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Traditional Chinese medicine composition for treating prostatitis and application thereof

A technology of prostatitis and composition, applied in the field of traditional Chinese medicine, can solve the problems of patients' pain and side effects, achieve the effect of reducing the degree of inflammatory response and promoting repair

Inactive Publication Date: 2014-12-03
山东卫康生物医药科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, antibiotics and analgesics are often used in clinical treatment, but antibiotics and analgesics have certain side effects, and the treatment process is very painful for patients

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0015] The preparation of embodiment 1 granule

[0016] Ingredients: Nansha ginseng 1.2kg, white mustard seed 1.2kg, stone melon seeds 2.0kg, sea cassia 1.4kg, evening primrose 2.5kg, chrysanthemum round leaves 2.5kg, golden gentian 1.2kg, willow leaves 0.8kg.

[0017] Preparation: Weigh and clean the above-mentioned Chinese medicinal materials according to the prescription amount, combine them, crush them, add water to decoct twice, add water for the first time to 10 times the weight of the medicinal materials, decoct for 2 hours, add water for the second time to be 8 times the weight of the medicinal materials amount, decoct for 1 hour, combine the decoction, concentrate under reduced pressure at 0.07MPa and 65°C to an extract with a relative density of 1.15, add 95% (v / v) ethanol to make the alcohol content reach 75% (v / v) , stirred, stood still for 24 hours, filtered, the filtrate was concentrated under reduced pressure at 0.07MPa and 65°C to a relative density of 1.25, an...

Embodiment 2

[0018] The preparation of embodiment 2 granules

[0019] Ingredients: Nansha ginseng 1.5kg, white mustard seed 1.2kg, stone melon seed 1.8kg, sea cassia 1.8kg, evening primrose 2.0kg, mountain elixir round leaves 3.0kg, golden gentian 1.0kg, willow leaves 1.0kg.

[0020] Preparation: Weigh the cleaned and cleaned raw materials of the above Chinese medicinal materials according to the prescription, combine them, crush them, add water to decoct twice, add water for the first time to 10 times the weight of the medicinal materials, decoct for 2 hours, and add water for the second time to 8 times the weight of the medicinal materials. Double the amount, decoct for 1 hour, combine the decoctions, concentrate under reduced pressure at 0.07MPa and 65°C to an extract with a relative density of 1.15, add 95% (v / v) ethanol to make the alcohol content reach 75% (v / v) , stirred, stood still for 24 hours, filtered, the filtrate was concentrated under reduced pressure at 0.07MPa and 65°C to ...

Embodiment 3

[0021] Example 3 Experimental Study on the Curative Effect of Chinese Medicine Granules on Chronic Nonbacterial Prostatitis Rat Model

[0022] 60 2-month-old female SD rats, with an initial body weight of 210-250g, were free to eat and drink, and kept light and dark alternately for 12 hours. The indoor temperature was 18-25°C, the humidity was 45%-65%, and the ventilation was good. Adapt to the environment for 1 week. Rats were divided into model control group, treatment group and sham operation group with 20 rats by random number table method. After the rats were anesthetized by intraperitoneal injection of 10% chloral hydrate, a median incision was made in the lower abdomen under aseptic conditions to expose the seminal vesicles and prostate on both sides. Rats were injected with 0.2 mL of 25% Xiaozhiling injection into the lateral lobe of the prostate respectively, and the abdomen was closed. After 5 weeks, the chronic non-bacterial prostatitis model can be formed. The p...

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Abstract

The invention discloses a traditional Chinese medicine composition for treating prostatitis and an application thereof. The traditional Chinese medicine composition comprises a traditional Chinese medicine extract and pharmaceutic adjuvants, wherein the traditional Chinese medicine extract is prepared from the following raw materials in parts by weight: 9-15 parts of adenophora tetraphylla, 9-15 parts of semen brassicae, 17-24 parts of Chinese pholidota herb, 10-18 parts of haliotidis concha, 20-30 parts of evening primrose, 20-30 parts of folium turpiniae, 9-15 parts of conyza blinii and 6-10 parts of salix leaf, by means of water extract and alcohol precipitate. The therapeutic action on chronic abacterial prostatitis is achieved by reducing TNF-alpha and IL-8 levels in the prostate tissue of a patient, and the inflammatory reaction degree is reduced; therefore, restoration of a prostate tissue structure is promoted.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine, and in particular relates to a traditional Chinese medicine composition for treating prostatitis and its application. Background technique [0002] Chronic nonbacterial prostatitis is a common male urological disease, mainly manifested as pain in the pelvic region, which can be found in the perineum, penis, perianal region, urethra, pubic region, and lumbosacral region. Abnormal urination can be manifested as urgency, frequency, dysuria, and nocturia. Due to chronic pain that cannot be cured for a long time, the quality of life of patients is reduced, and they may have symptoms of sexual dysfunction, anxiety, depression, insomnia, and memory loss. At present, antibiotics and analgesics are used clinically for treatment, but antibiotics and analgesics have certain side effects, and the treatment process is very painful for patients. [0003] Traditional Chinese medicine has ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/76A61P13/08A61K35/56
CPCA61K9/1652A61K35/618A61K36/11A61K36/185A61K36/27A61K36/28A61K36/31A61K36/342A61K36/76A61K2236/15A61K2236/331A61K2236/39A61K2236/51A61K2236/53A61K2236/55A61K2300/00
Inventor 王宪成
Owner 山东卫康生物医药科技有限公司
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