Drug for treating depression and preparation method thereof

A technology for depression and pharmaceutical preparations, applied in the field of medicine, can solve the problems of poor patient compliance, inability to take long-term use, obvious toxic and side effects, and achieve the effects of less toxic and side effects, correction of long-term insomnia, and stable curative effect.

Inactive Publication Date: 2015-11-18
赵 博
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The technical problem to be solved by the present invention is to provide a traditional Chinese medicine for treating depression and its preparation method. Antidepressant drugs have obvious toxic and side effects, delayed onset of effect, poor patient compliance, and cannot be taken for a long time

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] Example 1. Recipe: Cyperus 15g, Dried Ginger 15g, Gardenia 15g, Moutan Bark 20g, Chuanxiong 20g, Anemarrhena 20g, Suanzaoren 20g, Baiziren 20g, Zhigancao 6g.

[0025] Preparation method: Weigh the 9 medicinal materials of Cyperus cyperi, dried ginger, gardenia, Moutan bark, Chuanxiong, Anemarrhena, Suanzaoren, Baiziren and Zhilicorice according to the formula, mix them, and then add water to decoct for 3 times according to the total weight of the medicinal materials. times, each time for 50 minutes, filter, and combine the filtrates; the resulting filtrates are concentrated to 300 ml of decoction according to conventional methods.

[0026] Usage and dosage: take orally, 1 dose per day, divided into 3 times.

Embodiment 2

[0027] Example 2. Recipe: Rhizoma Cyperi 10g, Dried Ginger 10g, Gardenia 10g, Cortex Moutan 15g, Rhizoma Chuanxiong 15g, Anemarrhena 15g, Suanzaoren 15g, Baiziren 15g, Zhigancao 3g.

[0028] Preparation method: Weigh the 9 herbs of Rhizoma Cyperi, Dried Ginger, Gardenia, Cortex Moutan, Rhizoma Chuanxiong, Anemarrhena, Sour Date Kernel, Cypress Kernel and Zhilicorice according to the formula, mix them, and add water to decoct twice according to the total weight of the herbs. , decocted for 40 minutes each time, filtered, combined the filtrates, concentrated the filtrate under reduced pressure to an extract with a relative density of 1.25 at 50°C, cooled, added 2 times the amount of 95% ethanol and left it for 48 hours, filtered, and recovered the ethanol from the filtrate to No alcohol smell, add appropriate amount of auxiliary materials, 0.2% sodium benzoate and 1ml essence, make up with boiled water, make 1000ml, get the oral liquid of the present invention, specification: 10...

Embodiment 3

[0030] Example 3. Recipe: Rhizoma Cyperi 30g, Dried Ginger 30g, Gardenia 30g, Moutan Cortex 40g, Chuanxiong 40g, Anemarrhena 40g, Suanzaoren 40g, Baiziren 40g, Zhigancao 8g.

[0031]Preparation method: Weigh the 9 medicinal materials of Xiangfu, dried ginger, gardenia, Moutan bark, Chuanxiong, Anemarrhena, Suanzaoren, Baiziren and Zhilicorice according to the formula, mix them, add water to decoct 4 times according to 5 times the total weight of the medicinal materials , 180 minutes each time, filter, combine the filtrates, concentrate the obtained filtrate under reduced pressure to an extract with a relative density of 1.30 at 50°C, add appropriate amount of excipients, mix well, dry, add 5% magnesium stearate, mix well, and press into tablets , coated with a film coating, and made into 1000 tablets to obtain the tablet of the present invention. Specifications: Each piece weighs 0.3g.

[0032] Usage and dosage: take orally, 3 tablets at a time, 3 times a day.

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PUM

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Abstract

The invention discloses drug for treating depression and a preparation method thereof. The drug is prepared by, by weight, 10-30 parts of prepared nutgrass galingale rhizome, 10-30 parts of dried ginger, 10-30 parts of cape jasmine fruit, 15-40 parts of peony bark, 15-40 parts of szechwan lovage rhizome, 15-40 parts of anemarrhena rhizome, 15-40 parts of spina date seed, 15-40 parts of biotae semen and 3-8 parts of honey-fried licorice root. The drug is mainly used for treating mental diseases like hepatic stagnation and spleen deficiency type depression attack, anxiety attack, fear attack, insomnia and obsession, has the advantages of stable curative effect, high compliance, independence and freeness of obvious bad reaction and is small in toxic and side effect and even supportive of long-time administration.

Description

technical field [0001] The invention relates to a medicine for treating depression and a preparation method thereof, belonging to the technical field of medicine. Background technique [0002] Depression (Depressive disorder, Depression) is a disease with high prevalence, high suicide risk and increased suicide risk, and seriously endangers human health. It has become one of the most serious public health problems in the world. Due to the accelerated pace of life in modern society and strong competitive pressure, depression has become a common mental disease that seriously endangers human health, and is a major global mental problem. It is known as "the first psychological killer of human beings". Among the top ten diseases in the world, depression ranks fifth. It is estimated that by 2020, depression will become the second largest disease that affects life expectancy and increases economic burden. In addition, the suicide rate is as high as 10% to 15%, which will lead to e...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9068A61P25/24
Inventor 赵博
Owner 赵 博
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