54 results about "Neuroscience research" patented technology

Apparatus for applying Transcranial Magnetic Stimulation (TMS) to a patient, the apparatus including a head mount for disposition on the head of a patient; and a plurality of magnet assemblies for releasable mounting on the head mount, wherein each of the magnet assemblies includes a magnet for selectively providing a rapidly changing magnetic field capable of inducing weak electric currents in the brain of a patient so as to modify the natural electrical activity of the brain of the patient; wherein the number of magnet assemblies mounted on the head mount, their individual positioning on the head mount, and their selective provision of a rapidly changing magnetic field is selected so as to allow the spatial, strength and temporal characteristics of the magnetic field to be custom tailored for each patient, whereby to provide patient-specific TMS therapy, to assist in diagnosis or to map out brain function in neuroscience research.

Apparatus for applying Transcranial Magnetic Stimulation (TMS) to an individual, wherein the apparatus comprises: a head mount for disposition on the head of an individual; and a plurality of magnet assemblies for releasable mounting on the head mount, wherein each of the magnet assemblies comprises a permanent magnet, and at least one of (i) a movement mechanism for moving the permanent magnet and / or (ii) a magnetic shield shutter mechanism, for selectively providing a rapidly changing magnetic field capable of inducing weak electric currents in the brain of an individual so as to modify the natural electrical activity of the brain of the individual; wherein the number of magnet assemblies mounted on the head mount, their individual positioning on the head mount, and their selective provision of a rapidly changing magnetic field is selected so as to allow the spatial, strength and temporal characteristics of the magnetic field to be custom tailored for each individual, whereby to provide individual-specific TMS therapy, to assist in diagnosis or to map out brain function in neuroscience research.

The invention discloses a method for eliminating myoelectricity noise in an electroencephalogram signal based on a single channel. The method is characterized by comprising the steps that firstly, a single-channel electroencephalogram signal is decomposed into a plurality of intrinsic mode components through general average empirical mode decomposition; secondly, blind signal separation s conducted on the intrinsic mode components through multi-set canonical correlation analysis, and a plurality of canonical variables are obtained; finally, the canonical variables with the autocorrelation coefficient lower than a certain threshold value are judged to be myoelectricity noise, the myoelectricity noise variables are removed, and reconstruction is conducted to obtain the electroencephalogram signal with the myoelectricity noise removed. According to the method, the purpose of eliminating the myoelectricity noise in the electroencephalogram signal is effectively achieved from the brand new angle of the single channel, and compared with the traditional blind signal separation technology based on the multiple channels, the myoelectricity noise can be better eliminated. The method is suitable for portable and wearable single-channel and few-channel electroencephalogram devices, is also suitable for multi-channel electroencephalogram devices for clinical diagnosis and neuroscience researches, and significant importance is achieved in further researches of the true physiological activities of the human brain.

The invention belongs to the field of cell biology and relates to a method and reagent for the separation and culture of neurons. The method and the reagent are used for solving problems in the prior art, the current in-vitro hippocampal neuron separation and culture methods are improved, and the problem that the proliferation and activity of hippocampal neurons during primary culture can not be maintained is solved. According to the method and the reagent, a relatively mature in-vitro hippocampal neuron culture method is established, the number of obtained nerve cells is sufficient, the growth status is relatively good, and a large number of high-activity hippocampal nerve cells can be separated from mammalian hippocampal tissue, so that the requirements for the primary culture of the hippocampal cells are met, and the demands on experiments of cell biology during neuroscience research can be met.

The invention discloses a visualization method and device for long-range projection neurons. The method comprises the following steps: splitting an artificially tracked neuron skeleton tree to obtaina plurality of sub-segment fibers; extracting a neighborhood three-dimensional image signal of the sub-segment fiber and projecting the neighborhood three-dimensional image signal; and combining the projection images of the sub-segment fibers to obtain a complete image signal of the neurons. The device comprises a first acquisition module used for acquiring a projection image of neuron sub-segmentfibers based on an artificially tracked neuron skeleton tree; and a second acquisition module which is used for combining all the neuron sub-segment fiber projection images to obtain neuron completeimage signals. According to the method, complete image information of a single neuron can be quickly extracted according to the whole cranial nerve element morphological data set and the artificiallytracked neuron skeleton file, so that a neuroscience researcher can quickly visualize original image data of the whole neuron conveniently.