A high-throughput micro-hybrid chip based on alternating current electrothermal and its application

Abstract

The invention discloses a high flux micro mixed chip based on alternating current heat, a preparation method and applications thereof, and relates to a micro mixed chip, a preparation method and applications thereof. The invention aims to solve the problems that a certain deviation is generated in a micro mixer when the conductivity of solution is too large; and the fluids in the whole channel height cannot be evenly mixed. Chip: the surface of the glass substrate is provided with four sets of three dimensional electrodes and ITO electrode lead; the lower surface of PDMS cover sheet is provided with a particle reaction runner, two ends of the particle reaction runner are provided with three sets of runners; the first runner and second runner are both provided with an inlet groove, the third runner is provided with an outlet through hole; the glass substrate and lower surface of PDMS cover sheet are relatively sealed, one end of the four sets of three dimensional electrodes is attached on two sides of the particle reaction runner, and the other end is attached on the ITO electrode lead. Method: a PDMS channel is processed at first, then a three dimensional electrode is processed, and finally the chip is prepared. Application: particles are prepared in advanced, and then experiment is performed.

Description

technical field [0001] The invention relates to micro-hybrid chips and applications. Background technique [0002] Microfluidic chip refers to the integration or basic integration of the basic operation units involved in the fields of biology and chemistry, such as sample preparation, reaction, separation, detection, etc., into a chip of several square centimeters (or even smaller). , forming a network of microchannels and automatically completing the whole process of analysis, it has developed into a very promising research field with interdisciplinary (mechanical, chemical, biological, medical, fluid mechanics, etc.), and it has great potential in the rapid detection of diseases Advantage. Or in the process of rapid and accurate detection of viruses or bacteria, how to quickly and efficiently mix fluids is of great significance for biological and chemical analysis on microfluidic chips. [0003] There are several methods for mixing microfluidics, including active and pas...

AI Technical Summary

Problems solved by technology

[0004] The invention aims to solve the problem that the existing micro-mixer will produce a certain deviation when the conductivity of the solution is too large, and mainly uses a planar electrode, which cannot well mix the fluid on the entire channel height well, and provides a High-throughput micro-hybrid chip based on alternating current electrothermal and its preparation method and application

Images