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Rhododendron nivale Hook. f. volatile oil and application thereof

A snow-covered Rhododendron and volatile oil technology is applied in the directions of essential oils/spice, medical preparations containing active ingredients, plant raw materials, etc., which can solve problems such as drug residues and achieve good therapeutic effects.

Active Publication Date: 2015-06-03
LANZHOU INST OF ANIMAL SCI & VETERINARY PHARMA OF CAAS
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the drugs used to treat animal mites are mainly chemically synthesized and antibiotic drugs, such as ivermectin, mite net, etc. While these drugs can effectively prevent and treat animal mites, they have caused public health problems due to drug residues. , food safety and ecological environment

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] The preparation method of Rhododendron snow layer volatile oil of the present invention is as follows:

[0021] After drying the fresh stems and leaves of Rhododendron vulgaris, weigh 100g of dried Rhododendron vulgaris stems and leaves, put them into a volatile oil extractor, add 1500mL of distilled water, soak for 8 hours, and extract by distillation for 8 hours until the volume of volatile oil does not increase any more. Go to the upper layer to get volatile oil. The yield was 2.01%.

Embodiment 2

[0023] The preparation method of Rhododendron snow layer volatile oil of the present invention is as follows:

[0024] After drying the fresh Rhododendron glabra stems and leaves in the shade, weigh 100g of dried Rhododendron glabra stems and leaves, put them into a volatile oil extractor, add 1700mL of distilled water, soak for 10 hours, and distill and extract for 12 hours until the volume of volatile oil does not increase any more. Go to the upper layer to get volatile oil. The yield was 2.23%.

Embodiment 3

[0026] The preparation method of Rhododendron snow layer volatile oil of the present invention is as follows:

[0027] After drying the fresh Rhododendron glabra stems and leaves in the shade, weigh 100g of the dried Rhododendron glabra stems and leaves, put them into a volatile oil extractor, add 2000mL of distilled water, soak for 14 hours, and distill and extract for 14 hours until the volume of volatile oil does not increase any more. Go to the upper layer to get volatile oil. The yield was 2.43%.

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PUM

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Abstract

The invention provides Rhododendron nivale Hook. f. volatile oil which is prepared through the following steps: adding 15-20-fold water to dry Rhododendron nivale Hook. f., soaking for 8-14h, performing distillation extraction for 10-14h until the volume of volatile oil is not increased any more, standing still, and removing supernatant. The invention further provides application of the Rhododendron nivale Hook. f. volatile oil in preparation of a medicine for treating animal acariasis. The maximum yield of the Rhododendron nivale Hook. f. volatile oil is 2.45%; and 76 kinds of compounds are obtained by an improved GC-MS chromatographic method. The Rhododendron nivale Hook. f. volatile oil provided by the invention has a favorable therapeutic effect on animal acariasis, is of medicine concentration independence, and can be used for treating animal acariasis.

Description

technical field [0001] The invention relates to a kind of volatile oil of rhododendron azalea. Background technique [0002] Rhododendron snow layer ( Rhododendron nivale Hook. f.) is a small evergreen shrub of Rhododendronaceae Rhododendron, distributed in the southeast, south, east and northeast of Tibet, China. It is also distributed in Nepal, India, Bhutan, and Sikkim. Born in alpine shrubs, glacier valleys, meadows, 3200-5800 meters above sea level. The twigs and leaves of Rhododendron snow can be used for antitussive and expectorant. But no one has conducted research on its chemical composition and pharmacological activity. [0003] Animal acariasis is a chronic ectoparasitic disease of animals caused by mites parasites on the surface. It mainly occurs in late autumn, winter and early spring. It is infected through direct or indirect contact between sick animals and healthy animals. It widely occurs in cattle, sheep, Animals such as horses, dogs, rabbits, and chi...

Claims

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Application Information

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IPC IPC(8): C11B9/02G01N30/02A61K36/45A61P33/14
CPCA61K36/45A61K2236/331C11B9/027G01N30/02
Inventor 郭肖尚小飞张继瑜李冰文豪
Owner LANZHOU INST OF ANIMAL SCI & VETERINARY PHARMA OF CAAS
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