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Electrochemical detecting system

A detection system and electrochemical technology, applied in medical science, diagnostic recording/measurement, sensors, etc., can solve the problems of limited diffusion speed of dialysis membranes, inability to use neurotransmitter vesicle release event on-line detection, etc., to achieve long-term solution The effect of time-continuous detection

Active Publication Date: 2017-02-22
INST OF ELECTRONICS CHINESE ACAD OF SCI
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Problems solved by technology

However, due to the limitation of the diffusion rate of the dialysis membrane, the time resolution of microdialysis detection and analysis is on the order of minutes, which cannot be used for online detection of neurotransmitter vesicle release events on the order of milliseconds.

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  • Electrochemical detecting system
  • Electrochemical detecting system
  • Electrochemical detecting system

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Embodiment Construction

[0027] In order to make the object, technical solution and advantages of the present invention clearer, the present invention will be further described in detail below in conjunction with specific embodiments and with reference to the accompanying drawings.

[0028] It should be noted that, in the drawings or descriptions of the specification, similar or identical parts all use the same figure numbers. And in the drawings, the embodiments are marked for simplification or convenience. Furthermore, elements or implementations not shown or described in the drawings are forms known to those of ordinary skill in the art. Additionally, while illustrations of parameters comprising particular values ​​may be provided herein, the parameters need not be exactly equal to the corresponding values, but rather may approximate the corresponding values ​​within acceptable error margins or design constraints.

[0029] In an exemplary embodiment of the present invention, an electrochemical det...

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Abstract

The invention discloses an electrochemical detecting system, which comprises self-reference microelectrode arrays including a plurality of detection sties positioned at the parts to be detected. Reference signals and electrochemical response signals can be acquired simultaneously at the same detection site. An electrochemical surveymeter connected with the self-reference microelectrode arrays is to detect concentrations of chemical substance variation of a plurality of detection sties and output data. The electrochemical detecting system can resolve the problem of consecutively detecting rapid release of cerebral trace neurotransmitters for yonks for researches of neuroscience, and provide a novel research tool and means for researches of neuroscience.

Description

technical field [0001] The invention relates to the field of signal detection in the electrochemical industry, in particular to an electrochemical detection system. Background technique [0002] Neurotransmitter is a kind of specific chemical substance that produces signal transduction between chemical synapses of neurons. After it is synthesized in neurons, it is released from the presynaptic membrane and immediately binds to the corresponding postsynaptic membrane receptors to Complete the function of neural information transmission. Neurotransmitters are closely related to human health, and play an important role in the regulation of physiological functions such as learning, memory, neuronal plasticity, body movement, and brain development. Therefore, it is of great significance to carry out research on the release of neurotransmitters in the brain in vivo to understand the mechanism of brain operation, study the etiology of brain diseases, drug treatment, and clinical b...

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Application Information

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IPC IPC(8): A61B5/00A61B5/05
CPCA61B5/05A61B5/4064A61B5/6847A61B5/6868A61B5/7203A61B5/7225A61B5/725A61B2503/40A61B2503/42
Inventor 徐声伟蔡新霞刘军涛王蜜霞宋轶琳罗金平徐辉任肖桂花张松
Owner INST OF ELECTRONICS CHINESE ACAD OF SCI
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