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Pharmaceutical composition for treating dysmenorrhea, and preparation method thereof

A kind of composition and technology of medicine, applied in the field of pharmaceutical composition for treating dysmenorrhea and preparation thereof

Inactive Publication Date: 2018-03-06
CHANGCHUN UNIV OF CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although mifepristone can significantly improve the clinical symptoms of patients with adenomyosis, its side effects are inevitable

Method used

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  • Pharmaceutical composition for treating dysmenorrhea, and preparation method thereof
  • Pharmaceutical composition for treating dysmenorrhea, and preparation method thereof
  • Pharmaceutical composition for treating dysmenorrhea, and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0066] It is made from the following raw materials in parts by weight:

[0067] 10 parts of Sanleng, 10 parts of Curcuma, 10 parts of Moutan Cortex, 7 parts of Cinnamon, 20 parts of Corydalis Corydalis, 10 parts of Wuyao, 10 parts of Liu Jinu, 10 parts of Angelica, 20 parts of Paeoniae Alba, 20 parts of Rehmannia glutinosa, 20 parts of Cyperus part, 10 parts of peach kernel, 0.5 part of centipede;

[0068] For the above thirteen flavors, Corydalis Corydalis is crushed into fine powder; Sanleng, Curcuma, Moutan Cortex, Cinnamon, Angelica, and Xianggui are added with appropriate amount of water to extract volatile oil, encapsulated with beta-cyclodextrin, and set aside; medicinal dregs, Wuyao, Liu Jinu , Radix Paeoniae Alba, Rehmannia glutinosa, peach kernels, and centipede are decocted twice with 7 times the amount of water, each time for 2 hours, and the decoctions are combined, and the volatile oil extracts such as the above-mentioned triangular edges are added, filtered, and...

Embodiment 2

[0069] The preparation of embodiment 2 tablet of the present invention

[0070] 15 parts of Sanleng, 15 parts of Curcuma, 15 parts of Moutan Cortex, 10 parts of Cinnamon, 25 parts of Corydalis Corydalis, 15 parts of Wuyao, 15 parts of Liu Jinu, 15 parts of Angelica, 25 parts of Paeoniae Alba, 25 parts of Rehmannia glutinosa, 25 parts of Cyperus 15 parts of peach kernel, 1 part of centipede;

[0071]For the above thirteen flavors, Corydalis Corydalis is crushed into fine powder; Sanleng, Curcuma, Moutan Cortex, Cinnamon, Angelica, and Xianggui are added with appropriate amount of water to extract volatile oil, encapsulated with beta-cyclodextrin, and set aside; medicinal dregs, Wuyao, Liu Jinu , Radix Paeoniae Alba, Rehmannia glutinosa, peach kernel, and centipede were decocted with 8 times the amount of water for 3 times, 1.5 hours each time, combined the decoction, added the above-mentioned volatile oil extracts such as triangular, filtered, and the relative density was measu...

Embodiment 3

[0073] It is made from the following raw materials in parts by weight:

[0074] 20 parts of Sanleng, 20 parts of curcuma, 20 parts of peony bark, 13 parts of cinnamon, 30 parts of Yanhusuo, 20 parts of black medicine, 20 parts of Liu Jinu, 20 parts of angelica, 30 parts of white peony root, 30 parts of Rehmannia glutinosa, and 30 parts of Cyperus cypress 20 parts of peach kernel, 1.5 parts of centipede;

[0075] For the above thirteen flavors, Corydalis Corydalis is crushed into fine powder; Sanleng, Curcuma, Moutan Cortex, Cinnamon, Angelica, and Xianggui are added with appropriate amount of water to extract volatile oil, encapsulated with beta-cyclodextrin, and set aside; medicinal dregs, Wuyao, Liu Jinu , Radix Paeoniae Alba, Rehmannia glutinosa, peach kernel, and centipede were decocted with 9 times the amount of water for 3 times, each time for 1 hour, combined the decoction, added the above-mentioned volatile oil extracts such as triangular, filtered, and the relative de...

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Abstract

The invention relates to a pharmaceutical composition for treating dysmenorrhea, and a preparation method thereof, belonging to the field of traditional Chinese medicines. The pharmaceutical composition comprises the following raw materials in parts by weight: 10-20 parts of rhizoma sparganii, 10-20 parts of rhizoma curcumae, 10-20 parts of cortex moutan radicis, 7-13 parts of cortex cinnamomi, 20-30 parts of rhizoma corydalis, 10-20 parts of radix linderae, 10-20 parts of artemisia anomala, 10-20 parts of radix angelicae sinensis, 20-30 parts of radix paeoniae alba, 20-30 parts of radix rehmanniae preparata, 20-30 parts of rhizoma cyperi, 10-20 parts of semen persicae, and 0.5-1.5 parts of scolopendra. The pharmaceutical composition can warm channels and expel cold, remove blood stasis and relieve pain, is used for qi-stagnation and blood stasis type adenomyosis dysmenorrhea, has the advantages of low cost, high efficacy, safety and reliability in the aspect of treating dysmenorrhea,thus being worthy of further popularization and use clinically.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine, in particular to a pharmaceutical composition for treating dysmenorrhea and a preparation method thereof. Background technique [0002] Adenomyosis refers to a benign disease of the uterine body in which the glands and stroma of the endometrium diffuse and infiltrate at the base layer. Clinically, it can lead to progressively aggravated dysmenorrhea, excessive menstrual flow, and increased uniformity of the uterine body. a range of symptoms. In clinical practice, most of the patients are women of childbearing age, and it is difficult to accept surgical treatment. However, the etiology and pathogenesis of this disease are still unclear, so there is no feasible conservative treatment plan clinically. Western medicine mostly uses progesterone drugs or gonadotropin-releasing analogues to treat this disease. After stopping the drugs, the disease relapses and the adverse reactions are large...

Claims

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Application Information

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IPC IPC(8): A61K36/9066A61K47/69A61P15/00A61P29/00A61K35/648
CPCA61K36/902A61K35/648A61K36/232A61K36/282A61K36/54A61K36/65A61K36/66A61K36/71A61K36/736A61K36/804A61K36/8905A61K36/9066A61K2236/331A61K2236/39A61K2236/51A61K2236/53A61K2300/00
Inventor 王慧于秀华何宗梅李晓曦申丽媛崔明华初洪波李长慧李庆杰陈立怀潘文秀刘博
Owner CHANGCHUN UNIV OF CHINESE MEDICINE
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