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Chinese brain language area distribution graph construction method

A construction method and distribution map technology, applied in the field of medical image processing and application, to achieve the effect of large individual differences, perfect reference and guidance

Inactive Publication Date: 2017-03-08
AFFILIATED HUSN HOSPITAL OF FUDAN UNIV
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  • Application Information

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Problems solved by technology

Based on the similarities and differences between English and Chinese language processing in functional magnetic resonance imaging research, the inventors of the present application aim at the current situation that there is no recognized Chinese language brain language area in the prior art, and propose that there should be a language distribution map based on ISM On the basis of similarities and differences, a method for constructing the distribution map of Chinese brain language regions is provided

Method used

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  • Chinese brain language area distribution graph construction method
  • Chinese brain language area distribution graph construction method
  • Chinese brain language area distribution graph construction method

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Effect test

Embodiment 1

[0030] Embodiment 1 builds the distribution map of Chinese brain language area

[0031] The construction method of the Chinese brain language area distribution map in this embodiment mainly includes the construction of a two-dimensional probability map, a three-dimensional surface distribution map, and a statistical parameter map based on a random effect model. Distribution; which includes:

[0032] Constructing a two-dimensional probability map: Based on the Ch2 template and then generating a grid map, the template is divided into 234 squares. By referring to intraoperative images and neuronavigation, two neurosurgeons (JF Lu, JS Wu) The location of the direct electrical stimulation (ISM) in the center is marked on the grid map; then the positive probability in each square is calculated; in addition, the positive probability in all the squares is up-sampled by the method of the difference of the cube, and the pseudo-color map displayed in the form of

[0033] A three-dimens...

Embodiment 2

[0044] Example 2 Accurate positioning of the Chinese brain language area clinical experiment

[0045] Cases were selected based on the following inclusion criteria: 1) Han adults; 2) daily Mandarin speaking; 3) right-handed; 4) according to preoperative structural and functional magnetic resonance imaging, the lesion was located in the language area of ​​the left hemisphere of the brain; 5) preoperative Intracranial tumors considered; exclusion criteria: 1) severe speech impairment or cognitive impairment; 2) intraoperative neurophysiological monitoring or contraindications for wake-up surgery (i.e. patients with obstructive sleep apnea syndrome or severe intracranial hypertension) ; 3) The initial diagnosis was extracranial tumor; 4) The mass effect caused obvious brain deformation; a total of 55 patients from 8 different provinces in China were included in the study; from December 2010 to December 2012, 55 patients A case of left glioma underwent language function localizati...

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Abstract

The invention relates to the field of medical image processing and application, in particular to a Chinese brain language area distribution graph construction method. The invention provides a new group-based reliable Chinese language distribution graph construction method for a current situation of locating of a Chinese brain language area not universally accepted yet in the prior art. According to the method, a Chinese brain language area distribution graph is constructed based on intraoperative cortical electrical stimulation and can be applied to the neurosurgery to accurately locate the Chinese brain language area. The construction method mainly comprises the steps of constructing a two-dimensional probability graph, a three-dimensional surface distribution graph, and a random effect model-based statistic parameter graph; and displaying the distribution situation of the language function area in the brain from two-dimensional and three-dimensional perspectives. According to the method, the deviation caused by operation of locating the Chinese language function area only by MRI can be effectively avoided; the Chinese language area can be accurately located through intraoperative language locating; and better reference and guidance are provided for clinical surgeries.

Description

technical field [0001] The invention relates to the field of medical image processing and application, in particular to a method for constructing a distribution map of brain functional areas, and in particular to a method for constructing a distribution map of Chinese brain language areas. The method constructs a distribution map of Chinese brain language areas based on intraoperative cortical electrical stimulation. It can be used in neurosurgery to accurately locate the language area of ​​the Chinese brain. Background technique [0002] Relevant research practices have shown that Chinese is different from English and other alphabetic languages. Alphabet languages ​​use letters as elements to form a linear structure, while Chinese characters are a non-linear structure composed of pictographs. English reading follows the rules of phonetic-sound conversion, that is, each letter can correspond to the smallest unit of pronunciation, while reading Chinese characters requires th...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G06F19/00
Inventor 吴劲松路俊锋章捷于政达毛颖周良辅
Owner AFFILIATED HUSN HOSPITAL OF FUDAN UNIV
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