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Preparation method of Folium Rubi Suavissimi and Radix Isatidis mixed original tea

A technology of isatis root and sweet tea, applied in medical preparations containing active ingredients, tea substitutes, drug combinations, etc., can solve problems such as target limitation, inability to effectively prevent and treat diabetes complications, and improve lipid metabolism abnormalities and kidney damage. Effect

Inactive Publication Date: 2016-05-11
桂林双象生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Although the prior art discloses that sweet tea can be used alone to treat diabetes, its targets are relatively limited and cannot effectively prevent the occurrence of diabetic complications

Method used

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  • Preparation method of Folium Rubi Suavissimi and Radix Isatidis mixed original tea
  • Preparation method of Folium Rubi Suavissimi and Radix Isatidis mixed original tea

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0013] Mix and pulverize sweet tea leaves and Radix Radix at a weight ratio of 1:1, add 60v% ethanol, the amount of ethanol added is 4 times the total weight of Sweet Tea and Radix Radix, extract for 1 hour under ultrasonic conditions with a temperature of 40°C and a frequency of 250Hz, Add lime water to the extract to adjust the pH to 7.6, centrifuge, filter off the supernatant, and freeze-dry the precipitate, which is the composite original tea.

Embodiment 2

[0019] Mix and pulverize sweet tea leaves and Radix Radix at a weight ratio of 1:10, add 75v% ethanol, the amount of ethanol added is 10 times the total weight of sweet tea and Radix Radix, extract 3 times under ultrasonic conditions with a temperature of 50°C and a frequency of 400Hz, Combine the extracts for 2 hours each time, add lime water to the extracts to adjust the pH to 7.8, centrifuge, filter the supernatant, and freeze-dry the precipitate to obtain the compound original tea.

Embodiment 3

[0021] Mix and pulverize sweet tea leaves and Radix isatidis according to a weight ratio of 2:1, add 70v% ethanol, the amount of ethanol added is 6 times the total weight of sweet tea and Radix isatidis, and extract twice under ultrasonic conditions with a temperature of 45°C and a frequency of 300Hz. Combine the extracts for 1.5 hours each time, add lime water to the extracts to adjust the pH to 7.8, centrifuge, filter off the supernatant, and freeze-dry the precipitate to obtain the compound original tea.

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Abstract

The invention discloses a preparation method of Folium Rubi Suavissimi and Radix Isatidis mixed original tea, comprising the steps: mixing Folium Rubi Suavissimi and Radix Isatidis according to a weight ratio of 1-2:1-10, adding 60-75 v% of ethyl alcohol, extracting under ultrasonic wave, adding lime water into extract to adjust pH to 7.6-7.8, centrifuging, filtering to remove supernate, and freeze-drying precipitate to obtain the mixed original tea. The mixed original tea made by the invention is synergistic in terms of blood glucose reduction for diabetes and has certain protective action for improving diabetic complication metabolic disorder and kidney injury.

Description

technical field [0001] The invention relates to a preparation method of a composite raw tea, in particular to a preparation method of a composite raw tea of ​​sweet tea and Radix isatidis. Background technique [0002] Diabetes is a chronic life-long disease. With the improvement of people's living standards, its incidence is increasing year by year. In order to control blood sugar, long-term sugar-restricted diet and drug treatment also seriously affect the quality of life of patients. Sweet tea (Rubus Suavissmus S Lee) is the leaf of a natural sweet plant unique to Guangxi, and it is also the best sweet plant in the world with high sweetness, low heat, safety, non-toxicity and health care function. Sweet tea contains about 4.1% bioflavonoids, 18.04% sweet tea polyphenols and 5% Rubusoside. Studies have found that rubusoside can reduce the blood sugar level of normal mice, and has obvious inhibitory effect on gluconeogenesis in mice. Streptozotocin-induced hyperglycemia ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/315A61P3/10A61P3/06A61P13/12A23F3/34
CPCA61K36/185A23F3/34A61K9/0095A61K36/315A61K2236/333A61K2236/51A61K2236/53A61K2300/00
Inventor 杨丹程忠泉温宇吴丽文孙显屏徐宝敏
Owner 桂林双象生物科技有限公司
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