Four-coil structure for transcranial magnetic stimulation and application thereof

Abstract

The invention discloses a four-coil structure for transcranial magnetic stimulation and an application thereof and belongs to the transcranial magnetic stimulation field. The four-coil structure comprises four adjacent small coils in a square structure, two energy storage capacitors and 12 relays, wherein positive and negative leading wires are independently led out by each small coil, a positive electrode leading-out wire of each energy storage capacitor is connected with a silicon controlled rectifier as a discharging switch, and the two energy storage capacitors are used for controlling different relays or relay combinations for supplying power for different small coils or small coil combinations. The four-coil structure is advantaged in that magnetic stimulation focuses of multiple portions of a human brain can be simultaneously stimulated, and complex magnetic stimulation demands are satisfied.

Description

technical field [0001] The invention belongs to the field of transcranial magnetic stimulation, in particular to a four-coil structure for transcranial magnetic stimulation and a method for controlling the focus of magnetic stimulation realized by using the structure. Background technique [0002] At present, the existing transcranial magnetic stimulation at home and abroad mainly uses circular coils and "8"-shaped coils for stimulation. It is the center of the "8" character, and the area of ​​action at the center of the "8" is usually called the "magnetic stimulation focus", so the "8" shape coil has better focus than the circular coil. In the clinical research of transcranial magnetic stimulation, it was found that the physiological activities of the human brain are completed by multiple regions of the cerebral cortex. Therefore, in clinical applications, magnetic stimulation for the treatment of certain brain function diseases requires multiple regions. Stimulation, just...

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Problems solved by technology

[0004] At present, there is a lack of practical multi-focal transcranial magnetic stimulation coil structures in this field. There are several reasons for this: first, the transient current in the magnetic stimulation coil is very high, and the peak current even reaches more than 5000 amperes. flow, so the cross section of the coil wire should not be too thin, nor should it be too thick. If it is too thick, it is difficult to wind. Generally, the coil wire is preferably 6-12 square millimeters; second, the pulse magnetic field of the magnetic stimulation coil should generally be able to reach 1.5 Tesla. Above, the induced electric field must be able to reach more than 60V / m, so it is necessary to select appropriate coil parameters. If the size of the coil is too small, it cannot meet the physiological threshold requirements; and the surface area of ​​the head is limited, and the number of coils arranged will not be many, so it is not suitable. Third, due to the high transient current, the focus gating control circuit of the coil is more complicated

The patent (Application No. 201220171951.1) proposes a dynamically variable multi-channel transcranial magnetic stimulation coil array, which uses a grid of straight wires as the magnetic stimulation coil. The inductance of such a coil is too small to generate a pulsed magnetic field that meets the physiological threshold stimulation intensity. and induced electric field

The patent (application number 200510015749.4) discloses a multiconductor brain magnetic stimulator with 128 stimulation coils, each of which is a cylindrical coil with a diameter of 20 mm and a height of 20 mm. The coil is wound by 0.58 mm enameled wire with 324 turns. , the size of the coil is too small, the inductance is too large, and the current rise rate is not enough, so it cannot generate a high enough pulse magnetic field and induced electric field; in addition, the wire is too thin to carry a large transient current

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