stereoscopic drawing 1.

The invention provides a human body lubricant containing hyaluronic acid for vagina lubrication and a preparation method and application thereof, the human body lubricant is prepared from the following raw materials in parts by weight: 0.5-2.5 parts of sodium hyaluronate, 6-10 parts of plant extract, 0.5-0.8 part of alpha-ketoglutaric acid, 5-8 parts of 1, 2-propylene glycol, 10-15 parts of glycerol and 3-5 parts of arginine modified hydroxyethyl cellulose, 1-3 parts of a pH regulator, 0.05-0.1 part of a preservative and 60-80 parts of purified water. The human body lubricant disclosed by the invention has a good lubricating effect, is not sticky and greasy, reduces a dynamic friction coefficient, is good in moisture retention, reduces dryness of women caused by lack of secretions, improves sexual life experience, has no side effects, is high in safety and has no irritation to vaginal mucosa. The pH value is consistent with the normal pH value of the female vagina, the balance of the micro-ecological environment of the female vagina is maintained, various venereal disease pathogens can be quickly killed, venereal disease transmission is prevented, female gynecological diseases in sexual life are prevented, and inflammations such as pruritus and peculiar smell at private parts are prevented.

1. The name of this design product: Gynecological medication dispenser. 2. Purpose of this design product: used to treat gynecological diseases. 3. The key point of the design of this product lies in its shape. 4. The picture or photo that best illustrates the design points: three-dimensional picture.

The invention relates to the technical field of hygienic product absorption pads, and particularly discloses a polymer film, a preparation method thereof and application of the polymer film in the hygienic product absorption pads. The polymer film is formed by blending and processing polylactic acid and chitosan, the preparation method of the polymer film comprises the steps of preparing a chitosan solution, preparing a polylactic acid emulsion, preparing a chitosan / polylactic acid mixed solution and forming a film, the raw materials are rich, easy to obtain and low in price, the adopted raw materials are easy to degrade, the cost is low, and the polymer film is environment-friendly. And the polymer film can be effectively biodegraded, so that the later treatment of sanitary pad waste materials is facilitated, the environment is not influenced, and a good application prospect is achieved. The polymer film provided by the invention has obvious antibacterial ability, good antibacterial broad-spectrum property, and obvious antibacterial activity on candida albicans and escherichia coli, reduces bacterial breeding, improves the ability of a user to resist various gynecological diseases in the menstrual period, and ensures female health.

To provide methods for treating diseases.SOLUTION: The present disclosure provides industrially scalable methods of making (Z)-endoxifen or a salt thereof, crystalline forms of endoxifen, and compositions comprising them. The present disclosure also provides methods for treating hormone-dependent breast and hormone-dependent reproductive tract disorders. The present disclosure provides compositions and methods for the treatment and / or prevention of hormone-dependent breast and reproductive tract (gynecologic) disorders to meet the need.SELECTED DRAWING: Figure 1

The invention discloses a preparation method of a detoxification and leucorrhea arresting mixture, the mixture prepared by the method, and a quality control method and application of the mixture. The mixture is characterized in that in every 1mL of the mixture, the content of psoralen (C11H6O3) is not less than 14.89 [mu] g, and the content of astilbin (C21H22O11) is not less than 0.54 mg. The preparation method comprises the integrated steps of extracting medicinal materials, concentrating an extracting solution until the relative density is 1.06-1.10 at the temperature of 60 DEG C, standing and purifying, and adding stevioside and sodium benzoate in a specific proportion to prepare liquid and form. The invention also establishes a comprehensive quality control system covering thin-layer chromatography identification of multiple medicines including ovateleaf holly bark, pericarpium citri reticulatae, liquorice and plantain herb and content determination of the two-index components. In-vitro and clinical evidences show that the mixture has antibacterial and anti-inflammatory effects and has a good application prospect in treating gynecological diseases related to human papilloma virus (HPV) infection.

The invention provides anti-HPV (human papillomavirus) antibacterial gel as well as a preparation method and application thereof, and belongs to the technical field of medicines. Comprising the following raw materials: a saussurea involucrata extract, a centella asiatica extract, a rhodiola rosea extract, an anthocyanin extract, a modified fullerene compound, a penetration enhancing compound, carboxymethyl chitosan, carbomer, glycerol, 1, 2-pentanediol, 1, 2-hexanediol, EDTA (Ethylene Diamine Tetraacetic Acid) disodium, triethanolamine and deionized water. The anti-HPV antibacterial gel prepared by the invention effectively treats various HPV viruses and other viral gynecological diseases, solves the symptoms of peculiar smell, foreign matters, pruritus, dryness, inflammation, redness and swelling and the like, realizes long-acting antibiosis and sterilization from inside and outside cells, avoids the possibility of virus recurrence from multiple aspects, enters infected cells through cell membranes, degrades double-stranded DNA of the HPV viruses, improves the immunity, improves the defense to the viruses, and has a good application prospect. Wide application prospects are realized.

The utility model discloses a fixable vaginal speculum which comprises an expansion assembly, a locking assembly and a cleaning fluid supply assembly. The dilation assembly comprises an upper dilation piece and a lower dilation piece, and the upper dilation piece and the lower dilation piece are each of a 7-shaped structure and each comprise a dilation end and a handle end. Wherein the upper dilation piece is movably connected with the lower dilation piece, and the upper dilation piece can be switched between a first position and a second position relative to the lower dilation piece; when the upper dilation piece is switched to the first position, the dilation end of the upper dilation piece and the dilation end of the lower dilation piece are mutually folded; when the upper dilation piece is switched to the second position, the dilation end of the upper dilation piece is far away from the dilation end of the lower dilation piece; the locking assembly is arranged on the lower dilation piece and used for locking the upper dilation piece when the upper dilation piece is switched to the second position. The cleaning fluid supply assembly is communicated with the locking assembly and used for conveying cleaning fluid into the vagina through the locking assembly. According to the fixable vaginal speculum provided by the utility model, on one hand, the vaginal speculum can be fixed when the expansion assembly expands the vagina, so that the expansion assembly is kept at the expanding position and does not need to be manually held by medical personnel; on the other hand, cleaning liquid or liquid medicine can be conveyed into the vagina, so that related gynecological diseases can be treated conveniently.

The invention relates to the technical field of data management, in particular to a traditional Chinese medicine data management method and system based on big data, and the method comprises the following steps: obtaining a traditional Chinese medicine management database through a traditional Chinese medicine data management system; establishing a data management optimization model according to the traditional Chinese medicine management database, and obtaining a traditional Chinese medicine time-feature information set by using the data management optimization model; a reference evaluation index of the traditional Chinese medicine data is set, an index evaluation result of the reference evaluation index is obtained based on the traditional Chinese medicine time-feature information set, and the management system adjusts and optimizes the traditional Chinese medicine time-feature information set according to the index evaluation result to obtain a traditional Chinese medicine information target set; and analyzing the traditional Chinese medicine use condition of the hospital based on the traditional Chinese medicine information target set so as to manage and monitor the traditional Chinese medicine use data and use condition of the hospital. According to the invention, the accuracy and efficiency of data management can be improved, the normalization and safety of traditional Chinese medicine administration are promoted, and the curative effect of traditional Chinese medicine in gynecological disease treatment is grasped.

The invention discloses an antibacterial gel dressing beneficial to treatment of gynecological diseases and a preparation method thereof, and relates to the technical field of medical dressings. The antibacterial gel dressing beneficial to treatment of the gynecological diseases is prepared from an MOF material loaded with silver and copper bimetals, glycyrrhiza polysaccharide-based hydrogel, a gold nanorod hybridized MXene nanosheet composite carrier and a traditional Chinese medicine composition, a silver-copper bimetal-loaded MOF material and a gold nanorod hybridized MXene nanosheet composite carrier are attached and dispersed on glycyrrhiza polysaccharide-based hydrogel, so that the stability of a gel structure is enhanced, the adverse effect of external moisture is reduced, and meanwhile, the loading capacity of a traditional Chinese medicine composition is also remarkably improved; in addition, under the synergistic effect of the gel network, the surface active sites and the photo-thermal performance in the dressing, bacteria causing gynecological diseases are effectively killed, and the excellent antibacterial treatment effect is achieved.

Featured are methods and compositions for production of ovarian support cells. In particular, the disclosure features methods of culturing or producing ovarian support cells from pluripotent stem or progenitor cells. The ovarian support cells described herein may be used for various purposes, including the treatment of ovarian decline, infertility, and a wide array of other reproductive and gynecologic conditions, as well as for modeling particular components of the human reproductive system in order to identify and characterize new therapeutic interventions.

The invention discloses an intelligent micro-flow magnetic control biological mixed sperm robot precise targeted drug delivery method, and belongs to the technical field of biomedical engineering and micro-nano robots. The method comprises the following steps: preparing a magnetic microfluidic carrier robot with a three-dimensional multi-spiral Tesla valve structure through 3D micro-nano printing; the sperm cells and the medicine are combined through electrostatic self-assembly to form a biological mixed cluster, and the biological mixed cluster is filled into the carrier; after the micro-robot is guided into a target biological cavity, the micro-robot is driven by an external rotating magnetic field to move directionally, and medicine leakage is prevented based on unidirectivity of a Tesla valve; a medical imaging system is used for real-time positioning and tracking and guiding to a focus area, and then a magnetic field is reversed to realize quick drug release. The method is combined with artificial intelligence to achieve automatic navigation, the problem that driving performance, visibility and biocompatibility of a micro-nano robot are difficult to consider is solved, and the method has the advantages of being large in drug loading capacity, high in targeting performance, good in biocompatibility and the like and is suitable for precise treatment of gynecological diseases.