Autologous epidermal melanin transplantation cell water survival method for treating vitiligo

Abstract

The invention discloses a method for using vitiligo autologous epidermal melanin transplantation cells to divide and activate water, comprising the following steps: using a skin puncher to take a small amount of scalp containing hair follicles from the patient's head, separating and culturing the melanocytes in the hair follicles in vitro; The cultivation, cryopreservation and recovery of melanocytes; the cultivation and expansion of melanocytes; the biological identification of the morphology and function of melanocytes and the stability of genetic traits. In the present invention, a large number of autologous melanocytes are obtained by obtaining melanocytes in autologous scalp hair follicles, cultured and expanded in vitro, and these melanocytes have normal skin melanocyte functions and can normally produce skin melanin. The lack of melanocytes in the skin lesions, so as to achieve the purpose of treating vitiligo. This treatment method is different from the traditional treatment method, autologous cells will not appear rejection, and it does not need to be treated with drugs, and there is no potential risk.

Description

technical field [0001] The invention relates to a method for using autologous hair follicle melanin to transplant cell moisture into the living method. Background technique [0002] Vitiligo is a common acquired depigmentation skin disease with complex pathogenesis. About 1% to 2% of the population in the world is suffering from vitiligo. Although there are many treatments for this disease at present, the curative effect is not satisfactory. At present, the more effective therapy is autologous melanocyte transplantation. Since the obtained melanocytes are derived from the autologous body, it will not cause rejection. Melanocytes are taken from the skin, but they face defects such as limited number, difficult separation, complicated culture process, and difficult promotion. Although there are indeed some methods for quickly separating cells on the market, because the source of the cells requires a large amount of skin, the transplanted cells are not easy to fix, survive, an...

AI Technical Summary

Problems solved by technology

About 1% to 2% of the world's population is suffering from vitiligo. Although there are many treatment methods for this disease, the curative effect is not satisfactory.

At present, the more effective therapy is autologous melanocyte transplantation. Since the obtained melanocytes are derived from the autologous body, it will not cause rejection. Melanocytes are taken from the skin, but they are limited in number, difficult to separate, complicated to cultivate, and not easy to promote.

Although there are indeed some methods for quickly separating cells on the market, because the source of the cells requires a large amount of skin, the transplanted cells are not easy to fix, survive, and distribute unevenly. There are still some disadvantages