Brain function experimental task stimulation system with real-time feedback and task update functions

A technology for experimental tasks and real-time feedback, applied in image data processing, telemetry patient monitoring, health index calculation, etc., can solve problems such as low efficiency, achieve effective and rapid positioning, improve scanning efficiency, and shorten the total time

Active Publication Date: 2017-08-15
ZHEJIANG UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

The present invention can not only detect and analyze the activation level of the brain in real time, but also guide the business process of subs...

Method used

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  • Brain function experimental task stimulation system with real-time feedback and task update functions
  • Brain function experimental task stimulation system with real-time feedback and task update functions
  • Brain function experimental task stimulation system with real-time feedback and task update functions

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0061] Example 1: Example of quick positioning of functional areas

[0062] In one of the examples of rapid positioning of functional areas, taking the finger-moving experimental task of block design as an example, it is illustrated that when the whole-brain activation statistical parameter map is fed back to the experimenter as the task response level of the subject, the experimenter One-click trigger to manipulate the direction of the business process to quickly locate the steps of the primary motor cortex.

[0063] In one example of rapid positioning of the functional area, 12s was allowed for the T1 signal to stabilize at the beginning of the experiment, and then 30s of finger-moving and gaze-stimulating materials were alternately presented using block design.

[0064] In one embodiment of the fast positioning of functional areas, because the activation statistics parameter map of the whole brain is used as the task response level of the subject, the target brain area posi...

Embodiment 2

[0073] Embodiment 2: Two-stage task function activity scanning task update embodiment

[0074] In one of the two-stage task update examples, taking the two-stage task experiment of moving the right hand and moving the left hand as an example, it shows that in one scan, the brain function stimulator evaluates the subject's performance in different stages according to the preset threshold conditions. The task response situation is used to intelligently control the direction of the experimental business process, so as to realize the step process of seamless switching between different task stages.

[0075]In one instance of a two-stage task update, the experiment initially allowed 12 s for the T1 signal to stabilize. When moving the right hand in the first stage of the task, the block-designed movement of the right hand and the gaze state stimulus material appeared alternately for 30s; when the left hand was moved in the second stage of the task, the block-designed movement of th...

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Abstract

The present invention discloses a brain function experimental task stimulation system with real-time feedback and task update functions. The system comprises a computing platform, for detecting and positioning a brain functional area in real time, monitoring image quality of brain function imaging in real time, and detecting and feed backing the current task response level of the brain; the computing platform is provided with a target brain area positioning module, a data quality monitoring module, a task level detection module and a feedback module; the computing platform is also provided with a data acquisition and real-time transmission module, wherein the original function magnetic resonance image is transmitted to the computing platform after acquisition and reconstruction by using a magnetic resonance scanner; and the computing platform is further provided with a task update module, for presenting new experimental task material by comparing and determining to trigger and control the brain function stimulator. According to the system disclosed by the present invention, efficiency of the statistical determination on the active level of the specific brain area is improved, the total time of brain function signal acquisition is shortened, and the system has great practical significance to improve the scanning efficiency of brain function activity and fast positioning of the functional area in clinical patients, and can be applied to the neurological research related to brain functional area detection.

Description

technical field [0001] The invention relates to a brain function experiment task stimulation system with real-time feedback and task update functions, specifically refers to the real-time detection of the current task response level by collecting and analyzing brain functional magnetic resonance images in real time, and according to the current brain interest The judgment and feedback of the active status of the area guide the subsequent changes in experimental task materials, thereby optimizing the functional task experimental business process and shortening the total time of fMRI scans. Background technique [0002] Functional Magnetic Resonance Imaging (fMRI) uses magnetic resonance imaging to measure hemodynamic changes caused by neuronal activation. When neurons in a certain tissue or functional area of ​​the brain are activated, it is manifested as blood flow in that area. increase. Due to its noninvasiveness to the human body and excellent spatiotemporal resolution, ...

Claims

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Application Information

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IPC IPC(8): G06F19/00G06T7/00A61B5/00A61B5/055
CPCA61B5/0042A61B5/055A61B2576/026G06T7/0012G06T2207/10088G06T2207/30016G16H50/20G16H50/30
Inventor 何宏建韩璐丁秋萍窦权钟健晖
Owner ZHEJIANG UNIV
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