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Orifice-opening rhinitis capsule and preparation method thereof

A technology of Tongqiao rhinitis capsules and rhubarb, which is applied in the directions of capsule delivery, pharmaceutical formulations, and medical preparations containing active ingredients, etc., can solve the problems of unsatisfactory effect and low local drug concentration.

Inactive Publication Date: 2015-11-18
高秀婷
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the effect of oral Chinese medicine is not satisfactory because of the low local drug concentration.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0084] Preparation of Tongqiao rhinitis capsules.

[0085] (1) In parts by weight, take 2 parts of small rhubarb, 10 parts of ?-blow fire tube, 9 parts of amaranth, 8 parts of pond snake, 4 parts of oxtail, 3 parts of ganbangui, 1 part of full rice flowers, branches and leaves, ground skeleton 9 parts, 7 parts of Momordicae Root, 4 parts of Fish Herbs, 10 parts of Radix Glycyrrhiza, 2 parts of Red Shank Powder, 3 parts of Radix Glycyrrhiza, add 8 times the amount of 70% ethanol, soak for 24 hours, extract by reflux for 2 hours, filter, and remove the residue Add 6 times of 70% ethanol for reflux extraction for 1 h, filter, combine the extracts, recover ethanol and concentrate under reduced pressure (temperature 55 °C, vacuum degree 0.07~0.08MPa) to a thick liquid with a relative density of 1.20~1.30 (60 °C). The paste is dried under reduced pressure (temperature 60~70℃, vacuum degree 0.08~0.09MPa) to obtain dry paste;

[0086] (2) Take 3 parts of green rabbit ear wind, 5 part...

Embodiment 2

[0090] Preparation of Tongqiao rhinitis capsules.

[0091] (1) In parts by weight, take 4 parts of small rhubarb, 12 parts of chimney, 11 parts of amaranth, 10 parts of pond snake, 6 parts of oxtail, 5 parts of ganbangui, 3 parts of full rice flowers, branches and leaves, ground skeleton 11 parts, 9 parts of Momordicae Root, 6 parts of Fish Herbs, 12 parts of Shan Deng Cai, 4 parts of Red Shank Powder, 5 parts of Shan Kun, add 8 times the amount of 70% ethanol, soak for 24 hours, reflux for 2 hours, filter, residue Add 6 times of 70% ethanol for reflux extraction for 1 h, filter, combine the extracts, recover ethanol and concentrate under reduced pressure (temperature 55 °C, vacuum degree 0.07~0.08MPa) to a thick liquid with a relative density of 1.20~1.30 (60 °C). The paste is dried under reduced pressure (temperature 60~70℃, vacuum degree 0.08~0.09MPa) to obtain dry paste;

[0092] (2) Take 5 parts of green rabbit ear wind, 7 parts of sheep ear garlic, 3 parts of Guangxi cr...

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Abstract

The invention discloses an orifice-opening rhinitis capsule and a preparation method thereof. The orifice-opening rhinitis capsule mainly comprises raw materials as follows: Rheum pumilum Maxim., twigs and leaves of Taperleaf Japanese Spiraea, amaranth, herb of creeping waterprimrose, meadow fescue, perforate fleeceflower, Vaccinium laetum Diels, old radish roots, roots of Cochinchina Momordica, herb of apple mint, Lobelia sessilifolia Lamb., Polygonum runcinatum, hance pepper stems and leaves, herb of Rednerve Ainsliaea, roots of Japanese Dock, Lysimachia alfredii, Notholirion bulbuliferum, all-grass of Foliosous Parnassia, herba cistanches, barks of Sorbus pohuashanensis and the like. The orifice-opening rhinitis capsule is prepared with an advanced extraction and preparation process, and the capsule can effectively cure chronic simple rhinitis.

Description

technical field [0001] The invention relates to the field of capsule preparations, more specifically, the invention relates to a Tongqiao Biyan capsule and a preparation method thereof. Background technique [0002] Chronic rhinitis is a common disease in the Department of Otorhinolaryngology, and it is a chronic inflammatory nasal disease of the nasal mucosa and submucosa caused by various reasons. The disease is closely related to the environment, climate, constitution, etc. The course of the disease is long and lingering and difficult to heal. The main symptoms and signs are nasal congestion, runny nose, olfactory disturbance, turbinate congestion and swelling, etc. There is no ideal method for treatment. Especially for topical administration in the nasal cavity, some traditional western medicine nasal drops, commonly used are cyclic amines (such as ephedrine), chain amines and imidazoles (such as dripping nasal net), mainly by shrinking the subepithelial blood vessels of...

Claims

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Application Information

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IPC IPC(8): A61K36/899A61K36/898A61K9/48A61P11/02
Inventor 不公告发明人
Owner 高秀婷
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