External pharmaceutical composition

Abstract

To provide a pharmaceutical technique which inhibits yellowing caused under temporal or high temperature conditions, while containing diclofenac and/or a salt thereof and tocopherol and/or a derivative thereof, in an external pharmaceutical composition which contains water, to enable having an excellent storage stability. In an external pharmaceutical composition containing diclofenac and/or a salt thereof, tocopherol and/or a derivative thereof, and water, containing lactic acid and/or a salt thereof can inhibit yellowing caused under temporal or high temperature conditions to enable having an excellent storage stability.

Description

technical field [0001] The present invention relates to an external pharmaceutical composition containing diclofenac and / or a salt thereof, tocopherol and / or a derivative thereof, and water, which suppresses yellowing over time or under high temperature conditions and has excellent storage stability. Background technique [0002] In modern society, the number of people suffering from shoulder pain, muscle pain, joint pain, etc. has increased due to the same posture for a long time, excessive stress, and lack of exercise due to the spread of OA equipment. Conventionally, for such shoulder pain, muscle and joint pain, etc., anti-inflammatory analgesics have been applied in order to suppress inflammation in the affected area and improve symptoms. [0003] Conventionally, non-steroidal anti-inflammatory drugs such as diclofenac, felbinac, dexamethasone, indomethacin, and ibuprofen have been put into practical use as anti-inflammatory analgesics. Among these non-steroidal anti-i...

AI Technical Summary

Problems solved by technology

When diclofenac is administered orally or rectally, gastrointestinal, renal, or hepatic damage may occur as a side effect, and

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