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39 results about "Large animal" patented technology

A method and system for detecting approach-avoidance behavior in large animals

The application discloses a kind of big animal approach avoidance behavior detection method and system, it is related to animal behavior detection technical field, including, 5 or more than 5 standard unit cage is connected in series or parallel to form combined transparent cage, according to the detection paradigm of pre-set, install grid partition, entity partition or entity partition with loose-leaf small door between adjacent unit cage;Using the overhead camera and side video recorder installed in unit cage top synchronously collects the behavior video of big animal in the combined transparent cage;After big animal is introduced into the combined transparent cage and is trained, by changing the state of partition and introducing external stimulant, trigger the approach or avoidance behavior of big animal, and use the behavior video to carry out index analysis.The application solves the problem that the existing detection device is rigid due to structure, which leads to rigid experimental paradigm and difficulty in comprehensive evaluation of complex approach avoidance behavior of animals.In addition, the prior art relies on manual observation and recording, and the analysis efficiency is low and subjective, and high-throughput automatic extraction of animal instantaneous action and fine behavior index cannot be realized.
Owner:KUNMING INST OF ZOOLOGY CHINESE ACAD OF SCI

Sterile blood sampling device for large animals

The utility model relates to the technical field of blood sampling devices for large animals, and discloses a sterile blood sampling device for large animals, which comprises a blood sampling needle, a blood sampling main pipe and a plurality of blood sampling branch pipes which are communicated in sequence, a peristaltic pump is arranged on the blood sampling main pipe, the blood sampling main pipe is communicated with a plurality of blood sampling branch pipes through a three-way pipe or a four-way pipe, the tail end of each blood sampling branch pipe is respectively connected with a blood sampling bottle, and a stop valve is arranged on each blood sampling branch pipe. According to the scheme, the peristaltic pump and the blood sampling branch pipes are combined, so that the blood sampling amount of a large animal in the end is ensured, meanwhile, the continuity of collecting blood for different project purposes is effectively improved, and the situation that the whole blood sampling amount is affected by blood coagulation and pipe blockage possibly caused by the fact that blood sampling bottles need to be switched and blood sampling is suspended in the midway is avoided.
Owner:CHONGQING AULEON BIOLOGICALS

Camera storage stand

To protect a camera and an animal so that the camera is not damaged and the animal is not injured when photographing the large-sized animal such as a bear by remote control.SOLUTION: The camera storage stand 1 includes a storage case 10 for covering and storing a camera 13, an installation stand 11 for installing the camera 13, and a leg part 12 for fixing the installation stand 11. The storage case 10 is formed in a transparent dome shape, the installation base 11 is formed in a disk shape, and the leg portion 12 is formed in a cylindrical shape. The camera 13 and the installation base 11 are fixed by coupling an attachment member 20a provided in the camera 13 and an attachment member 20b provided in the installation base 11. The storage case 10 and the installation base 11 are fixed by fixing members 14a, 14b, 14c, and 14d. The installation base 11 and the leg portion 12 are fixed to each other by coupling an attachment member 20c provided in the installation base 11 and an attachment member 20d provided in the leg portion 12.SELECTED DRAWING: Figure 1
Owner:NIPPON HOSO KYOKAI

An outdoor bait station for killing rodents

The utility model relates to mouse killing device technical field, and disclose a kind of outdoor mouse killing bait station, including fixed base plate, the fixed base plate top is fixedly arranged with mousetrap, the lower end of mousetrap is cylindrical structure, its upper end is hemispherical structure, mousetrap upper end is equipped with trap mouth, the both sides of mousetrap rotatably installed with guide ladder, the center of fixed base plate is equipped with bait installation groove, bait installation groove inside screw thread is equipped with bait placing tray. Through the four fixing holes of fixed base plate, fixed peg is used to pass through fixed hole, and the anti-pulling barb of fixed peg bottom end is inserted into soil, so as to guarantee the stability of the bait station, avoid multiple mice or larger animals to overturn the bait station, detachable guide ladder and bait placing tray, convenient for user to disassemble and preserve the bait station, at the same time, it is also convenient to wash or take and place bait, improve the use convenience of the bait station.
Owner:HUBEI KUNSIWEI PROPERTY MANAGEMENT CO LTD

Solar energy livestock GPS locator

1. The name of the design product: solar energy livestock GPS locator. 2. The use of the design product: the design product is used for positioning the location and counting the number of large animals. 3. The design points of the design product: the shape of the product. 4. The picture or photo that best indicates the design points: perspective view 1.
Owner:SHENZHEN MIJIA ELECTRONICS CO LTD

Large animal lifting and moving apparatus

A large animal lifting and moving apparatus includes a frame having a front end and a rear end, the frame, a drive shaft rotatably coupled to the frame, a drive motor coupled to the frame and operatively coupled to the drive shaft; the drive motor selectively powered by a power source, and one or more roller chains coupled to the drive shaft. The frame is structured to support a large animal between the front end and the rear end and structured to be moved during operation of the large animal lifting and moving apparatus. When the drive motor is powered by the power source, the drive motor drives the drive shaft and the roller chains coupled to the drive shaft.
Owner:KOERTGE TODD

Surface-modified aluminum hydroxide nanoparticle adjuvant as well as preparation and application thereof

The invention belongs to the technical field of preparation of vaccine immunologic adjuvants, and discloses a surface-modified aluminum hydroxide nanoparticle adjuvant as well as preparation and application thereof. The aluminum hydroxide-based adjuvant is a next-generation aluminum hydroxide-based adjuvant at an optimal level specially optimized for veterinary vaccines. The formula of the adjuvant solves the limitation of the traditional aluminum hydroxide adjuvant, including poor cellular immune induction and variable efficacy in large animals. The adjuvant promotes balanced Th1 / Th2 immune response, reduces local injection site reaction, and improves the shelf life of the vaccine. The preparation method comprises ultrasonic homogenization and co-precipitation under pH control, vaccine compositions containing the adjuvant, and uses of the adjuvant in prevention of infectious diseases in animal husbandry, companion animals and poultry. Experimental data show that in bovine respiratory disease and avian influenza models, compared with traditional adjuvants, the immunogenicity is excellent, the antibody titer is increased by 3 times, and CD8 + T cell response is enhanced.
Owner:JINZHUOJI (CHANGZHOU) BIOTECHNOLOGY CO LTD

An animal restraint device for inhalation drug delivery

An animal restraint device for inhalation drug administration comprises: a support frame consisting of multiple support legs and support plates at the top of the support legs; an animal restraint box mounted on the support plates for accommodating and restraining experimental animals; a head cover with a side opening closable to one side of the animal restraint box along its length; and a tray movably mounted on the support legs and located below the animal restraint box, the tray having sliding through holes corresponding to the support legs, the tray being slidably connected to the support legs through the sliding through holes; a support hole communicating with the sliding through hole and a fixing member disposed within the support hole on the side of the tray; a predetermined gap exists between the sliding through hole of the tray and the support leg to allow adjustment of the tray's horizontal angle by adjusting only the height of one side of the tray. This device can reduce pressure on the lungs and abdomen of large animals, improving the accuracy and stability of inhalation drug administration data for large animals.
Owner:MEDICILONMPI PRECLINICAL RES SHANGHAI

Large animal behavioristics observation cage

The utility model provides a large animal behavioristics observation cage, and relates to the technical field of animal behavioristics research, the top and the back of a movable cage are correspondingly provided with a top plate and a back plate made of transparent glass plates, other surfaces of the movable cage are formed by stainless steel woven meshes, one side of the movable cage is provided with a side separation net, and the opposite side of the movable cage is provided with an animal inlet; the animal inlet is closed through an openable door, a tray is installed at the bottom of the movable cage in an openable mode, a separation net is arranged in the middle of the front face of the movable cage, the movable cage is divided into two halves through the separation net, the separation net can be freely pulled and opened from the front face of the movable cage, and a push net is arranged in the movable cage close to one side of the animal inlet. The push rod is freely separated from or close to the front surface of the movable cage. On the premise that the number of glass faces is as large as possible and shooting of the camera is not affected, it is guaranteed that an enough large space is provided for an animal to move and stretch, natural actions such as climbing, jumping and circle turning can be shown, and operation of experimenters can be simplified.
Owner:SHENZHEN ENJI BIOTECHNOLOGY CO LTD

Automatic selection of animals to be treated during a treatment period

The disclosure relates to a sorting system for automatically selecting animals to be treated during a treatment period. A first aspect is a sorting system automatically selecting animals to be treated during a treatment period. The sorting system includes an automatic sort gate and a control arrangement receiving, via a user interface, user input indicative of sorting criteria applicable to animal properties and a maximum number of the animals allowed to be present simultaneously in the sorting area. The control arrangement is further configured to monitor a number of animals that enter and exit the sorting area. The control arrangement is finally configured to adjust one or more parameter values of the one or more sorting criteria, based on the monitored number of animals that enter and exit the sorting area. The disclosure also relates to a corresponding method and to a computer program for performing the method.
Owner:DELAVAL HLDG AB

Biological monitoring and tracking equipment for environmental ecology

The utility model discloses biological monitoring and tracking equipment for environmental ecology, relates to the technical field of monitoring equipment, and solves the technical problem that the existing technical scheme cannot track and monitor in a large range, the biological monitoring and tracking equipment comprises a main base, four traction towers are fixedly mounted on the main base, and the traction towers are arranged on the main base. The four traction towers are arranged on the base, a steel cable traction structure is arranged on the four traction towers, traction steel cables are arranged on the steel cable traction structure, and hoisting frames are connected among the traction steel cables. Wide and complex-terrain areas such as valleys, large animal botanical gardens and river valleys can be covered, and wide-area monitoring and biological tracking of the ecological environment are achieved; the position of the monitoring camera can be flexibly adjusted, the technical bottleneck that traditional fixed monitoring equipment is limited by terrains and distances and the monitoring range is limited is broken through, and the flexibility and effectiveness of ecological monitoring are greatly improved.
Owner:WUXI INST OF ARTS & TECH

Modularized wild animal transport case suitable for different species

The invention relates to a modular wild animal transport case suitable for different species, and belongs to the technical field of auxiliary animal transport equipment, the modular wild animal transport case mainly comprises a plurality of sub-bins which can be detachably assembled, and the sub-bins can be combined into terrestrial bins and aquatic bins to realize partitioned transport of land and water species. The first terrestrial bin is matched with large animals, the bin bottom is a steel fence, and the second terrestrial bin drives a sliding body through a lead screw to drive an isolation plate to move horizontally and can be flexibly divided into spaces of different sizes to be matched with small animals of different sizes. And a sewage discharge bin is arranged below each terrestrial bin, so that sewage isolation and collection are realized. The bin doors are oppositely arranged to avoid animal disturbance, the air inlet channel guarantees air circulation in the bin, the lead screw is provided with scales and can be clamped and fixed, and the isolation plate is detachable and is provided with a positioning structure. The device can flexibly meet the transportation requirements of animals of different species and different body types, the transportation efficiency and the animal comfort degree are improved, cleaning is convenient, fixing is reliable, the structure is modularized, independent installation and use are achieved, and practicability is high.
Owner:广元市野生动植物保护管理站

Urine collecting device

The utility model relates to a urine collecting device. The urine collection device comprises a first rod piece, a stimulation element, a second rod piece and a collection mechanism. The stimulation element is arranged on the first rod piece and used for stimulating the animal to urinate. The second rod piece is detachably arranged on the first rod piece. The collecting mechanism is arranged on the second rod piece and used for collecting urine of animals. According to the urine collecting device, the urination desire of a large animal can be increased, the urination speed of the large animal is higher, the waiting time is shortened, the urine of the large animal can be collected through the collecting mechanism, and the urine collecting device is more convenient to carry and use.
Owner:GUANGDONG CHIMELONG GRP CO LTD

Spine holder for two-photon recording

The utility model provides a spine holder for two-photon recording, comprising: a first support comprising a first clamping arm arranged along a first direction, a first extension plate arranged along the first direction and connected with the first clamping arm, and a first connecting plate arranged along a second direction, the first connecting plate being connected with the first extension plate; the second support comprises a second clamping arm arranged in the first direction, a second extending plate arranged in the first direction and connected with the second clamping arm and a second connecting plate arranged in the second direction, and the second connecting plate can be connected with the first connecting plate in a sliding mode in the second direction; and the lead screw is arranged in the second direction and connected with the first extending plate and the second extending plate, and the lead screw and the clamping space are located on the two opposite sides of the first connecting plate and the second connecting plate in the first direction correspondingly. The spine clamp holder is high in structural strength and structural stability, and not only can adapt to spine structures of small animals, but also can adapt to spine structures of large animals.
Owner:SHENZHEN INST OF ADVANCED TECH CHINESE ACAD OF SCI

Combined type large animal negative pressure protection suction exposure restraint device

The utility model relates to a combined type large animal negative pressure protection inhalation exposure restraint device, and relates to the technical field of inhalation exposure animal restraint devices, the combined type large animal negative pressure protection inhalation exposure restraint device comprises a mask, a negative pressure head cover box and a fixing vehicle, the mask comprises an airflow channel and a cover body communicated with the airflow channel, and the cover body is provided with an extraction opening in a communicated mode; an elastic fixing sleeve with a neck opening is arranged on the side, away from the airflow channel, of the cover body. The negative pressure hood box is used for containing a mask and comprises a box body and a flexible neck sleeve communicated with the box body, and a negative pressure extraction opening is formed in the box body; the fixing vehicle comprises a vehicle frame, an abdomen supporting platform and a leg supporting platform, the abdomen supporting platform and the leg supporting platform are sequentially arranged in the vehicle frame from top to bottom, the negative pressure head cover box is hinged to one end of the top of the vehicle frame, leg holes for legs of the experimental animal to penetrate through are formed in the abdomen supporting platform, and binding holes for binding and fixing four limbs of the experimental animal are formed in the leg supporting platform. By arranging the fixing device capable of stably fixing the large animal, the requirement of the large animal inhalation exposure experiment is met.
Owner:BEIJING HUIRONGHE TECH

SgRNA targeting mstn gene and application thereof in constructing cat myostatin gene knockout model

PendingCN122357549ABiotechnologyDisease
This invention discloses a targeted MSTN The sgRNA of the gene and its application in constructing a feline myostatin gene knockout model; the targeted MSTN The nucleotide sequence of the gene's sgRNA is shown in SEQ ID NO.1 and / or SEQ ID NO.2. This invention systematically establishes a CRISPR / Cas9 genome editing platform suitable for domestic cats for the first time and successfully constructs the world's first... MSTN The gene knockout live model in domestic cats represents a breakthrough in the technical barriers to functional gene research in domestic cats. It has been demonstrated that sgRNA is a highly efficient editing tool for the MSTN gene in domestic cats. The constructed... MSTN The gene knockout domestic cat model provides an unprecedented tool for in-depth research on muscle biology and muscle diseases in mammalian (cat) systems that are more closely related to humans. It fills the gap in large animal models in this field and has significant value for basic scientific research and translational medicine.
Owner:YANGZHOU UNIV

Fixing device for blood sampling of middle and large animals

The utility model discloses a fixing device for blood collection of medium and large animals, and relates to the technical field of animal blood collection. The device comprises a fixing table, channels are formed in the two sides of the top of the fixing table, and an inductor is fixedly connected to the top of the fixing table; a fixing assembly is arranged in an inner cavity of the fixing table and comprises a two-way lead screw, and the two-way lead screw is movably connected to the inner cavity of the fixing table. Through the arrangement of the inductor, the movement of the electric push rod can be automatically triggered after an animal steps on the inductor, the electric push rod enables the driving gear on the surface of the worm to be meshed with the driven gear by pushing the push block, and under the driving of the motor, the driving gear and the driven gear can be matched to drive the bidirectional lead screw to rotate; the rotation of the bidirectional lead screw further drives the arc-shaped plate at the top of the sliding sleeve to move, so that the animal limbs are accurately fixed and are ensured to be limited at specified positions at the top of the fixing table.
Owner:SUZHOU LIZE BIOTECHNOLOGY CO LTD

System for implementing the respiratory calorimetry function of large animals and method thereof

This invention relates to a system for measuring the respiratory calorimetry of large animals, comprising an artificial climate chamber, a controller, and a ventilation fan. The artificial climate chamber serves as the activity area for the test animals, used to regulate and simulate environmental conditions and monitor animal status. The controller is connected to the artificial climate chamber to coordinate the environmental simulation, collect physiological and behavioral data of the animals, and collect gas concentration measurements. The ventilation fan is connected to the ventilation and sampling pipeline of the artificial climate chamber to drive ventilation. The system and method for measuring the respiratory calorimetry of large animals using this invention accurately simulate various animal growth environmental conditions, resolving measurement errors caused by evaporation and splashing from large animal drinking troughs. The structure of the timed and quantitative feeder, feed trough, and weighing sensor provides dual verification of animal feed intake, resolving feed intake measurement errors. The use of a dry-wet separation sewage system solves the problem of metabolic measurement errors caused by air leakage at the sewage outlet.
Owner:SHANGHAI TOW INTELLIGENT TECH CO LTD

Collaborative laser deinsectization unmanned aerial vehicle combination with animal recognition system

The invention discloses a cooperative laser deinsectization unmanned aerial vehicle combination with an animal recognition system, which comprises an air unmanned aerial vehicle and a land unmanned aerial vehicle, a connecting assembly is arranged between the air unmanned aerial vehicle and the land unmanned aerial vehicle, a clamping box is arranged above the land unmanned aerial vehicle, a clamping block is arranged below the air unmanned aerial vehicle, and the clamping block is connected with the clamping box. The clamping block is arranged in the clamping box, a plurality of locking grooves are formed in the inner side wall of the clamping box, a plurality of telescopic locking rods are arranged in the clamping block, one ends of the locking rods penetrate through the clamping block, the ends, penetrating through the clamping block, of the locking rods are meshed with the locking grooves, and an aerial laser insect killer is arranged on one side of the aerial unmanned aerial vehicle. The invention belongs to the technical field of deinsectization, and particularly provides a deinsectization system which recognizes and distinguishes insect bodies and large animals through a thermal imager, emits laser through a laser deinsectization device for removal, shares data through an aerial unmanned aerial vehicle and a land unmanned aerial vehicle, and realizes deinsectization. And the cooperative laser deinsectization unmanned aerial vehicle combination with the animal identification system can independently identify animals and perform laser deinsectization operation.
Owner:RIYUESHENG (DALIAN) ENVIRONMENTAL PROTECTION TECHNOLOGY CO LTD

Large animal restraint structure for veterinary use

The utility model relates to the field of animal husbandry and veterinary technology, especially to a large animal binding structure for animal husbandry and veterinary, which comprises a lifting mechanism for adjusting the height of an animal, and a fixing mechanism for fixing the limbs of the animal is installed on the lifting mechanism. The utility model sets the lifting mechanism and the fixing mechanism, when using the device, four clamping assemblies are installed on the appropriate position of the placing plate according to the distance of the limbs of the animal, then the second electric push rod is controlled to extend, the second electric push rod drives the movable plate and the clamping assembly to move, the clamping assembly is fixed by the movement of the clamping block, the animal is placed on the placing plate according to the position of the four clamping assemblies, then the limbs of the animal are fixed by the four clamping assemblies, then the first electric push rod is controlled to retract, the first electric push rod drives the animal to rise, and the animal can be examined and treated after rising to the appropriate height.
Owner:会泽县大海乡农业农村综合服务中心(会泽县大海乡集体三资管理办公室)

Died livestock and poultry treatment all-in-one machine based on biological inactivation technology

The invention discloses an all-in-one machine for treating livestock and poultry died of illness based on a biological inactivation technology, belongs to the technical field of treatment of livestock and poultry died of illness, and aims to solve the problems that in a traditional treatment mode, high-temperature steam is difficult to penetrate through internal tissues of large animal carcasses, core sterilization is not thorough, and biological potential safety hazards exist. A plurality of isolation plate assemblies are rotationally connected into the sealing tank assembly, radial cutting assemblies are connected to the multiple isolation plate assemblies, any two adjacent isolation plate assemblies are connected through a connecting pipe, a dead body is decomposed into fragments through the radial cutting assemblies, the specific surface area is increased through geometric progression, steam is made to penetrate through tissue more easily, and meanwhile, the steam can penetrate through the tissue more easily. The contact pin assembly synchronously pierces into meat blocks during cutting to form dense micropore channels and become a high-speed path for steam to diffuse to a core part, and the driving assembly drives fragments to rotate at a high speed to form a three-dimensional turbulent flow field, so that steam is forced to penetrate through a cutting section and micropores, and sterilization dead angles are eliminated.
Owner:JIANGSU BIG DIPPER ENVIRONMENTAL PROTECTION CO LTD

Method for manufacturing large animal scald model by using laser

PendingCN121754336AClimate change adaptationSurgical veterinaryFirst-Degree BurnBiology
The invention discloses a method for manufacturing a large animal scald model by using laser. The method comprises the following steps: performing fasting and water-prohibiting on an experimental large animal, performing anesthesia after fasting and water-prohibiting, performing unhairing on a back experimental area after anesthesia, and performing cleaning and disinfection by using alcohol after unhairing; the method comprises the following steps: vertically facing a laser emission head of laser equipment to a back experimental area of an experimental large animal, adjusting the diameter of a laser spot to be 2cm and the output laser energy to be 20J / s, and according to different experimental large animals, adjusting the laser emission head of the laser equipment to be vertical to the back experimental area of the experimental large animal and the distance between the laser emission head and the skin epidermis of the back experimental area to be 5cm; and controlling the total energy of the output laser to complete the manufacturing of burn models from I-degree burns to III-degree burns of different experimental large animals. According to the method, the laser energy with standardized parameters is emitted by the laser equipment, so that the experimental large animal is scalded, the large animal model scald method is constructed, the operation is simple and convenient, the preparation difficulty is low, the scald grading is clear, and the consistency is relatively high.
Owner:EPINTEK +1

Three-dimensional mixed breeding poultry cage

The utility model relates to the technical field of poultry breeding, and discloses a three-dimensional mixed breeding poultry cage which comprises a bearing plate, the bottom of the front side of the bearing plate is fixedly connected with a bottom plate, the middle lower portion of the front side of the bearing plate is fixedly connected with a lower middle-layer plate, and the middle upper portion of the front side of the bearing plate is fixedly connected with an upper middle-layer plate. The top of the left side and the top of the right side of the bottom plate are fixedly connected with side net plates, the rear sides of the side net plates are rotationally connected with rotating columns, the tops of the side net plates are fixedly connected with a top net plate, and the front end of the right side of the bottom plate is fixedly connected with a first hollowed-out column. According to the cage, when poultry animals are bred, quails and parrots can be placed on the middle-layer plate on the upper layer of the cage, large animals are placed on the bottom plate, the middle-layer plate on the lower portion of the cage and the side net plates to prevent escaping, the cage can be opened to be convenient to clean, the cage is fixed through the limiting buttons and the second net door and screwed through the rotary knobs, and feeding is simplified and resource complementation is promoted through the mixed breeding method.
Owner:HAINAN QUANJIAN LUHENG ECOLOGICAL AGRICULTURE DEVELOPMENT CO LTD

Kit and method suitable for Golgi staining of large animals

The invention relates to a kit and a method suitable for Golgi staining of large animals. The kit comprises: 1) an impregnation liquid, wherein the impregnation liquid is an AB liquid, and the AB liquid is an isovolumetric mixed liquid of 5 wt% potassium dichromate (liquid A) and 5 wt% mercuric chloride (liquid B); the solution C is 1.4 wt% potassium chromate solution, the color developing solution is a mixed solution of a solution D, a solution E and flushing fluid in a volume ratio of 1: 1: 1.8-1: 1: 2.5, and the solution D is a mixed solution of 25vol% stronger ammonia water and Milli-Q water; the solution E is a sodium thiosulfate pentahydrate aqueous solution; and the flushing fluid is Milli-Q water. Methods of Golgi staining of large animal brain tissue are also provided. According to the method, high-definition and quantitative-analysis staining results are provided for neuroscience research of the domestic dogs, and reference is provided for optimization of Golgi staining technologies of other large animals.
Owner:KUNMING INST OF ZOOLOGY CHINESE ACAD OF SCI

Large animal model of traumatic optic neuropathy

A method for constructing a clinically-relevant large animal model of traumatic optic neuropathy, employing a goat with orbital anatomy and optic nerve structure similar to humans as a model animal, overing the defects existing in other animals as TON model animals. The target model goat is obtained by screening parameters, such as a maximum transverse diameter of a coronal plane of a body of sphenoid bone and a wall width of a sphenoid bone, thereby facilitating the exposure of an optic nerve in a optic-canal segment under a nasal endoscopic surgery and quantitative injury. With the optic nerve injury animal model, the clinical TON pathogenesis can be explored by studying the optic nerve at the injured optic canal. In the prepared TON animal model, the injured optic nerve is closer to the brain, which is beneficial to rebuilding the synaptic connection.
Owner:THE EYE HOSPITAL OF WENZHOU MEDICAL UNIVERSITY

Application of IL10 gene editing in inflammatory bowel disease pig model

PendingCN121653191AHydrolasesPeptidesGene knockdownBowels diseases
The invention discloses an application of IL10 gene editing in an inflammatory bowel disease pig model. The gene editing is selected from gene knockout, gene knockdown, gene interference or gene point mutation capable of inactivating or reducing IL10 gene expression. It is proved for the first time that the IL10 <- / -> pigs obtained through gene editing can spontaneously suffer from enteritis in a conventional feeding environment, and a research tool closer to human physiological characteristics is provided; the IL10 < + / -> pig has no obvious inflammatory bowel disease phenotype in a conventional environment, the cost of model cultivation and propagation can be effectively reduced, a large animal model of the inflammatory bowel disease can be obtained through conditions induction and the like when needed, and different research requirements can be flexibly met; the IL10 < + / -> pig can be used as a model for researching IBD pathogenesis inducements and related mechanisms of people with low IL10 expression.
Owner:CHONGQING ACAD OF ANIMAL SCI

Injection dosing device for large animals

The utility model relates to the technical field of injection administration, and discloses an injection administration device for large animals, which comprises a connecting seat, the outer wall of the connecting seat is fixedly connected with a connecting rod I, one end of the connecting rod I is provided with a pushing assembly, the inner wall of the connecting seat is provided with a connecting assembly, the pushing assembly comprises a connecting rod II, and the connecting rod II is fixedly connected with the connecting rod II. One end of the second connecting rod is rotationally connected to one side of the inner wall of the first connecting rod, a rotating rod is rotationally connected into the first connecting rod, the outer wall of the rotating rod is sleeved with a spring, and a clamping block is fixedly connected to one side of the inner wall of the second connecting rod. According to the utility model, an operator can accurately change the position of the adjusting screw block on the push rod by rotating the adjusting screw block, so that in the injection process, when the push rod pushes the piston to move forwards and reaches the position of the adjusting screw block, the piston is limited to move forwards continuously, and the injection dosage is accurately controlled; and dose errors caused by different manual pushing forces and feelings are avoided.
Owner:OPEN UNIVERSITY OF CHINA

Mountain area large animal intelligent monitoring system based on multi-light image fusion

The invention discloses a mountainous area large animal intelligent monitoring system based on multi-light image fusion, and relates to the technical field of interactive early warning, the mountainous area large animal intelligent monitoring system comprises a monitoring center, the monitoring center is connected with a sensing acquisition module, a fusion processing module, an early warning analysis module and an intelligent regulation and control module; the method comprises the following steps: acquiring environment tense information of a patrol coverage area of operation and maintenance personnel, constructing a patrol holographic situation map, and performing multi-light extraction on the environment tense information to obtain a visible light image and a thermal infrared image; performing dual identification on the visible light image and the thermal infrared image, and identifying selected point species; performing animal positioning on the operation and maintenance personnel based on the selected point species to obtain an animal threat distance, performing risk level evaluation on the animal threat distance, and generating a risk-avoiding self-protection scheme of the operation and maintenance personnel according to an evaluation result; active early warning is achieved, danger avoiding time is won, and the detection rate is ultrahigh and the false alarm rate is extremely low.
Owner:YANBIAN ELECTRICAL BUREAU +1

Large animal shearing machine

The invention relates to a large animal shearing machine with a shearing machine body comprising a drive unit having an electric motor and a shearing machine head comprising a shearing head holder for the detachable receiving of a shearing head having a first cutting plate and a second cutting plate, wherein the shearing machine head is connected to a motor output shaft of the electric motor and is designed to convert the rotary motion of the motor output shaft into an oscillating motion of the first cutting plate relative to the second cutting plate.In order to provide a large animal shearing machine that is cost-effective to manufacture, comfortable to handle, and allows for easy shearing head replacement, the shearing head holder on the shearing machine head is designed to be adjustable between a mounting position for positioning and removing the shearing head and an operating position, and the longitudinal axis of the motor output shaft, a longitudinal axis of an eccentric shaft coupled to the motor output shaft, and a pivot axis of a rocker arm driven by the eccentric shaft and engaged with the first cutting plate in the operating position are aligned parallel to each other.
Owner:AESCULAP SCHERMASCHINEN GMBH

Animal operation platform used under field operation condition

The animal operation platform used under the field operation condition comprises a lying plate, a plurality of sets of supporting angle plates are symmetrically arranged on the outer walls of the two sides of the lying plate, side plates are symmetrically arranged on the inclined faces of the supporting angle plates on the two sides, and two sets of installation rods are symmetrically arranged at the two ends of the lower surface of the lying plate. A plurality of operators can hold the four-corner holding rings to quickly move, so that the flexibility is improved. After the animal is moved to a proper position, the injured animal is placed on the lying plate, a binding belt penetrates through a retaining ring to be bound, meanwhile, the animal is limited through a side plate, a stable environment is created for an operation, aiming at a large animal, the extension rod is turned over after binding, the rod extrudes the inclined surface of the clamping rod to enable the clamping rod to move upwards, the spring is pressed, and the spring rebounds after the rod is turned over to enable the clamping rod to be inserted into the clamping groove to be locked. The pin penetrates through the through hole of the extension rod and is nailed into the ground, so that the supporting area and stability are increased, shaking and displacement caused by animal struggling are prevented, and smooth operation is guaranteed.
Owner:THE 32237TH UNIT OF THE PEOPLES LIBERATION ARMY OF CHINA