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Traditional Chinese medicine composition with blood sugar reduction effect, application of traditional Chinese medicine composition and injection prepared from traditional Chinese medicine composition

A composition and injection technology, applied in the direction of medical preparations containing active ingredients, drug combinations, ether/acetal active ingredients, etc., can solve the difficulty of screening, the effect is not significant, and the hypoglycemic effect is not significantly improved To achieve the effect of expanding the scope of use, improving medicinal value, and lowering blood sugar

Inactive Publication Date: 2017-12-15
朗致集团江西医药有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0010] Although both paclitaxel and pinitol have hypoglycemic effects, the effect of a single component is not significant, and the hypoglycemic effect of the composition formed by mixing the two has not been significantly improved, and it can be compounded with what kind of raw materials In order to improve its hypoglycemic effect, due to the different compatibility of traditional Chinese medicine compositions, the final drug effect is not the same. Even if the raw materials with the same effect are combined with each other, it cannot be completely guaranteed that no antagonistic effect will be produced, which will weaken the hypoglycemic effect or cause other serious side effects. , so that the screening of the composition with significant hypoglycemic effect using pinitol and paclitaxel as raw materials becomes extremely difficult

Method used

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  • Traditional Chinese medicine composition with blood sugar reduction effect, application of traditional Chinese medicine composition and injection prepared from traditional Chinese medicine composition
  • Traditional Chinese medicine composition with blood sugar reduction effect, application of traditional Chinese medicine composition and injection prepared from traditional Chinese medicine composition
  • Traditional Chinese medicine composition with blood sugar reduction effect, application of traditional Chinese medicine composition and injection prepared from traditional Chinese medicine composition

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Experimental program
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Effect test

Embodiment 1

[0033] The raw materials of the composition with hypoglycemic effect in this embodiment consist of: pinitol 16g, paclitaxel 4g, total flavonol glycosides 7g, ginkgolide A 2g, ginkgolide B 0.3g and ginkgolide Ester C is 1 g.

[0034] Above-mentioned paclitaxel, flavonol glycosides, ginkgolide A, ginkgolide B, ginkgolide C are mixed with water and adjuvants to make a sterile solution with a pH value of 7.0, wherein the paclitaxel is in the aseptic The content in the bacterial solution is 0.1mg / ml.

Embodiment 2

[0036] The raw materials of the composition with hypoglycemic effect in this embodiment consist of: pinitol 24g, paclitaxel 2g, total flavonol glycosides 15g, ginkgolide A 0.7g, ginkgolide B 1g and ginkgolide Ester C was 0.4 g.

[0037] Above-mentioned paclitaxel, flavonol glycosides, ginkgolide A, ginkgolide B, ginkgolide C are mixed with water and adjuvants to make a sterile solution with a pH value of 6.0, wherein the paclitaxel is in the aseptic The content in the bacterial solution is 1.5mg / ml.

Embodiment 3

[0039] The raw materials of the composition with hypoglycemic effect in this embodiment consist of: pinitol 18g, paclitaxel 3g, total flavonol glycosides 10g, ginkgolide A 0.8g, ginkgolide B 0.4g and ginkgolide Lactone C is 0.5 g.

[0040] Above-mentioned paclitaxel, flavonol glycosides, ginkgolide A, ginkgolide B, ginkgolide C are mixed with water and adjuvants to make a sterile solution with a pH value of 7.0, wherein the paclitaxel is in the aseptic The content in the bacterial solution is 1mg / ml.

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Abstract

The invention provides a traditional Chinese medicine composition which comprises pinitol, sequoyitol, total flavonoid glycoside and bilobalides A, B and C in specific parts by weight. The total flavonoid glycoside and the bilobalides A, B and C without a blood sugar reduction effect are matched with the pinitol and the sequoyitol; the effect of reducing the blood sugar of the pinitol and the sequoyitol is improved; and the composition has the significant blood sugar reduction effect.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine compositions, in particular to a traditional Chinese medicine composition with hypoglycemic effect, a preparation method and application of the composition. Background technique [0002] The sugar in the blood of the human body is called blood sugar, which mainly comes from the grains, fruits and vegetables ingested by the human body. The above-mentioned foods are converted into simple sugars (such as glucose, etc.) through the digestive system and enter the blood, and are transported to the cells of the whole body as a source of energy. If it cannot be consumed for a while, it will be converted into glycogen and stored in the liver and muscles. The liver can store 70-120 grams of sugar, accounting for about 6-10% of the liver's weight. The glycogen that cells can store is limited. If you consume too much sugar, the excess sugar will be converted into fat. Normal people have a fasting ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/16A61K9/08A61P3/10A23L2/38A23L33/10A23L33/105A23G3/36A23G3/48A21D13/06A21D2/36A61K31/075A61K31/365
CPCA21D2/36A21D13/06A23G3/36A23G3/48A23L2/38A23L33/10A23L33/105A61K9/0019A61K9/08A61K31/075A61K31/365A61K36/16A23V2002/00A61K2236/333A61K2236/51A61K2236/53A61K2236/55A61K2236/39A61K2300/00A23V2200/328A23V2250/2122
Inventor 王锋杨满辉
Owner 朗致集团江西医药有限公司
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