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Cardamom extract, preparation containing cardamom extract, and application of cardamom extract in treatment of obesity

A cardamom and extract technology, which is applied in the field of cardamom extract and pharmaceutical preparations containing the extract, can solve the problems of separation and identification of monomers of flavonoids that have not been seen, and achieve the effect of significant therapeutic effect.

Inactive Publication Date: 2015-11-18
陈鹏
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The reported components of cardamom are mainly volatile oils, polysaccharides and proteins, and it is speculated that they also contain flavonoids, but so far no flavonoids have been isolated and identified

Method used

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  • Cardamom extract, preparation containing cardamom extract, and application of cardamom extract in treatment of obesity
  • Cardamom extract, preparation containing cardamom extract, and application of cardamom extract in treatment of obesity

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] Embodiment 1: the amount of dried tangerine peel medicinal material is 0.05 times of the weight of cardamom

[0032] Take 10kg of cardamom medicinal material and 0.5kg of tangerine peel medicinal material and mix and pulverize; extract with 75% ethanol aqueous solution under heat reflux for 3 times, extract with 50L for 3 hours for the first time, and extract with 30L for 2 hours for the second and third times; extract the obtained extract Concentrate until there is no alcohol smell, enrich with D101 macroporous resin, remove impurities with 35% ethanol, elute until the eluate is colorless, then enrich the active part with 70% ethanol, elute until the eluate is colorless , the 70% ethanol eluate was concentrated and spray-dried.

Embodiment 2

[0033] Embodiment 2: the amount of medicinal material of tangerine peel is 0.06 times of the weight of cardamom

[0034] Take 10kg of cardamom medicinal material and 0.6kg of tangerine peel medicinal material and mix and pulverize; extract with 75% ethanol aqueous solution under heat reflux for 3 times, extract with 50L for 3 hours for the first time, and extract with 30L for 2 hours for the second and third times; extract the obtained extract Concentrate until there is no alcohol smell, enrich with D101 macroporous resin, remove impurities with 35% ethanol, elute until the eluate is colorless, then enrich the active part with 70% ethanol, elute until the eluate is colorless , the 70% ethanol eluate was concentrated and spray-dried.

Embodiment 3

[0035] Embodiment 3: the medicinal material amount of tangerine peel is 0.08 times of the weight of cardamom

[0036] Take 10kg of cardamom medicinal material and 0.8kg of tangerine peel medicinal material and mix and pulverize; extract with 75% ethanol aqueous solution under heat reflux for 3 times, extract with 50L for 3 hours for the first time, and extract with 30L for 2 hours for the second and third times; extract the obtained extract Concentrate until there is no alcohol smell, enrich with D101 macroporous resin, remove impurities with 35% ethanol, elute until the eluate is colorless, then enrich the active part with 70% ethanol, elute until the eluate is colorless , the 70% ethanol eluate was concentrated and spray-dried.

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Abstract

The invention discloses a cardamom extract, a preparation containing the cardamom extract, and the application of the cardamom extract in treatment of obesity and belongs to the field of traditional Chinese medicine. The cardamom extract can be used for preparing drugs for preventing or treating obesity. By adding a small amount of pericarpium citri reticulatae to cardamom, the finally prepared extract has a remarkable obesity treating function through extraction, impurity removal and active component enrichment and has an unexpected effect compared with a product obtained by conducting extraction on cardamom alone. Based on sufficient and reasonable experiment design, extraction, impurity removal and enrichment are conducted by means of ethanol water with proper concentration, so that the cardamom extract which has a remarkable therapeutical effect is obtained. The invention further provides a proper liquid phase analysis method used for controlling the difference between different batches of extracts prepared from medicinal materials produced in different areas and batches.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine, in particular to a cardamom extract and a pharmaceutical preparation containing the extract. The cardamom extract can be used to prepare medicines for preventing or treating obesity. Background technique [0002] Cardamom is a perennial herb. Rhizome stout, brownish red. The leaves are in two rows, the blades are narrow and long-lanceolate, and the leaf sheaths are brownish-yellow pilose. Spikes emerge from the base of the stem. The inflorescence is markedly elongated, the flowers are sparsely arranged, and the corolla is white. The fruit is oblong, with tough skin and not easy to crack. The seed mass is divided into 3 petals, with 5 to 9 seeds in each petal, and the smell of the seeds is fragrant and strong. Mainly produced in Vietnam, Sri Lanka and the Malabar (Malabar) coast of southern India. Harvest when the fruit is ripe, remove the residual fruit stalk, and dry in the sun....

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9064A61P3/04G01N30/36
Inventor 张浩杰陈鹏
Owner 陈鹏
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