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Implanted intracranial administration intubate suitable for neuroscience research

A neuroscience and implantable technology, applied in medical science, catheters, pharmaceutical devices, etc., can solve the problems of stability, fixed airtightness, poor operability and accuracy, and achieve good airtightness and low price , cheap effect

Inactive Publication Date: 2007-01-10
INST OF PSYCHOLOGY CHINESE ACADEMY OF SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The purpose of the present invention is to solve the problems of poor stability, fixity, airtightness, operability and accuracy of the above-mentioned existing self-made intracranial intubation materials, thereby providing a medical stainless steel with stable physical and chemical properties. Implantable intracranial cannula made of materials, with a sealed structure and a stable structure, used in brain drug cannula for brain science research

Method used

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  • Implanted intracranial administration intubate suitable for neuroscience research
  • Implanted intracranial administration intubate suitable for neuroscience research
  • Implanted intracranial administration intubate suitable for neuroscience research

Examples

Experimental program
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Embodiment 2

[0038] refer to Figure 2a -c, making a pair of intracranial drug delivery catheters made of implantable medical polyurethane materials for rabbits and cats. The size of the core and other components is different, and the specific data can be within the following range:

[0039] The outer diameter of the cannula is 0.7-3.0mm; the inner diameter of the cannula is 0.6-2.8mm;

[0040] The thickness of the fixed base is 1.0-2.0mm; the diameter of the fixed base is 8.0mm-15.0mm;

[0041] The length of the extracranial end of the cannula is 2.0mm to 5.0mm; the length of the external thread is 2.0mm to 5.0mm;

[0042] The outer diameter of the extracranial end of the intubation tube is 3.2mm to 4.0mm; the outer wall has external threads, which can be screwed with the internal threads on the inner wall of the sealing cap;

[0043] The intracranial length of the cannula is 2.0mm to 80.0mm (the intracranial length can be determined according to the needs of the experiment); the total...

Embodiment 3

[0050] refer to Figure 2a -c, make an implantable stainless steel intracranial drug cannula for dogs and monkeys used in experiments, its structure is the same as in Example 1, except for the size of the cannula and fixed base, sealing cap and cannula filling inner core Not the same, the specific data are as follows:

[0051] The outer diameter of the cannula is 1.6mm; the inner diameter of the cannula is 1.4mm;

[0052] The thickness of the fixed base is 1.5mm; the diameter of the fixed base is 20.0mm;

[0053] The length of the extracranial end of the cannula is 3.5mm; the length of the external thread is 3.5mm;

[0054] The outer diameter of the extracranial end of the cannula is 5.5mm, and the intracranial length of the cannula is 4.0-100.0mm (the intracranial length can be determined according to the needs of the experiment);

[0055] The total length of the cannula was 7.5-103.5 mm.

[0056] The outer diameter of the sealing cap is 6.5mm; the inner diameter of the s...

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Abstract

This invention relates to an interpolation encephalic medicine-feeding canula for nerve scientific research including an integral structure canula and a fixed base, an integral structural airproof cap and a canula filling core, in which, said base is a staged revolving body and screw thread is lathed on the outer wall of a tube part of the staged revolving body, said sealing cap and the core are like a capsule, a rod extending from the inside of the top of the capsule and screwed on the fixed base is set in the inside wall of the capsule as the filling core of the canula to form an integral structure and the outside diameter of the core is a bit smaller than that of the internal diameter, the length of the core is the same with that of the canula and medical stainless steel or polyurethane are materials of the components.

Description

technical field [0001] The invention relates to an intracranial cannula for neuroscience research, in particular to an implantable intracerebral cannula which can be used for intracerebral drug delivery in neuroscience research. Background technique [0002] Many neuroscience research fields need to use the method of intracerebral administration or administration of certain biological agents to explore some physiological and pathological phenomena or the mechanism of certain diseases. This method is one of the basic methods widely used and of great significance since the development of neurobiology. Medical scientists and neurobiologists use this method to increase or decrease the excitability of nerve cells in a certain part of the brain through intracranial intubation, or to damage a certain target brain area by injecting neurotoxic excitatory amino acids through intubation. Or neural nuclei, inferring the new functions of these unknown brain regions or known brain region...

Claims

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Application Information

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IPC IPC(8): A61M39/00A61M25/00A61M37/00A61M31/00A61F2/02A61B17/00
Inventor 郑瑞茂隋南翁旭初祝世功薛林
Owner INST OF PSYCHOLOGY CHINESE ACADEMY OF SCI
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