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Composition comprising extract of alpine wormwood

A technology of composition and extract, which is applied in the field of compositions containing Artemisia alpina extract, can solve problems such as damage to skin homeostasis, weaken skin moisturizing and barrier function, and reduce immune activity, so as to maintain the anti-stress effect and maintain Skin homeostasis, the effect of reducing the amount of EDN1

Inactive Publication Date: 2017-02-22
AMOREPACIFIC CORP
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Reduced immune activity induced by stress may lead to disruption of skin homeostasis, which in turn can impair skin moisturizing and barrier functions that protect the skin from harmful external factors

Method used

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  • Composition comprising extract of alpine wormwood
  • Composition comprising extract of alpine wormwood
  • Composition comprising extract of alpine wormwood

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0082] [Example 1] Preparation of Artemisia umbelliformis extract

[0083] The flowers of Alpine Artemisia are harvested, dried with hot air and crushed into powder. The obtained powder was extracted with ethanol / water solution, and then the ethanol was removed by vacuum distillation. After adding glycerin and a preservative to the resulting concentrate, Alpine Artemisia was obtained by filtration. From DSM Nutritional Products Ltd. (4002Basel, Switzerland) to buy the Artemisia alpina extract prepared according to the above method ( Artemisa AO), used in the following test examples.

Embodiment 2

[0110] [Dosage Form Example 2] Tablet

[0111] 8 mg of the Artemisia alba extract of Example 1, 9 mg of vitamin E, 9 mg of vitamin C, 200 mg of galacto-oligosaccharides, 60 mg of lactose and 140 mg of maltose were mixed and a fluidized bed dryer was used. Then, after adding 6 mg of sugar ester, the mixture was prepared into tablets containing 500 mg of the composition according to the usual method.

Embodiment 3

[0112] [Dosage Form Example 3] Drink

[0113] Mix 8 mg of Artemisia alba extract of Example 1, 9 mg of vitamin E, 9 mg of vitamin C, 10 g of glucose, 0.6 g of citric acid and 25 g of oligosaccharide syrup, and add 300 mL of purified water. 200 mL of the mixture was filled into bottles. Then, the drink was prepared by sterilizing at 130° C. for 4-5 seconds.

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PUM

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Abstract

Disclosed is a composition containing an extract of alpine wormwood (Artemisia Umbelliformis) as an active ingredient. The composition disclosed in the present specification has the effect of reducing the amount of endothelin 1 and reducing the overexpression of NK1R and EDN1 genes due to the composition containing the extract of an alpine wormwood (Artemisia Umbelliformis). Accordingly, due to such effects, the alpine wormwood (Artemisia Umbelliformis) extract of the present specification can exhibit benefits for maintaining skin homeostasis and an anti-stress effect, and thus can be widely used in the pharmaceutical or cosmetics fields as a composition for maintaining skin homeostasis.

Description

technical field [0001] The present invention relates to compositions comprising Artemisia alpina extract. Background technique [0002] Stress, known as the cause of all modern diseases, refers to: when a certain degree or higher degree of stimulation (regardless of the type of stimulation) acts on the body in a harmful way and poses a threat to the body, Nonspecific general adaptation syndrome as a response to this threat (Selye, H.: The stress of life, Toronto, LongnansGreen and Co., pp. 1-50, 1958). The causes of stress mainly include (1) physical factors: overwork, lack of sleep, trauma, poisoning, etc.; (2) external factors: natural environment, cultural situation, interpersonal relationships in the family or workplace, etc.; and (3) internal factors : Personality, psychological conflicts in life, trauma experienced by an infant or child, etc. [0003] When the stress lasts for a long time, it may cause physical diseases such as heart disease, gastric ulcer and high b...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/282A61K8/9789A61P17/00A61Q19/00
CPCA61K36/282A61K2800/782A61K2800/92A61Q19/00A61K8/9789A61P17/00A61P17/16A61P43/00A23V2002/00A23V2200/318A23V2200/322A23V2300/14A61K2236/33A23L33/105A61P25/00A23L2/52A61K9/0095A61K9/20A61K9/48A23L33/15A23L33/155A23L33/16
Inventor 朴泌俊李昭希曹恩敬李泰龙
Owner AMOREPACIFIC CORP
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