Pharmaceutical composition for treating premenstrual tension syndrome and preparation method thereof

A composition and syndrome technology, which is applied in the field of pharmaceutical compositions for treating premenstrual tension syndrome, and can solve problems such as lack of drugs

Inactive Publication Date: 2015-07-15
北京植物世纪营养品有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, Chinese patent medicines are also used in treatment, among which the most widely used are Jiawei Xiaoyao Pills, Chaihu Shugan Powder, Longdan Xiegan Pills, Anti-Brain Failure Capsules, Xuefu Zhuyu Capsules, etc., but there are relatively few targeted therapeutic drugs

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] Preparation of pharmaceutical composition granules of the present invention (based on 1000 daily doses per person):

[0030] Weigh 5 kg of Bupleurum bupleuri, 5 kg of gardenia, 5 kg of turmeric, and 5 kg of Cyperus cyperi, add 70% ethanol to reflux extraction for 3 times, each time for 1 hour, filter, combine the filtrates, and recover ethanol under reduced pressure; weigh 5 kg of white peony root, malt 8kg, Leulu 5kg, Angelica 5kg, Jiangpinellia 5kg, Beiliu Jinu 6kg, Radix Glycyrrhizae 2kg add water and extract 3 times, each time for 1 hour, filter, combine with the above concentrated solution, concentrate, dry, crush into fine powder, add Mix lactose and dextrin, use 90% ethanol solution as wetting agent, granulate and dry to make granules.

Embodiment 2

[0032] Preparation of pharmaceutical composition granules of the present invention (based on 1000 daily doses per person):

[0033] Weigh 10kg Bupleuri, 10kg Gardenia, add 60% ethanol to reflux and extract twice, each time for 1.5 hours, filter, combine the filtrates, and recover ethanol under reduced pressure; weigh 15kg malt, 9kg Loulu, 9kg Beiliu Jinu, add water Extract 2 times, 1.5 hours each time, filter, combine the filtrates, concentrate, add alcohol to 50% alcohol content, let stand overnight, centrifuge, discard the precipitate, recover ethanol from the supernatant under reduced pressure, combine with the above concentrated solution, Concentrate, dry, crush into fine powder, add aspartame and dextrin and mix well, use 70% ethanol solution as wetting agent, granulate and dry to make granules.

Embodiment 3

[0035] Preparation of pharmaceutical composition capsules of the present invention (based on 1000 daily doses per person):

[0036] Weigh 1 kg of Bupleurum bupleuri, 2 kg of gardenia, 2 kg of Cyperus cyperi, add 80% ethanol to reflux extraction once, 2 hours, filter, combine the filtrates, recover ethanol under reduced pressure; weigh 2 kg of white peony root, 3 kg of malt, 2 kg of leaking reed, Ginger Pinellia 1kg, Bei Liu Jinu 2kg, Radix Glycyrrhizae 1kg add water to extract once, filter for 2 hours, combine with the above concentrated solution, concentrate, dry, grind into fine powder, add dextrin and mix well, add PVPK30 ethanol solution to moisten agent, granulated, dried, filled into capsules, and made into capsules.

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PUM

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Abstract

Premenstrual syndrome (PMS) refers to a group of symptom complex repeatedly occurring 7-14 days before menstruation (namely in a luteal phase of a menstrual cycle), affecting women daily life and work and relating to bodies, spirit and behavior, the symptom disappears naturally after menses, and about 90% of women of child-bearing age are estimated to have at least one PMS. The invention aims to provide a pharmaceutical composition for treating premenstrual tension syndrome and a preparation method thereof. The pharmaceutical composition is composed of radix bupleuri, cape jasmine, malt, radix rhapontied and siphonostegia chinensis. The pharmaceutical composition has the functions of soothing liver and relieving depression, regulating qi to alleviate pain, and promoting blood circulation to regulate menstruation, and is used for liver qi unfavorable prognosis syndrome of the premenstrual tension syndrome. The preparation method of the pharmaceutical composition comprises the steps: extracting and concentrating the pharmaceutical composition with water or an appropriate concentration of ethanol or concentrating after recovery of the ethanol, removing impurities, drying, mixing with suitable auxiliary materials, and preparing a pharmaceutically acceptable preparation.

Description

technical field [0001] The invention relates to a pharmaceutical composition for treating premenstrual tension syndrome and a preparation method thereof. Background technique [0002] Premenstrual syndrome (PMS) refers to a group of symptoms that repeatedly occur 7 to 14 days before menstruation (that is, in the luteal phase of the menstrual cycle), affect women's daily life and work, and involve both physical and mental (emotional, behavioral) aspects. Syndrome, after menstrual cramps, symptoms disappear naturally. It is more common in women of childbearing age aged 30 to 40. It is estimated that about 90% of women of childbearing age have at least one PMS symptom, of which 20% to 30% have moderate to severe symptoms, and 2% to 10% have severe symptoms. The American Psychiatric Association refers to the severe form of PMS as premenstrual dysphoric disorder (PMDD). The World Health Organization (WHO) defines PMS as a group of physical, emotional and cognitive symptoms that...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8998A61K36/9066A61P15/00
Inventor 申春悌赵晓霞赵祥
Owner 北京植物世纪营养品有限公司
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