The application of traditional Chinese medicine composition

A composition and technology of traditional Chinese medicine, applied in the field of application of traditional Chinese medicine composition, can solve the problems of unsuitable fast pace, good compliance, complicated compatibility, complicated processing methods, etc.

Inactive Publication Date: 2017-01-04
JIANGSU KANION PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0005] However, some of the above-mentioned traditional Chinese medicine prescriptions have complicated compatibility, and som

Method used

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  • The application of traditional Chinese medicine composition
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  • The application of traditional Chinese medicine composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] The preparation of embodiment 1 Chinese medicine composition

[0026] Take 20kg of Rhizoma Chuanxiong and 10kg of Gastrodia elata, dry them, crush them, mix them, and then extract them with 90% ethanol under reflux, combine the extracts, filter, and concentrate the filtrate to the first clear ointment with a specific density of 1.27 at 55-65°C; Decocting, combining the decoction, filtering, and concentrating the filtrate to the second clear paste with a specific density of 1.27 at 55-65°C; combining with the above-mentioned first clear paste and second clear paste, adding drug-acceptable excipients, vacuum drying, pulverizing, sieve.

Embodiment 2

[0027] The preparation of embodiment 2 Chinese medicine composition

[0028] Take 50kg of Rhizoma Chuanxiong and 10kg of Gastrodia elata, dry them, crush them, mix them, and then extract them with 90% ethanol under reflux, combine the extracts, filter, and concentrate the filtrate to the first clear ointment with a specific density of 1.27 at 55-65°C; Decocting, combining the decoction, filtering, and concentrating the filtrate to the second clear paste with a specific density of 1.27 at 55-65°C; combining with the above-mentioned first clear paste and second clear paste, adding drug-acceptable excipients, vacuum drying, pulverizing, sieve.

Embodiment 3

[0029] The preparation of embodiment 3 Chinese medicine composition

[0030] Take 35kg of Rhizoma Chuanxiong and 10kg of Gastrodia elata, dry them, crush them, mix them, and then extract them with 90% ethanol under reflux, combine the extracts, filter, and concentrate the filtrate to the first clear ointment with a specific density of 1.27 at 55-65°C; Decocting, combining the decoction, filtering, and concentrating the filtrate to the second clear paste with a specific density of 1.27 at 55-65°C; combining with the above-mentioned first clear paste and second clear paste, adding drug-acceptable excipients, vacuum drying, pulverizing, sieve.

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Abstract

This invention relates to the field of traditional Chinese medicine, particularly to the application of traditional Chinese medicine composition. The invention provides the application of a traditional Chinese medicine composition comprising Sichuan lovage rhizome and tall gastrodia tuber in the traditional Chinese medicine preparation for increasing the content of serotonin, norepinephrine and dopamine in the brain. This invention also provides the application of the traditional Chinese medicine composition comprising Sichuan lovage rhizome and tall gastrodia tuber in the manufacture of a medicament for the treatment and / or prophylaxis of depression. The experimental results of the invention show that the provided composition can significantly reduce the immobility time in the mice forcing swimming and the tail suspension experiment, and increase the amount of serotonin (5-HT), norepinephrine (NE), Dopamine (DA), whose effect is similar to the positive control drug paroxetine, suggesting that the compositions provided by the present invention will play an important role in the treatment or prevention of depression.

Description

[0001] This application claims the priority of the Chinese patent application submitted to the China Patent Office on August 25, 2016, with the application number 201610730515.6 and the title of the invention "Use of Traditional Chinese Medicine Composition", the entire content of which is incorporated in this application by reference. technical field [0002] The invention relates to the field of traditional Chinese medicines, in particular to the application of traditional Chinese medicine compositions. Background technique [0003] Depression is caused by various reasons. It is a group of mood disorders or affective disorders with depression as the main symptom. It is a clinical syndrome or state centered on self-experience of depressed mood. Its main manifestations are depressed mood, decreased speech, mental , slow movement, severe cases and even attempted suicide. According to the statistics of the World Health Organization, depression affects more than 150,000 people ...

Claims

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Application Information

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IPC IPC(8): A61K36/8988A61P25/24
CPCA61K36/8988A61K36/236A61K2300/00
Inventor 萧伟孙晓萍周军常秀娟赵静孙永城李贵平王振中胡晗绯
Owner JIANGSU KANION PHARMA CO LTD
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