A wireless passive drug targeting drug delivery device

Abstract

The invention provides a wireless passive drug targeting administration device, and belongs to medical equipment. The device comprises a shell. The device is characterized in that a top cover is disposed on the top of the shell, and a drug storage chamber is arranged in an inner cavity of the shell; a magnetostrictive bar, a guide rod and a catheter are arranged in the drug storage chamber; the top cover is connected with one end of the guide rod, and the other end of the guide rod is arranged in the catheter; the catheter is connected with a bottom plate of the drug storage chamber, and crawling feet made of magnetostrictive materials are disposed on the lower side of the shell. An adjustable constant or alternating current source is adopted, a drug transport car is placed in a helmholtz coil, and alternating current and direct-current bias can be provided. By adjusting the magnitude of constant current and the frequency and the direction of the alternating current, the frequency and the amplitude of a magnetostrictor are adjusted, and the function of targeting administration is achieved. Besides, the release process of drugs carried on the drug transport car can be manually controlled. The dosage of the carried drugs can be increased to the largest extent under the condition that drug properties of the carried drugs are not damaged, and the drug transport car has no energy source itself.

Description

technical field [0001] The invention belongs to medical equipment, in particular to a wireless passive drug targeting drug delivery device. Background technique [0002] A nano drug molecular transport vehicle that can pass through human organs and blood vessels has been successfully developed in Shanghai. The diameter of this transport vehicle is only 200 nanometers (1 / 300 of the diameter of a hair). This method of drug delivery can not only give full play to the effectiveness of the drug, but also only target the affected area without harming other tissues. It is not only harmless to the human body, but also can pass freely in organs and blood vessels. Its shape is like a sphere full of regular small holes, and the medicine is packed in the small holes. It usually wears an "organic coat" and contains a "magnetic navigator" composed of ferric oxide particles in the middle. Under the effect of a magnetic field outside the body, The transport vehicle will arrive at the affe...

AI Technical Summary

Problems solved by technology

Patent CN101148194A provides the "double-tailed super-magnetic bionic robot fish" and patent CN202691444U provides the "semi-closed vibrating micro-pipe robot". The technical solution of controllable release at the lesion

In addition, the Chinese patent "a micro-device acting on target cells" with the application date of 2013.12.31 and the application number of 201310746458.7 is essentially a drug delivery vehicle. However, due to the heat emitted by the heat-releasing needle, the properties of the medicine carried by some drug transport vehicles will change, which cannot achieve the function of treating lesions, and the patent does not describe in detail how the drug vehicle drives away from the human body. Driving away from the human body, because the micro-device is directional, it needs to turn the head and tail in the small blood vessels, so not only its volume is limited to a certain extent, the amount of medicine it carries may not meet the dose required for treatment, and its The shell is in the shape of a pentagonal pyramid, which is easy to scratch the surface of blood vessels and cause unnecessary harm

In addition, it contains multiple transmission devices inside, and the structure is also complicated

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