2 results about "Third-Degree Burn" patented technology

The invention discloses a method for manufacturing a large animal scald model by using laser. The method comprises the following steps: performing fasting and water-prohibiting on an experimental large animal, performing anesthesia after fasting and water-prohibiting, performing unhairing on a back experimental area after anesthesia, and performing cleaning and disinfection by using alcohol after unhairing; the method comprises the following steps: vertically facing a laser emission head of laser equipment to a back experimental area of an experimental large animal, adjusting the diameter of a laser spot to be 2cm and the output laser energy to be 20J / s, and according to different experimental large animals, adjusting the laser emission head of the laser equipment to be vertical to the back experimental area of the experimental large animal and the distance between the laser emission head and the skin epidermis of the back experimental area to be 5cm; and controlling the total energy of the output laser to complete the manufacturing of burn models from I-degree burns to III-degree burns of different experimental large animals. According to the method, the laser energy with standardized parameters is emitted by the laser equipment, so that the experimental large animal is scalded, the large animal model scald method is constructed, the operation is simple and convenient, the preparation difficulty is low, the scald grading is clear, and the consistency is relatively high.

The present invention relates to the field of biomedical materials, regenerative medicine and biotechnology, specifically to a method for producing a type I collagen solution from collagen-containing natural raw materials, and also to a method for producing a wound dressing based on type I collagen. The method for producing a type I collagen solution from collagen-containing natural raw materials does not require the use of complex equipment (in particular, centrifuges) and is therefore technologically simpler and requires less time and labor to produce type I collagen from collagen-containing natural raw materials. Moreover, said method is characterized by the short duration of the collagen extraction stage (with no need to perform a re-extraction step), as well as a high collagen yield. In addition, the type-I-collagen-based wound dressing produced using the method according to the invention is non-toxic and holds promise for the topical treatment of human skin defects, as well as for use in the case of second- and third-degree burns, and for the treatment of slow-healing shallow granulating wounds in the regeneration stage, post-traumatic wounds, trophic ulcers of any etiology or localization, bedsores, epidermolysis bullosa, and various types of pemphigus.