Drug for treating cirrhosis with ascites, preparation method thereof and application

A cirrhotic ascites and drug technology, applied in the field of medicine, can solve the problems of slow curative effect of traditional Chinese medicine, long-term use, water and electrolyte disorders, etc., achieve quick results, improve liver function, and relieve pain

Inactive Publication Date: 2017-05-10
郑州莉迪亚医药科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Western medicine eliminates ascites quickly, focusing on improving liver function, using diuretics to increase the excretion of water and sodium, and promoting the reso...

Method used

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  • Drug for treating cirrhosis with ascites, preparation method thereof and application
  • Drug for treating cirrhosis with ascites, preparation method thereof and application
  • Drug for treating cirrhosis with ascites, preparation method thereof and application

Examples

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Comparison scheme
Effect test

Embodiment 1

[0016] In an embodiment of the present invention, a medicine for treating liver cirrhosis ascites is composed of the following raw materials in parts by weight: 7 parts of catechin, 1 part of benzbromarone, 11 parts of chitin, and 3 parts of usnic acid.

[0017] Mix and grind benzbromarone and chitin, pass through a 120-mesh sieve, add deionized water 3.7 times the mass of the two, then raise the temperature to 81°C, and stir at this temperature for 36 minutes to prepare mixture A. Put usnic acid and catechin into the mixture A, then ultrasonically treat at 56°C for 28min with an ultrasonic power of 1000W, then stir at 61°C until dry, and granulate to obtain the drug.

Embodiment 2

[0019] In an embodiment of the present invention, a medicine for treating liver cirrhosis ascites is composed of the following raw materials in parts by weight: 15 parts of catechin, 5 parts of benzbromarone, 19 parts of chitin, and 7 parts of usnic acid.

[0020] Mix and grind benzbromarone and chitin, pass through a 120-mesh sieve, add deionized water 3.7 times the mass of the two, then raise the temperature to 83°C, and stir at this temperature for 39 minutes to prepare mixture A. Put usnic acid and catechin into the mixture A, then ultrasonically treat at 56°C for 28min with an ultrasonic power of 1000W, then stir at 61°C until dry, and granulate to obtain the drug.

Embodiment 3

[0022] In an embodiment of the present invention, a medicine for treating liver cirrhosis ascites is composed of the following raw materials in parts by weight: 9 parts of catechin, 2 parts of benzbromarone, 13 parts of chitin, and 4 parts of usnic acid.

[0023] Mix and grind benzbromarone and chitin, pass through a 120-mesh sieve, add deionized water 3.7 times the mass of the two, then raise the temperature to 82°C, and stir at this temperature for 37 minutes to prepare mixture A. Put usnic acid and catechin into the mixture A, then ultrasonically treat at 56°C for 28min with an ultrasonic power of 1000W, then stir at 61°C until dry, and granulate to obtain the drug.

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Abstract

The invention discloses a drug for treating cirrhosis with ascites, a preparation method thereof and an application; the drug is prepared from, by weight, 7-15 parts of catechinic acid, 1-5 parts of benzbromarone, 11-19 parts of chitin, 3-7 parts of usnic acid. The drug is prepared by mixing and grinding benzbromarone and chitin; sieving through 120 meshes; adding 3.7 times of deionized water by mass of the both; then raising temperature to 81-83 DEG C, and stirring for 36-39 min under the temperature; preparing a mixture A; placing usnic acid and catechinic acid in a mixture A, then performing ultrasound treatment on the mixture for 28 min at 56 DEG C; stirring the mixture until dry at 61 DEG C, and prilling the mixture. The total effective rate for treating the cirrhosis with ascites is 98% above, and the drug can improve liver function of patients, correct hypoproteinemia and rapidly remove ascites, while reduce complication. The raw materials are simple and easy to acquire, the preparation technique is simple, the production cost is low, the treatment effect is good, and visible effect is quick; the drug is free from toxic and side effects, and applicable to large-scale production and popularization.

Description

technical field [0001] The invention relates to the technical field of medicine, in particular to a medicine for treating liver cirrhosis ascites and its preparation method and application. Background technique [0002] Liver cirrhosis is a common clinical chronic progressive liver disease, which is diffuse liver damage caused by long-term or repeated effects of one or more causes. In my country, most of them are post-hepatitis cirrhosis, and a small part are alcoholic cirrhosis and schistosome cirrhosis. Histopathologically, extensive liver cell necrosis, nodular regeneration of residual liver cells, connective tissue hyperplasia, and fibrous septum formation lead to structural destruction of hepatic lobules and formation of pseudolobules. The liver gradually deforms and hardens and develops into cirrhosis. In the early stage, there are no obvious symptoms due to the strong compensatory function of the liver. In the later stage, liver function damage and portal hypertensio...

Claims

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Application Information

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IPC IPC(8): A61K31/722A61P1/16A61P7/10A61K31/353A61K31/343
CPCA61K31/353A61K31/343A61K31/722A61K2300/00
Inventor 不公告发明人
Owner 郑州莉迪亚医药科技有限公司
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