Temporo-mandibular joint biological condyle constructed based on tissue engineering related technology

A technology of temporomandibular joint and related technologies, applied in tissue regeneration, coating, medical science, etc., to reduce complications, improve quality of life, and improve joint symptoms

Active Publication Date: 2018-04-13
SHANGHAI NINTH PEOPLES HOSPITAL SHANGHAI JIAO TONG UNIV SCHOOL OF MEDICINE
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In addition, it also has the advantages of reducing surgical trauma, facilitating intraoperative use, reducing the amount of osteotomy and bone grinding, and avoiding the risk of skull base injury and massive bleeding to overcome the shortcomings of current artificial joint replacement and costal cartilage transplantation.

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  • Temporo-mandibular joint biological condyle constructed based on tissue engineering related technology
  • Temporo-mandibular joint biological condyle constructed based on tissue engineering related technology
  • Temporo-mandibular joint biological condyle constructed based on tissue engineering related technology

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[0020] In order to make the object, technical solution and advantages of the present invention clearer, the present invention will be further described in detail below in combination with specific embodiments and with reference to the accompanying drawings. It should be understood that these descriptions are exemplary only, and are not intended to limit the scope of the present invention. Also, in the following description, descriptions of well-known structures and techniques are omitted to avoid unnecessarily obscuring the concept of the present invention.

[0021] The invention is mainly used in the reconstruction treatment of temporomandibular joint condyle in cases of temporomandibular joint ankylosis, late condylar osteoarthritis and various advanced condylar degeneration. Preoperative measurements were made based on the patient's panoramic film and head anterior view, and the three-dimensional model of the condyle was reconstructed based on the patient's CT data, so as t...

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Abstract

The invention discloses a temporo-mandibular joint biological condyle constructed based on a tissue engineering related technology. The temporo-mandibular joint biological condyle is characterized bycomprising an upper cartilage layer, a middle cellular hydrogel layer and a lower phrenological compound layer which are mutually laminated, wherein the upper cartilage layer comprises a tissue surface making contact with an upper articular disc, a connecting surface making contact with the middle cellular hydrogel layer and a dense tissue layer positioned between the tissue surface and the connecting surface. According to the temporo-mandibular joint biological condyle disclosed by the invention, on the basis of ensuring accurate control over a three-dimensional morphological structure, functional reconstruction of a temporo-mandibular joint is realized; besides, the temporo-mandibular joint biological condyle has the advantages of reducing operative wound, facilitating the use in the operation, reducing osteotomy and bone grinding change, avoiding skull base damage and massive hemorrhage risk and the like so as to overcome the defects of current artificial joint replacement and costal cartilage grafting; transformation from joint reconstruction and replacement to joint reconstruction and regeneration is realized.

Description

technical field [0001] The invention relates to tissue engineering regeneration, temporomandibular joint reconstruction surgery and related medical technology fields, in particular to a temporomandibular joint biological condyle constructed based on tissue engineering related technologies. Background technique [0002] Temporomandibular joint reconstruction is an effective method for the treatment of condylar bone-cartilage complex defects caused by advanced osteoarthropathy, joint ankylosis, joint tumors, idiopathic resorption and other diseases. Currently, the most widely used reconstruction techniques are artificial joint replacement and costal cartilage transplantation. Both have the common defect that the reconstruction of temporomandibular joint function cannot be realized, and postoperative complications such as artificial prosthesis loosening, rejection, and costal cartilage absorption occur after operation. Therefore, how to realize the reconstruction of motor func...

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L27/50A61L27/40A61L27/46A61L27/38A61L27/24A61L27/30
CPCA61L27/24A61L27/306A61L27/3817A61L27/3834A61L27/3891A61L27/3895A61L27/46A61L27/50A61L2430/24C08L67/04
Inventor 何冬梅胡逸晖周广东
Owner SHANGHAI NINTH PEOPLES HOSPITAL SHANGHAI JIAO TONG UNIV SCHOOL OF MEDICINE
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