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Application of traditional Chinese medicine extract in preparation of medicine for treating chronic abacterial prostatitis

A non-bacterial, prostatitis technology, applied in the field of traditional Chinese medicine, can solve problems such as side effects and patient pain, and achieve the effect of promoting repair and reducing the degree of inflammatory response

Inactive Publication Date: 2016-03-23
QINGDAO HUAZHICAO PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, antibiotics and analgesics are often used in clinical treatment, but antibiotics and analgesics have certain side effects, and the treatment process is very painful for patients

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0016] The preparation of embodiment 1 granule

[0017] Ingredients: Nansha ginseng 1.2kg, white mustard seed 1.2kg, stone melon seeds 2.0kg, sea cassia 1.4kg, evening primrose 2.5kg, chrysanthemum round leaves 2.5kg, golden gentian 1.2kg, willow leaves 0.8kg.

[0018] Preparation: Weigh and clean the above-mentioned Chinese medicinal materials according to the prescription amount, combine them, crush them, add water to decoct twice, add water for the first time to 10 times the weight of the medicinal materials, decoct for 2 hours, add water for the second time to be 8 times the weight of the medicinal materials amount, decoct for 1 hour, combine the decoction, concentrate under reduced pressure at 0.07MPa and 65°C to an extract with a relative density of 1.15, add 95% (v / v) ethanol to make the alcohol content reach 75% (v / v) , stirred, stood still for 24 hours, filtered, the filtrate was concentrated under reduced pressure at 0.07MPa and 65°C to a relative density of 1.25, an...

Embodiment 2

[0019] The preparation of embodiment 2 granules

[0020] Ingredients: Nansha ginseng 1.5kg, white mustard seed 1.2kg, stone melon seed 1.8kg, sea cassia 1.8kg, evening primrose 2.0kg, mountain elixir round leaves 3.0kg, golden gentian 1.0kg, willow leaves 1.0kg.

[0021] Preparation: Weigh the cleaned and cleaned raw materials of the above Chinese medicinal materials according to the prescription, combine them, crush them, add water to decoct twice, add water for the first time to 10 times the weight of the medicinal materials, decoct for 2 hours, and add water for the second time to 8 times the weight of the medicinal materials. Double the amount, decoct for 1 hour, combine the decoctions, concentrate under reduced pressure at 0.07MPa and 65°C to an extract with a relative density of 1.15, add 95% (v / v) ethanol to make the alcohol content reach 75% (v / v) , stirred, stood still for 24 hours, filtered, the filtrate was concentrated under reduced pressure at 0.07MPa and 65°C to ...

Embodiment 3

[0022] Experimental Study on the Curative Effect of Example 3 Traditional Chinese Medicine Granules on Chronic Nonbacterial Prostatitis Rat Model

[0023] 60 2-month-old female SD rats, with an initial body weight of 210-250g, were free to eat and drink, and kept light and dark alternately for 12 hours. The indoor temperature was 18-25°C, the humidity was 45%-65%, and the ventilation was good. Adapt to the environment for 1 week. Rats were divided into model control group, treatment group and sham operation group with 20 rats by random number table method. After the rats were anesthetized by intraperitoneal injection of 10% chloral hydrate, a median incision was made in the lower abdomen under aseptic conditions to expose the seminal vesicles and prostate on both sides. Rats were injected with 0.2 mL of 25% Xiaozhiling injection into the lateral lobe of the prostate respectively, and the abdomen was closed. After 5 weeks, the chronic non-bacterial prostatitis model can be fo...

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Abstract

The invention discloses a method for preparing traditional Chinese medicine composition granules used for treating prostatitis, and relates to the technical field of traditional Chinese medicine. The traditional Chinese medicine composition granules are prepared by taking radix adenophorae, semen brassicae, dischidia chinensis Champ. ex Benth., black fovea snails, oenothera biennis, folium turpiniae, conyza blinii and willow leaves as raw materials. According to the prepared traditional Chinese medicine composition granules, by lowering the level of TNF-alpha and IL-8 in the prostate tissue of a patient, the treating effect on the chronic abacterial prostatitis is achieved, the inflammation reaction degree is reduced, and then repairing of the prostate tissue structure is promoted.

Description

[0001] This application is an invention patent application submitted by the applicant Shandong Weikang Biomedical Technology Co., Ltd. (the name of the invention is: a traditional Chinese medicine composition for the treatment of prostatitis and its application, the application number is: 2014104612187, and the application date is: September 2014 12) divisional application. technical field [0002] The invention belongs to the technical field of traditional Chinese medicine, and relates to the application of a traditional Chinese medicine extract in preparing a medicine for treating prostatitis. Background technique [0003] Chronic nonbacterial prostatitis is a common male urological disease, mainly manifested as pain in the pelvic region, which can be found in the perineum, penis, perianal region, urethra, pubic region, and lumbosacral region. Abnormal urination can be manifested as urgency, frequency, dysuria, and nocturia. Due to chronic pain that cannot be cured for a ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/76A61P13/08A61K35/618
CPCA61K9/1652A61K35/618A61K36/11A61K36/185A61K36/27A61K36/28A61K36/31A61K36/342A61K36/76A61K2236/15A61K2236/331A61K2236/39A61K2236/51A61K2236/53A61K2236/55A61K2300/00
Inventor 王宪成
Owner QINGDAO HUAZHICAO PHARMA CO LTD
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