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55 results about "Neuronal activation" patented technology

Neural activations are mostly stimulated circularly. A neuron is activated by other neurons to which it is connected. In turn, its own activation stimulates other connected neurons to activation. If an impulse is started at any one place on the axon, it propagates in both directions.

Accurate positioning method of rehabilitation FES signal for stroke patients

The invention relates to the fields of biomedical engineering, computer technology and communication, and specifically discloses an accurate positioning method of a rehabilitation FES signal for stroke patients. The method comprises the steps of wearing a dynamic exoskeleton, defining sensor parameters, performing healthy joint movement, recording exercise data of a healthy joint and the myoelectric signal data of adjacent limbs, and calculating the corresponding motion data of an affected joint and the action time and action point of the FES. The accurate positioning method determines a functional electrical stimulation site and a timing of the affected joint through the healthy joint motion of the patients, instead of determining by the experience of a rehabilitation engineer, by using the principle of time-lapse mirroring, each patient can find electrical stimulation time and action positions suitable for own physical conditions, the FES stimulation on the patients makes the actionof the patient affected joint closer to the action of normal limbs, which can better improve the activation of the brain mirror neurons and promote the rehabilitation of the patients, and the method can help the stroke patients to correct gait during the rehabilitation process to a certain extent.
Owner:深圳睿瀚医疗科技有限公司

Parameter regulation method and device for neuron activation function

The invention discloses a parameter regulation method and device for a Noisy Softplug neuron activation function. The method comprises the following steps that: setting a parameter to be set as an initial value, and using an activation function which finishes parameter setting for an artificial neural network so as to obtain the highest pattern recognition accuracy rA of the artificial neural network; in a preset LIF (Leaky Integrate-and-Fire) neuron, selecting a noise value [Sigma]0, adopting a least square method to carry out fitting on a corresponding relationship between constant current with different sizes and [Sigma]0 and a pulse spike rate, and determining the value of each parameter to be set; on the basis of the above determined value, updating an initial value, and regulating the activation function; on the basis of the regulated activation function, training the artificial neural network, applying a weight obtained by training to a pulse neural network to obtain the highestpattern recognition accuracy rB of the pulse neural network; and if rA-rB is smaller than a set value, finishing regulating parameters, and otherwise, reselecting [Sigma]0. By use of the method, theartificial neural network can be guaranteed to be trained to obtain the weight suitable for the pulse neural network, and therefore, the pattern recognition accuracy of the pulse neural network is improved.
Owner:GUANGDONG UNIV OF TECH

Fast memory coding method and device based on multi-synaptic plasticity spiking neural network

The invention provides a fast memory coding method based on a multi-synaptic plasticity pulse neural network. The fast memory coding method comprises the steps of 1, converting external stimulation into an input pulse sequence based on a hierarchical coding strategy; 2, after the pulse neural network receives an input pulse, updating a membrane potential of neurons of an output layer based on an improved SRM model; 3, updating a synaptic weight input to an output layer by using a supervisory group Tempotron, and activating neuron memory input of the output layer; step 4, after the neurons of the output layer are activated, using the unsupervised STDP to update synaptic weights among the activated neurons in the layer, and forming an enhanced cyclic sub-network storage memory; and step 5, while executing the step 4, using unsupervised inhibition synaptic plasticity, updating a synaptic weight between an inhibition layer and an output layer, and inhibiting separation of distribution time of neural populations with different inputs of feedback guarantee memories. The invention further provides a fast memory coding device based on the multi-synaptic plastic spiking neural network. According to the invention, the coding speed and stability of memory are effectively improved.
Owner:ZHEJIANG LAB +1

Federal learning security aggregation method and apparatus, and electronic device

The invention provides a federated learning security aggregation method and device and electronic equipment. The method comprises the following steps: acquiring model parameter update information of all users participating in federated learning for a current sample category; according to the model parameter updating information, performing model parameter updating on a preset global model to obtain a new global model corresponding to each user; extracting a test sample corresponding to the current sample category from a preset test set, and inputting the test sample into the new global model to obtain a neuron average activation value corresponding to each new global model; determining a user clustering result according to the neuron average activation value corresponding to each new global model; and according to a user clustering result, determining malicious users currently participating in federal learning. The malicious user is determined according to the model neuron activation conditions of different users for a certain sample category, so that the authentication of the federated learning participating user identity is realized, and the reliability of a federated learning aggregation result is improved.
Owner:国网智能电网研究院有限公司南京分公司 +4

Peripherally restricted FAAH inhibitors

ActiveUS9187413B2Enhancing peripheral activityBiocideNervous disorderDepressantPharmaceutical medicine
Peripherally restricted inhibitors of fatty acid amide hydrolase (FAAH) are provided. The compounds can suppress FAAH activity and increases anandamide levels outside the central nervous system (CNS). Despite their relative inability to access brain and spinal cord, the compounds attenuate behavioral responses indicative of persistent pain in rodent models of inflammation and peripheral nerve injury, and suppresses noxious stimulus-evoked neuronal activation in spinal cord regions implicated in nociceptive processing. CBi receptor blockade prevents these effects. Accordingly, the invention also provides methods, and pharmaceutical compositions for treating conditions in which the inhibition of peripheral FAAH would be of benefit. The compounds of the invention are according to the formula (I): in which R1 is a polar group. In some embodiments, R1 is selected from the group consisting of hydroxy and the physiologically hydro lysable esters thereof. R2 and R3 are independently selected from the group consisting of hydrogen and substituted or unsubstituted hydrocarbyl; each R4 is independently selected from the group consisting of halogen and substituted or unsubstituted hydrocarbyl and n is an integer from 0 to 4; each R5 is independently selected from the group consisting of halo and substituted or unsubstituted hydrocarbyl and m is an integer from 0 to 3; and R6 is substituted or unsubstituted cyclohexyl; and the pharmaceutically acceptable salts thereof.
Owner:UNIV DEGLI STUDI DI URBINO +1

Peripherally restricted faah inhibitors

ActiveUS20130217764A1Enhancing peripheral activityBiocideNervous disorderBehavioral responseReceptor blockade
Peripherally restricted inhibitors of fatty acid amide hydrolase (FAAH) are provided. The compounds can suppress FAAH activity and increases anandamide levels outside the central nervous system (CNS). Despite their relative inability to access brain and spinal cord, the compounds attenuate behavioral responses indicative of persistent pain in rodent models of inflammation and peripheral nerve injury, and suppresses noxious stimulus-evoked neuronal activation in spinal cord regions implicated in nociceptive processing. CBi receptor blockade prevents these effects. Accordingly, the invention also provides methods, and pharmaceutical compositions for treating conditions in which the inhibition of peripheral FAAH would be of benefit. The compounds of the invention are according to the formula (I): in which R1 is a polar group. In some embodiments, R1 is selected from the group consisting of hydroxy and the physiologically hydro lysable esters thereof. R2 and R3 are independently selected from the group consisting of hydrogen and substituted or unsubstituted hydrocarbyl; each R4 is independently selected from the group consisting of halogen and substituted or unsubstituted hydrocarbyl and n is an integer from 0 to 4; each R5 is independently selected from the group consisting of halo and substituted or unsubstituted hydrocarbyl and m is an integer from 0 to 3; and R6 is substituted or unsubstituted cyclohexyl; and the pharmaceutically acceptable salts thereof.
Owner:UNIV DEGLI STUDI DI URBINO +1

Longitudinal federated learning backdoor defense method based on neuron activation value clustering

The invention discloses a longitudinal federated learning backdoor defense method based on neuron activation value clustering. The method comprises the following steps: constructing a longitudinal federated recommendation system comprising a plurality of participants and collaborators; and federated learning: after obtaining a constructed commodity guiding link corresponding to the aggregation embedding representation, the collaboration party classifies the commodity guiding link to effectively screen out a commodity guiding link with potential backdoor attack, and repairs the commodity guiding link with the backdoor attack by using a clustering result. The back door attack commodity sample is guided to learn towards a correct prediction direction, so that the commodity sample of a participant does not need to be obtained, and the repaired commodity recommendation model can defend the back door attack; and the joint embedded representation with the same ID as the aggregation embedded representation of the backdoor attack is filtered or attacked and repaired, so that the parameter optimization of the aggregation embedded representation of the backdoor attack on the commodity recommendation model is prevented or improved, and the defense capability of the commodity recommendation model on the backdoor attack is improved.
Owner:浙江君同智能科技有限责任公司
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