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A kind of light-proof medical pvc infusion tube composition and preparation method thereof

An infusion tube and composition technology, applied in the field of PVC infusion tube composition, can solve the problems of narrow light shielding band, potential safety hazard, buried patient health, etc., and achieve good light shielding effect, high transparency, and the effect of improving safety and stability

Active Publication Date: 2020-04-14
CHINA PETROLEUM & CHEM CORP
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The applicant found in the research that: the existing infusion tube composition has the problem of narrow light-shielding band, which easily leads to changes in the drug properties of the infusion bag or infusion tube when storing light-proof drugs
In the prior art, due to the use of a large amount of opacifying agents, the composition with a wider light-shielding band has the problem of poor light transmission, which leads to inconvenience in observation during use.
However, when applied to infusion materials, the added light stabilizer often has the problem of precipitation and contamination of the liquid medicine, which poses a safety hazard to the health of patients.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] Embodiments 1 to 5 are specific implementations of a light-shielding medical PVC infusion tube composition and a preparation method thereof of the present invention. Wherein embodiment 1 is the best embodiment.

[0023] Table 1 Formula components of medical PVC infusion tubes in Examples 1-5 (by weight)

[0024] .

[0025] The preparation method of embodiment 1~5 adopts the following steps: polyvinyl chloride resin, thermal stabilizer, plasticizer, compound light stabilizer, titanium dioxide, lubricant are weighed by weight, put into high-speed mixer and mix 10~ After 12 minutes, when the liquid phase components are completely absorbed by the polyvinyl chloride resin, and the compounded material has no adhesion and is evenly dispersed, put it into a low-speed mixer to cool, and discharge the material after the material temperature is lower than 60°C to obtain the mixed material, that is have to.

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PUM

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Abstract

The invention provides a light-shielding type medical PVC (Polyvinyl Chloride) infusion tube composition and a preparation method of the light-shielding type medical PVC infusion tube composition and belongs to the technical field of PVC infusion tube compositions. The light-shielding type medical PVC infusion tube composition is prepared from the following raw materials in parts by weight: 100 parts of polyvinyl chloride resin, 1.0 to 3.0 parts of a thermal stabilizer, 40 to 60 parts of a plasticizer, 1.5 to 4 parts of a compound light stabilizer, 0.01 to 0.025 part of titanium dioxide and 0.1 to 0.2 part of a lubricant; the compound light stabilizer is prepared by mixing a hindered amine light stabilizer, phenyl salicytate, benzotriazoles and 4-(1-naphthylazo)-1-naphthol. The light-shielding type medical PVC infusion tube composition provided by the invention has the advantages of less light capable of penetrating through a waveband of 290nm to 450nm, high transparency and no toxin.

Description

technical field [0001] The invention belongs to the technical field of PVC transfusion tube composition, and in particular relates to a light-shielding medical PVC transfusion tube composition and a preparation method thereof. Background technique [0002] In the clinical infusion process, some drugs (such as the anti-tuberculosis drug PAS) are easy to decompose when exposed to light, resulting in a decrease in curative effect, so they need to be infused in a light-proof environment. When light drugs are infused, dark plastic containers are often temporarily used to wrap the infusion bottle and the infusion tube. However, there are still many shortcomings and deficiencies in this operation method, which is not conducive to observing the liquid level and is inconvenient to operate. The wavelength range of the light that is likely to cause drug decomposition is 290-450nm. The national standard requires that the light-proof infusion tube has a transmittance of 290-450nm band li...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): C08L27/06C08L83/04C08K13/02C08K3/22C08K5/12C08K5/23C08K5/3475C08K5/134
Inventor 张桦李静刘浩孙丽朋刘容德王晓敏王秀丽桂俊杰孙培培王海波盛梅高磊
Owner CHINA PETROLEUM & CHEM CORP
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