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Device and method for measuring urine sodium value of women

A measurement method, a female technology, applied in the field of medicine, can solve the problems of large deviation, cumbersome process, and inconvenience of patients in the determination of urine sodium value, and achieve the effect of simple measurement

Inactive Publication Date: 2020-07-10
刘明欣 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

24-hour urine sodium measurement is the most reliable and accurate method at present, but the 24-hour urine collection time is long and the process is cumbersome, which brings a lot of inconvenience to patients
[0013] The applicant's research team found that: 1. Use when to spot urine to estimate 24-hour urine sodium. In view of differences in race and diet, research results in different countries are inconsistent, and there is no relevant data for the Chinese population.
2. For high-salt (salt intake > 12g / day) and medium-low-salt (salt intake ≤ 12g / day) crowd, as well as people of different genders (male and female) in the medium-low-salt crowd There is a big difference in the results
However, this patent is not accurate in the calculation of the urine sodium value of the Chinese population, and there is no difference in the urinary sodium value of the high-salt and medium-low salt intake population, and the urinary sodium value of the population of different genders in the medium-low salt population. Different characteristics were not studied
The applicant's early application CN104569366A, CN104698160A provided a test kit for evaluating male 24-hour urine sodium value, CN104569437A, CN104569438A provided a test kit for evaluating female 24-hour urine sodium value, yet the test results showed The measurement deviation of urine sodium value is still large, and only distinguishes the urine sodium value of different gender groups, without taking into account the differences in the measurement of urine sodium values ​​of different sex groups with high salt intake and medium and low salt intake

Method used

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  • Device and method for measuring urine sodium value of women
  • Device and method for measuring urine sodium value of women

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Experimental program
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Effect test

Embodiment 1

[0066] Establishment of the inventive method

[0067] The data were collected from hypertensive patients hospitalized in the hypertension ward of Peking University People's Hospital from March 2013 to May 2014. Inclusion criteria: ①The diagnosis of hypertension was clear. The diagnostic criteria of hypertension were based on the 2010 Chinese guidelines for the prevention and treatment of hypertension. Hypertension was defined as systolic blood pressure ≥ 140mmHg (1mmHg = 0.133kPa) and (or) diastolic blood pressure ≥ 90mmHg when blood pressure was measured 3 times on different days without using antihypertensive drugs. The patient had a history of hypertension in the past and was currently using antihypertensive drugs. His blood pressure was <140 / 90mHg, and he was also diagnosed as hypertension. ② Stable regular diet in the past 1 month. ③ Fill in the informed consent. Exclusion criteria: ①Hypertension accompanied by severe multi-system diseases (such as rheumatic immune di...

Embodiment 2

[0085] Embodiment 2, verification of the inventive method

[0086] There were 158 female patients in the verification group. The predicted value of urine sodium (e-24HUNa) was calculated by the Tanaka method and the SUN1 method respectively. The accuracy of the predicted value and the measured value (r-24HUNa) were compared. The results are as follows: Table 1:

[0087] The applicability of the modified SUN formula was verified in a population with low and moderate salt intake (N=791).

[0088] Applicability is to assess the degree of agreement between the predicted 24-hour urine sodium of the applied formula and the measured value. In this study, the applicability of the improved SUN formula will be evaluated from the aspects of accuracy, consistency, sensitivity and specificity and compared with Kawasaki formula and Tanaka formula.

[0089] Table 2 Kawasaki formula, Tanaka formula and improved SUN formula

[0090]

[0091]

[0092] The SMU samples were brought into ...

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Abstract

The invention provides a measurement device and method for female urine sodium value among medium-and-low-sodium salt people. The device comprises a urine component quantity detection unit and a 24-hour urine sodium value calculation unit, wherein the urine component quantity detection unit is used for detecting the component quantity contained in spot urine excreted within a predetermined period of time, and the component quantity comprises spot urine sodium value and spot urine creatinine value; the 24-hour urine sodium value calculation unit is used for calculating female 24-hour urine sodium value among the medium-and-low-sodium salt people based on the component quantity of the spot urine. The device has the advantage that high-precision, time-saving, simple and convenient measurement of the female 24-hour urine sodium value can be realized.

Description

technical field [0001] The invention belongs to the field of medicine, and in particular relates to a measuring method and device for evaluating 24-hour urinary sodium value of women, especially a measuring method and device for 24-hour urinary sodium value of women among people with medium and low salt intake. Background technique [0002] The World Health Organization (WHO) 2013-2020 Global Action Plan for the Prevention and Control of Chronic Diseases proposed a general control goal for the global prevention and control of chronic non-communicable diseases in 2025, namely: cardiovascular diseases, tumors and diabetes caused by premature (<70 years old ) relative reduction in the risk of death by 25%. At the same time, the amount of salt is relatively reduced by 30%. [0003] Excessive salt intake can lead to high blood pressure, and high blood pressure is an important risk factor for coronary heart disease and stroke. According to WHO statistics, about 54% of stroke a...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): G01N33/50G01N33/70
CPCG01N33/50G01N33/70
Inventor 刘明欣贾海霞刘志荣石磊
Owner 刘明欣
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