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Adaptive Replanning Based on Multimodal Imaging

A technique for treatment planning, imaging, and application at point will be apparent from the description that follows. It can solve the time-consuming and difficult problems of complete automation

Active Publication Date: 2021-11-26
THE MEDICAL COLLEGE OF WISCONSIN INC
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

However, challenges remain with such online replanning schemes as they require delineation of the target and OAR, which is a time-consuming and difficult process to fully automate

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  • Adaptive Replanning Based on Multimodal Imaging
  • Adaptive Replanning Based on Multimodal Imaging
  • Adaptive Replanning Based on Multimodal Imaging

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Embodiment Construction

[0041] Current clinical practice associated with the delivery of any one or more radiation therapy treatments involves complex, carefully coordinated workflows using a multitude of tools and systems designed to achieve maximum patient benefit. figure 1 An example flow chart illustrating the general steps associated with such a radiation therapy treatment process is shown. Process 100 typically begins at process block 10, where various imaging methods are typically used to generate medical image information from a patient for diagnostic or therapeutic purposes. For example, as in figure 1 As shown, this may include the use of a computed tomography (CT) device, a magnetic resonance imaging (MRI) device, a positron emission tomography (PET) imaging device, an ultrasound (US) imaging device, and the like. Information obtained from imaging is used in radiation therapy (RT) for two main purposes. First, it is used to determine the true three-dimensional position and extent of targ...

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Abstract

Systems and methods for adaptive radiation therapy planning are provided. In some aspects, provided systems and methods include generating composite images from magnetic resonance data using relaxation mapping. The method includes applying a correction to the data and generating a relaxation map therefrom. In other aspects, a method for adapting a radiation therapy plan is provided. The method involves determining an objective function based on dose gradients from an initial dose distribution, and generating an optimized plan based on updated images using aperture deformation and gradient maintenance algorithms without at-risk organ contouring. In yet other aspects, methods are provided for obtaining 4D MR imaging using temporal shuffling of data acquired during normal respiration for deformable images using a sequentially applied semi-physical model regularization method for multimodal images A method of registration, and a method for generating a 4D plan based on 4D CT or 4D MR imaging using an aperture deformation algorithm.

Description

[0001] CROSS-REFERENCE TO RELATED APPLICATIONS [0002] This application claims US Provisional Patent Application Sequence entitled "SYSTEMS AND METHODS FOR ADAPTIVEREPLANNING BASED ON MULTI-MODALITY IMAGING", filed December 31, 2013 No. 61 / 922,343 priority. Background technique [0003] The present disclosure relates generally to tools, systems, and methods for use in radiation therapy treatment delivery and, more particularly, to systems and methods for adaptive planning based on multimodality imaging. [0004] Radiation therapy (RT) has undergone a series of technological revolutions over the past few decades. With intensity-modulated RT (IMRT), it becomes possible to generate a highly conformal dose distribution, thereby delivering the majority of the radiation dose within the confines of the tumor. These techniques utilize 3D anatomical information as well as biological information extracted from images of various types (eg, CT, MRI, PET) acquired in the days prior to t...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61B5/103A61N5/10G06T11/00G06T17/00G06T7/33G06T5/00G06T5/40
CPCA61N5/1038A61N5/1037A61B5/055A61B5/7289A61B6/032A61B6/037A61B6/4417A61B6/5247A61B8/4416A61B8/483A61B8/5261G06T7/11A61N5/1039A61B5/0036G06F18/24G06T11/003G06T2207/10012G06T2207/10076G06T2207/10081G06T2207/10088
Inventor X·A·李E·S·保尔森E·阿汉贝C-g·杨V·哈特
Owner THE MEDICAL COLLEGE OF WISCONSIN INC
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