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Injection for treating diseases of respiratory system

A technology for injections and respiratory tracts, applied in the field of pharmaceutical preparations, can solve problems such as adverse reactions and slow onset of action

Inactive Publication Date: 2015-12-23
北京神州泰洁生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] Gastrointestinal adverse reactions often occur in clinical use of oral drugs, and the onset is slow

Method used

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  • Injection for treating diseases of respiratory system
  • Injection for treating diseases of respiratory system
  • Injection for treating diseases of respiratory system

Examples

Experimental program
Comparison scheme
Effect test

Embodiment

[0013] 1. Heat the water for injection to 50-60°C, add 20g 1,8-cineole and 80g SolutolHS15 (polyethylene glycol lauryl lithium stearate), stir well, make 1000ml, depyrogenate, filter, Filling, sterilization, that is.

[0014] 2. In order to illustrate the effect of nebulized inhalation and oral administration, the effect of the same dose of this composition on the increase of mouse abdominal capillary permeability was compared.

[0015] Select healthy male mice with a body weight of 20-22g and divide them into random groups. During the experiment, the same dose of 1,8-cineole was injected into the veins and administered orally, and injected into the tail vein of the mice 1 hour after the drug. 2% Evans blue normal saline solution 0.1ml / 10g body weight, at the same time, inject 0.8% acetic acid normal saline solution 0.2ml / mouse into the abdominal cavity, decapitate the mice after 20 minutes, cut off the abdomen and wash it repeatedly with appropriate amount of normal saline, a...

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Abstract

The invention discloses an injection for treating diseases of a respiratory system. The injection is mainly prepared from 1,8-cineole. The injection is used for treating the diseases of the respiratory system such as acute and chronic faucitis, rhinitis, asthma, obstructive (spastic) bronchitis, acute and chronic bronchitis, bronchiectasis, mucoviscidosis, cysticfibrosis and chronic obstructive pneumonia. The injection has the advantages of becoming effective rapidly, being small in dosage and high in safety, and the like.

Description

Technical field [0001] The present invention belongs to the field of pharmaceutical preparation technology, involving a pharmaceutical formula containing organic ingredients, especially involving a 1,8-eucalyptus (C 10 H 18 O, EUCALYPTOL) is an injection of the main active ingredients, which is suitable for treating respiratory diseases. Background technique [0002] Respiratory diseases seriously threaten human life, especially respiratory infectious diseases are serious medical problems, accounting for 10 % of the incidence and mortality, and 75 % of antibiotic use.Respiratory infections are divided into upper respiratory tract infections and lower respiratory infections.The upper respiratory tract infection includes ordinary colds, viral pharyngitis, laryngitis, herpes pharyngitis, pharynginine, bacterial pharyngeal-tonsillitis, etc.; Lower respiratory tract infections include acute bronchitis, bronchitis, chronic bronchitis, pneumonia, bronchial, bronchial pneumoniaExpansion,...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/08A61K31/35A61P11/00A61P11/04A61P11/02A61P11/06A61P11/14
Inventor 刘冬梅
Owner 北京神州泰洁生物科技有限公司
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